Levine's Pharmacology: Drug Actions and Reactions, Seventh Edition (PHARMACOLOGY- DRUG ACTIONS & REACTIONS (LEVINE))

Completely revised and updated, this is the seventh edition of Levine's classic pharmacology textbook. Known for it's thorough coverage and intelligent organization, the book covers the basic principles of pharmacological interactions on the human body in a way that is useful for both undergraduate and graduate students. Beginning with historical perspectives, nomenclature and definitions, the topics broaden to include sites and mechanisms of drug actions and travel to sites of action, as well as termination and elimination. The book also includes drug response and time-response relationships, response variability, drug toxicity, drug abuse, drug dependence, and more. The heritage of pharmacology The scope of pharmacology How drugs act on the living organism How drugs reach their site of action. I. General principles of passage of drugs across biologic barriers. II. Absorption. III. Distribution How the actions of drugs are terminated. I. Excretion. II. Biotransformation General principles of the quantitative aspects of drug action. I. Dose-response relationships. II. Time-response relationships Factors modifying the effects of drugs in individuals. I. Variability in response attributable to the biologic system. II. Variability in response attributable to the conditions of administration Drug toxicity How drugs alter physiologic function The pharmacologic aspects of drug abuse The development and evaluation of new drugs Glossary Appendixes. 1. Drugs for treating gastrointestinal tract disorders. 2. Drugs for modifying renal function. 3. Drugs for treating infections and cancer. 4. Drugs for treating hypertension. 5. Drugs for reducing pain and consciousness. 6. Drugs for producing sedation and sleep. 6. Drugs for treating mood disorders. 7. Drugs for stimulating the central nervous system Index. The heritage of pharmacology The scope of pharmacology How drugs act on the living organism How drugs reach their site of action I. General principles of passage of drugs across biologic barriers II. Absorption III. Distribution How the actions of drugs are terminated I. Excretion II. Biotransformation General principles of the quantitative aspects of drug action I. Dose-response relationships II. Time-response relationships Factors modifying the effects of drugs in individuals I. Variability in response attributable to the biologic system II. Variability in response attributable to the conditions of administration Drug toxicity How drugs alter physiologic function The pharmacologic aspects of drug abuse The development and evaluation of new drugs Glossary Appendixes Drugs for treating gastrointestinal disorders Drugs for modifying renal functions Drugs for treating infections and cancer Drugs for treating hypertension Drugs for reducing pain and consciousness Drugs for producing sedation and sleep Drugs for treating mood disorders Drugs for stimulating the central nervous system Index. "This is a revised and updated edition of Dr. Levine's classic textbook on basic pharmacologic principles and the general concepts of chemical-biological interactions within the human body. Originally written for students majoring in the sciences and the humanities, it has been widely accepted by pharmacology, medical pharmacy, veterinary and other allied health students. The book is known for its exceptionally thorough coverage, superb presentation and intelligent organization."--Résumé de l'éditeur Pharmacology is the unified study of the properties of chemical agents (drugs) and living organisms and all aspects of their interactions.