پاتوفیزیولوژی کبد: درمان‌ها و آنتی‌اکسیدان‌ها

__Liver Pathophysiology: Therapies and Antioxidants__ is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. Content: Front Matter,Copyright,Dedication,Hepatic Cirrhosis,List of Contributors,Foreword,AcknowledgmentsEntitled to full textSection I: IntroductionChapter 1 - The Liver: General Aspects and Epidemiology, Pages 3-22, P. Muriel Chapter 2 - Structure and Ultrastructure of the Normal and Diseased Liver, Pages 23-44, V. Tsutsumi, T. Nakamura, T. Ueno, T. Torimura, J. Aguirre-García Chapter 3 - Hepatic Apoptosis and Necrosis: Mechanisms and Clinical Relevance, Pages 47-60, F. Xia, L. Zeng, X.R. Yao, B.J. Zhou Chapter 4 - Autoimmune Hepatitis, Pages 61-85, A.J. Czaja Chapter 5 - Pathogenesis of Idiosyncratic Drug Induced Liver Injury, Pages 87-100, L. Dara, Z.-X. Liu, N. Kaplowitz Chapter 6 - Acetaminophen, Pages 101-112, A. Ramachandran, H. Jaeschke Chapter 7 - Liver Regeneration, Pages 113-123, A. Katoonizadeh Chapter 8 - Nitric Oxide in Liver Ischemia–Reperfusion Injury, Pages 125-127, P. Fu, W. Li Chapter 9 - The Immune System and Viral Hepatitis, Pages 129-139, N.A. Fierro, K. Gonzalez-Aldaco, S. Roman, A. Panduro Chapter 10 - The Pathophysiology of Alcoholic Liver Disease∗, Pages 141-157, S.W. French Chapter 11 - Cytokines in Steatohepatitis, Pages 159-168, L. Hammerich, F. Tacke Chapter 12 - Redox Signaling in NASH, Pages 169-180, A. Takaki, D. Uchida, K. Yamamoto Chapter 13 - Amebic Liver Abscess, Pages 181-186, A. Martínez-Palomo, M. Espinosa-Cantellano, G.R. Tsutsumi, V. Tsutsumi Chapter 14 - Role of Cytokines and Reactive Oxygen Species in the Amebic Liver Abscess Produced by Entamoeba histolytica, Pages 187-197, J. Pacheco-Yépez, M. Martínez-Castillo, A. Cruz-Baquero, J. Serrano-Luna, M. Shibayama Chapter 15 - Epigenetics in Liver Disease: Involvement of Oxidative Stress, Pages 199-211, J. Mann Chapter 16 - Role of Oxidative and Nitrosative Stress in Hepatic Fibrosis, Pages 213-224, T.T. Thuy le, T.T.V. Thuy, H. Hai, N. Kawada Chapter 17 - Oxidative and Nitrosative Stress in Chronic Cholestasis, Pages 225-237, I. Grattagliano, P.J. Oliveira, L. Vergani, P. Portincasa Chapter 18 - Cholestasis, Contraceptives, and Free Radicals, Pages 239-258, E. Fernández-Martínez Chapter 19 - Is Human Cirrhosis a Reversible Disease?, Pages 259-265, D. Kershenobich, D.G. Gutiérrez-Reyes Chapter 20 - Obesity and Hepatocellular Carcinoma, Pages 267-277, W. Xu, J. Yu Chapter 21 - Oxidative Stress as a Mechanism for Hepatocellular Carcinoma, Pages 279-287, M. Tarocchi, A. Galli Chapter 22 - Nuclear Factor-Kappa B Actions During the Development of Hepatocellular Carcinoma, Pages 289-293, S. Maeda, W. Shibata Chapter 23 - The Role of Senescence in Hepatic Diseases, Pages 295-308, R. Pacheco-Rivera, J. Arellanes-Robledo, M.C. García de León, M. Shibayama, J. Serrano-Luna Chapter 24 - Exercise, Liver Steatosis, and Free Radicals, Pages 309-322, I.O. Gonçalves, M.J. Martins, J. Beleza, A. Ascensão, J. Magalhães Chapter 25 - The Metabolic Syndrome, Oxidative Stress, and the Liver, Pages 323-329, P. Almeda-Valdés, N.E. Aguilar-Olivos, M. Uribe, N. Méndez-Sánchez Chapter 26 - Liver Diseases in the Elderly, Pages 331-339, K. Tajiri, Y. Shimizu Chapter 27 - Cytokines in Hepatic Injury, Pages 341-354, H. Fukui Chapter 28 - Nrf2: A Key Regulator of Redox Signaling in Liver Diseases, Pages 355-374, K.M. Kim, S.H. Ki Chapter 29 - Redox Regulation by HGF/c-Met in Liver Disease, Pages 375-387, L.E. Gómez-Quiroz, M.C. Gutiérrez-Ruiz, J.U. Marquardt, V.M. Factor, S.S. Thorgeirsson Chapter 30 - Hepatic Metabolism in Liver Health and Disease, Pages 391-400, X. Liu, H. Wang, X. Liang, M.S. Roberts Chapter 31 - Cytochrome P450 and Oxidative Stress in the Liver, Pages 401-419, A.I. Cederbaum Chapter 32 - Drug Hepatic Clearance in Spinal