Lung Biology in Health & Disease Volume 183 Acute Exacerbations of Chronic Obstructive Pulmonary Disease

This text aids practitioners who seek to diagnose, treat and manage patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) more effectively. It discusses pulmonary gas exchange, muscle function and breathing, water/electrolyte imbalances and end-stage disease. INTRODUCTION......Page 11 PREFACE......Page 13 CONTRIBUTORS......Page 15 CONTENTS......Page 21 Definitions of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 32 Epidemiology of Exacerbations in Chronic Obstructive Pulmonary Disease......Page 36 Effects of Acute Exacerbations on the Natural History of Chronic Obstructive Pulmonary Disease......Page 44 Economic Burden of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 50 Pathophysiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 60 Immunopathology of Chronic Obstructive Pulmonary Disease and Exacerbations of Bronchitis......Page 78 Biomarkers of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 98 Acute Exacerbation of Chronic Obstructive Pulmonary Disease......Page 118 Causes of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 138 Symptoms and Signs of Acute Exacerbation of Chronic Obstructive Pulmonary Disease......Page 152 Pulmonary Gas Exchange in Exacerbations of Chronic Obstructive Pulmonary Disease......Page 168 Radiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 192 Assessment of Severity of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 234 Cardiopulmonary Interaction in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 260 Skeletal Muscles in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 276 Water–Electrolyte Imbalances in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 296 Metabolism and Nutrition in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 312 End-Stage Disease and Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 336 Impact of Sleep on Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 350 Antibiotics......Page 362 Bronchodilators in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 376 Corticosteroids......Page 388 Oxygen Therapy During Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 410 Acute Exacerbations......Page 424 Noninvasive Ventilation in Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 436 Invasive Mechanical Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease......Page 456 Weaning from the Ventilator......Page 506 Rehabilitation and Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 538 Home Management of Exacerbations of Chronic Obstructive Pulmonary Disease......Page 562 Hospital Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 582 Acute Exacerbation of Chronic Obstructive Pulmonary Disease as Outcome of Therapeutic Interventions......Page 602 Future Research on Acute Exacerbations of Chronic Obstructive Pulmonary Disease......Page 618 Index......Page 630 In the 1990s, the two most commonly used definitions of chronic obstructive pulmonary disease (COPD) were those proposed by the European Respiratory Society (1) and American Thoracic Society (2).