Magnetic particle imaging a novel SPIO nanoparticle imaging technique ; [contributions of the second International Workshop on Magnetic Particle Imaging (IWMPI 2012) held at the University of Lübeck, Germany on March 15 - 16, 2012

Magnetic Particle Imaging (MPI) is a novel imaging modality. In MPI superparamagnetic iron oxide nanoparticles are used as tracer materials. The volume is the proceeding of the 2nd international workshop on magnetic particle imaging (IWMPI). The workshop aims at covering the status and recent developments of both, the instrumentation and the tracer material, as each of them is equally important in designing a well performing MPI. For instance, the current state of the art in magnetic coil design for MPI is discussed. With a new symmetrical arrangement of coils, a field-free line (FFL) can be produced that promises a significantly higher sensitivity compared with the standard arrangement for a FFP. Furthermore, the workshop aims at presenting results from phantom and pre-clinical studies. Front Matter....Pages 1-14 Front Matter....Pages 1-1 Characterization of Resovist® Nanoparticles for Magnetic Particle Imaging....Pages 3-7 Nonlinear Behavior of Magnetic Fluid in Brownian Relaxation: Numerical Simulation and Derivation of Empirical Model....Pages 9-13 Magnetic Particle Imaging Using Ferromagnetic Magnetization....Pages 15-20 Magnetic Particle Imaging: Exploring Particle Mobility....Pages 21-25 System Calibration Unit for Magnetic Particle Imaging: Focus Field Based System Function....Pages 27-31 Front Matter....Pages 33-33 Characterization of Magnetic Nanoparticles for Magnetic Particle Imaging by Magnetorelaxometry, AC Susceptibility, Magnetic Particle Spectroscopy and Static Magnetization Measurements....Pages 35-40 Perspectives of Magnetic Particle Spectroscopy for Magnetic Nanoparticle Characterization....Pages 41-45 Initial MPS Response of Adsorptively-Coated Fluorescent Iron Oxide Nanoparticles....Pages 47-52 Evaluation of Different Magnetic Particle Systems with Respect to Its MPI Performance....Pages 53-57 Determination of System Functions for Magnetic Particle Imaging....Pages 59-64 Front Matter....Pages 65-65 Microfluidic System as a Tool for Magnetic Separation of Human Cells with Diagnostic Relevance....Pages 67-71 Potential of Improving MPI Performance by Magnetic Separation....Pages 73-78 Front Matter....Pages 79-79 Fractionated Magnetic Multicore Nanoparticles for Magnetic Particle Imaging....Pages 81-85 Precision Synthesis of Iron Oxide Nanoparticles and Their Use as Contrast Agents....Pages 87-91 Synthesis of Single-Core Iron Oxide Nanoparticles as a Tracer for Magnetic Particle Imaging....Pages 93-97 New Perspectives for MPI: A Toolbox for Tracer Research....Pages 99-103 Superparamagnetic Iron Oxide Nanoparticles: Evaluation of Stability of SPIONs in Different Milieu for Magnetic Particle Imaging....Pages 105-109 3D Semi-quantification of Nanoparticle Content in Tissue on Experimental and Commercial μ CT-Scanner....Pages 111-115 Biomaterials for Regenerative Medicine: Cytotoxicity of Superparamagnetic Iron Oxide Nanoparticles in Stem Cells....Pages 117-122 Tracer Development for Magnetic Particle Imaging....Pages 123-127 Front Matter....Pages 79-79 The Potential of Magnetic Particle Imaging in the Competitive Environment of Cardiac Diagnostics....Pages 129-134 Iron Oxide Nanoparticles – Tracer for Magnetic Particle Imaging....Pages 135-139 Front Matter....Pages 141-141 Experimental Evaluation of Correlation-Based Image Reconstruction Method for Magnetic Particle Imaging....Pages 143-148 Relaxation in x-space Magnetic Particle Imaging....Pages 149-153 Linear and Shift Invariance of Magnetic Particle Imaging....Pages 155-160 Efficient Positioning of the Field-Free Point in Magnetic Particle Imaging....Pages 161-165 Visualization of Instruments in interventional Magnetic Particle Imaging (iMPI): A Simulation Study on SPIO Labelings....Pages 167-172 Front Matter....Pages 173-173 Red Blood Cells as Magnetic Carriers for MPI Applications....Pages 175-179 Ex Vivo Magnetic Sentinel Lymph Node Detection in Colorectal Cancer with a SPIO Tracer....Pages 181-185 Distribution of Superparamagnetic Nanoparticles in Lymphatic Tissue for Sentinel Lymph Node Detection in Breast Cancer by Magnetic Particle Imaging....Pages 187-191 Behavior of Superparamagnetic Iron Oxides in Magnetic Targeting Models....Pages 193-197 Diagnostic Imaging in Cancer Therapy with Magnetic Nanoparticles....Pages 199-203 Engineering Contrast Agents for Gastrointestinal Magnetic Particle Imaging: The Biological Perspective....Pages 205-210 Visualization of Instruments for Cardiovascular Intervention Using MPI....Pages 211-215 Efficient Encoding Methods for Small Numbers of Pixels to Achieve High Sensitivity for Screening....Pages 217-221 Front Matter....Pages 223-223 Influence of Magnetic Field Optimization on Image Quality Achieved for Efficient Radon-Based Reconstruction in Field Free Line Imaging in MPI....Pages 225-229 Slicing Frequency Mixed Traveling Wave for 3D Magnetic Particle Imaging....Pages 231-235 Magnetic-Particle-Imaging for Sentinel Lymph Node Biopsy in Breast Cancer....Pages 237-241 Experimental 3D X-Space Magnetic Particle Imaging Using Projection Reconstruction....Pages 243-247 Enlarging the Field of View in Magnetic Particle Imaging – A Comparison....Pages 249-253 Front Matter....Pages 223-223 Continuous Focus Field Variation for Extending the Imaging Range in 3D MPI....Pages 255-259 Third Generation X-Space MPI Mouse and Rat Scanner....Pages 261-265 Projection X-Space MPI Mouse Scanner....Pages 267-271 Front Matter....Pages 273-273 Reconstruction of Magnetization Curve Using Magnetic Spectroscopy....Pages 275-279 Multiferroic behavior of BTO-Nanoparticles....Pages 281-285 Point Spread Function Analysis of Magnetic Particles....Pages 287-292 Front Matter....Pages 293-293 Spatially Resolved Measurement of Magnetic Nanoparticles Using Inhomogeneous Excitation Fields in the Linear Susceptibility Range (