Leptospira and Leptospirosis (Current Topics in Microbiology and Immunology Book 387)

This volume covers all aspects of infection by pathogenic __Leptospira__ species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of __Leptospira__. Contact information is also provided for __Leptospira__ reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis. History Of Leptospirosis And Leptospira / Ben Adler -- Systematics Of Leptospiraceae / Paul N. Levett -- Leptospiral Structure, Physiology, And Metabolism / Caroline E. Cameron -- Genomics, Proteomics, And Genetics Of Leptospira / Mathieu Picardeau -- Leptospirosis In Humans / David A. Haake And Paul N. Levett -- Animal Leptospirosis / William A. Ellis -- The Molecular Basis Of Leptospiral Pathogenesis / Gerald L. Murray -- The Leptospiral Outer Membrane / David A. Haake And Wolfram R. Zückert -- Host Response To Leptospira Infection / Richard L. Zuerner -- Vaccines Against Leptospirosis / Ben Adler -- The Role Of Leptospirosis Reference Laboratories / Rudy A. Hartskeerl And Lee D. Smythe -- Index. Ben Adler, Editor. Includes Bibliographical References And Index. This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the worldĺls most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis. ℗l Front Matter....Pages i-viii History of Leptospirosis and Leptospira ....Pages 1-9 Systematics of Leptospiraceae ....Pages 11-20 Leptospiral Structure, Physiology, and Metabolism....Pages 21-41 Genomics, Proteomics, and Genetics of Leptospira ....Pages 43-63 Leptospirosis in Humans....Pages 65-97 Animal Leptospirosis....Pages 99-137 The Molecular Basis of Leptospiral Pathogenesis....Pages 139-185 The Leptospiral Outer Membrane....Pages 187-221 Host Response to Leptospira Infection....Pages 223-250 Vaccines Against Leptospirosis....Pages 251-272 The Role of Leptospirosis Reference Laboratories....Pages 273-288 Back Matter....Pages 289-293