Cord Injury, Pages 421-424, P. García-López, L. Cruz-Antonio, G. Guízar-Sahagún, G. Castañeda-Hernández Chapter 33 - Complications of Cirrhosis: Introduction, Pages 427-433, P. Muriel, E. Fernández-Martínez, S. Montes Chapter 34 - Portal Hypertension—Molecular Mechanisms, Pages 435-449, J.D. Vorobioff, R.J. Groszmann Chapter 35 - Gastroesophageal Varices, Pages 451-473, M. Fernandez, J.G. Abraldes Chapter 36 - Ascites, Pages 475-484, G. Garcia-Tsao Chapter 37 - Reactive Nitrogen and Oxygen Species in Hepatic Encephalopathy, Pages 485-500, S. Rivera-Mancía, L.A. Tristán-López, S. Montes Chapter 38 - Hepatorenal Syndrome, Pages 501-510, I. Graupera, E. Solà, P. Ginès Chapter 39 - Hepatopulmonary Syndrome and Portopulmonary Hypertension, Pages 511-526, S. Raevens, I. Colle Chapter 40 - Experimental Models of Liver Damage Mediated by Oxidative Stress, Pages 529-546, P. Muriel, E. Ramos-Tovar, G. Montes-Páez, L.D. Buendía-Montaño Chapter 41 - Monitoring of Liver Fibrogenesis and Biochemical Diagnosis of Fibrosis, Pages 547-561, O.A. Gressner, A.M. Gressner Chapter 42 - In Vitro Models of HCC, Pages 563-579, J. Arellanes-Robledo, C. Hernández, J. Camacho, J.I. Pérez-Carreón Chapter 43 - The Liver, Oxidative Stress, and Antioxidants, Pages 583-604, S. Casas-Grajales, P. Muriel Chapter 44 - Herbal Drugs on the Liver, Pages 605-620, C. Girish, S.C. Pradhan Chapter 45 - Silymarin for Liver Disease, Pages 621-631, L. Abenavoli, N. Milic Chapter 46 - Naringenin and the Liver, Pages 633-651, E. Hernández-Aquino, P. Muriel Chapter 47 - Antioxidant, Antiinflammatory, and Antifibrotic Properties of Quercetin in the Liver, Pages 653-674, L.F. Vázquez-Flores, S. Casas-Grajales, E. Hernández-Aquino, E.E. Vargas-Pozada, P. Muriel Chapter 48 - Coffee and the Liver, Pages 675-685, J. Arauz, E. Ramos-Tovar, P. Muriel Chapter 49 - Hepatoprotective Properties of Curcumin, Pages 687-704, K. Reyes-Gordillo, R. Shah, M.R. Lakshman, R.E. Flores-Beltrán, P. Muriel Chapter 50 - Retinoids in Liver Function, Pages 705-713, G. Shiota Chapter 51 - Stevia as a Putative Hepatoprotector, Pages 715-727, E. Ramos-Tovar, P. Muriel Chapter 52 - Are N-Acetylcysteine and Resveratrol Effective Treatments for Liver Disease?, Pages 729-742, E. Chávez, M. Galicia-Moreno, P. Muriel Chapter 53 - Does Nutrition Matter in Liver Disease?, Pages 743-759, E. Ramos-Tovar, P. Muriel Chapter 54 - One-Carbon Metabolism in Liver Health and Disease, Pages 761-765, J.M. Mato, M.L. Martínez-Chantar, M. Noureddin, S.C. Lu Chapter 55 - Ursodeoxycholic Acid for the Treatment of Liver Diseases, Pages 767-779, J.-Y. Wang, S.-D. Wu Chapter 56 - Current Treatment of Chronic Hepatitis C, Pages 781-789, P. Ferenci Chapter 57 - An Adenosine Derivative Compound as a Hepatoprotective Agent, Pages 791-798, V. Chagoya de Sánchez, M. del Pilar Cabrales-Romero, G. Velasco-Loyden Chapter 58 - Nitric Oxide and the Liver, Pages 799-816, P.A. Loughran, L. Xu, T.R. Billiar Chapter 59 - Repopulation of Cirrhotic Liver by Hepatic Stem/Progenitor Cells: A Promising Strategy Alternative to Liver Transplantation, Pages 817-836, A.A. Khan, S.K. Vishwakarma, A. Bardia, M.A. Habeeb, M. Dhayal Chapter 60 - Gene Therapy for Liver Disease, Pages 837-851, R.N. Aravalli Chapter 61 - Role of Oxidative Stress in Liver Transplantation, Pages 853-868, A. Casillas-Ramírez, M.B. Jiménez-Castro, A.Y. Rocha-Sánchez, H.Y. Martínez-Padrón, J. Gracia-Sancho, C. Peralta Index, Pages 869-881

Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants.

Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies.

• Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury.
• Provides in vivo and in vitro models to study human liver pathology.
• Explains the beneficial effects of antioxidants on liver diseases.
• Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.