Lung Biology in Health & Disease Volume 188 Therapy for Mucus-Clearance Disorders

this Single-source Reference Provides An Up-to-date Exploration Of Current Medications And Devices Used For The Clearance Of Mucus From The Lungs While Simultaneously Providing The Latest Research And Studies To Clearly Guide Scientists Studying The Pathophysiology Of Airway Inflammation And Mucus Clearance, Clinicians And Therapists Treating Patients With Chronic Lung Disease, And Researchers Developing New Medications And Devices To Enhance Airway Clearance. 1. Overview of airway mucus clearance 2. The biophysical properties of mucus 3. Regulation of airway mucus secretion 4. Outcomes for trials of mucoactive therapy 5. Adherence with the use of clearance techniques 6. Taxonomy of mucoactive medications 7. Mucoactive drug delivery 8. Expectorants 9. Mucolytics and mucus clearance 10. Modulation of mucociliary function by drugs and other agents 11. Mucokinetic agents and surfactant 12. Mucoregulatory medications 13. Hyperosmolar solutions and ion channel modifiers 14. Mucoactive agents and the upper airway 15. Issues on regulatory approval of mucoactive drugs 16. Airway-clearance techniques individually tailored to each patient 17. High-frequency oscillation, PEP, and flutter 18. Pediatric mucus clearance by chest physiotherapy: principles and practice 19. Postoperative mucus clearance 20. Management of airway secretions in patients with severe respiratory muscle dysfunction. Mucus clearance from the respiratory tract is a housekeeping job second to none.