LH-RH and its analogues fertility and antifertility aspects ; [proceedings of an internat. workshop held in 1983

Sinceits founding by Jacques Waardenburg in 1971, Religion and Reason has been a leading forum for contributions on theories, theoretical issues and agendas related to the phenomenon and the study of religion. Topics include (among others) category formation, comparison, ethnophilosophy, hermeneutics, methodology, myth, phenomenology, philosophy of science, scientific atheism, structuralism, and theories of religion. From time to time the series publishes volumes that map the state of the art and the history of the discipline. Opening remarks Opening remarks Contents Physiological basis for clinical use of LH-RH and its analogues Hypothalamic control of gonadotropin secretion and ovarian function Induction of ovulation in amenorrhea infertile women with pulsatile administration of gonadotropin releasing hormone Effects of different substituents in the A-ring of estradiol on its potency in sensitizing pituicytes to gonadotropin releasing hormone Present status of LH-RH analog chemistry Pharmacology of GnRH analogues Binding sites for LH-RH in the human — does LH-RH exert extrapituitary actions in man? Influence of LH-RH and des-Gly 10 [D-Ala 6 ]-LH-RH ethylamide on the biosynthesis of hCG in placental tissue culture The pharmacologic profile of [(ImBzl)-D-His 6 ,Pro 9 -NEt]-LH-RH (ORF 17070), an LH-RH agonist Reversible pharmacologic castration of the female: implications for endometriosis, contraception and ovulation induction Metabolism and pharmacokinetics of LH-RH agonists Studies on controlled release systems for LH-RH analogues Comparative reproductive pharmacology of LH-RH agonist and antagonist: contraceptive, therapeutic and safety aspects Comparative non-human primate studies with LH-RH analogues Long-term suppression of ovulation in the stumptailes macaque by active immunization against LH-RH or by LH-RH agonist administration LH-RH agonists in the male: basic and clinical studies A new approach to male contraception using combined androgen and GnRH analog treatment LH-RH analog therapy of precocious puberty Treatment of prostatic cancer with LH-RH analogues and control of therapy by cytology and DNA cytophotometry Clinical experience (up to 40 months) with the LH-RH agonist Buserelin in the therapeutic approach to prostatic cancer Antigonadal properties of LH-RH agonists: therapeutical applications in human Contraceptive use of LH-RH agonists LH-RH analogs and luteal function of the rhesus monkey The effects of an LH-RH agonist on the premenstrual syndrome: a preliminary report Discontinous intranasal application of the LH-RH analogon Buserelin in combination with an oral progestin in healthy female volunteers Reversible down-regulation of pituitary-ovarian function induced by repetitive LH-RH agonist administration as a new approach for treatment and study of endometriosis in the human The treatment of endometriosis with LH-RH agonists Concluding remarks List of First-mentioned Contributors