Knowledge Representation for Health Care : HEC 2016 International Joint Workshop, KR4HC/ProHealth 2016, Munich, Germany, September 2, 2016, Revised Selected Papers

This book constitutes the refereed proceedings of two workshops held at the International Conference on Health – Exploring Complexity and Medical Informatics Europe, HEC 2016, held in Munich, Germany, in September 2016: the 8th International Workshop on Knowledge Representation for Health Care, KR4HC 2016, and the 9th International Workshop on Process-oriented Information Systems in Healthcare, ProHealth 2016. The 8 revised full papers were carefully reviewed and selected from 12 submissions. The papers are organized in topical sections on ontologies in health care; clinical quality, evaluation, and simulation; computer guidelines engineering and usage; and comorbidity and clinical process management. Preface 6 Organization 8 Contents 9 Ontologies in Health Care 11 Can Existing Biomedical Ontologies Be More Useful for EHR and CDS? 12 1 Introduction 12 2 Background 13 2.1 EHR Systems 13 2.2 CDS Systems 15 3 Ontologies in the Interface EHR-CDS 16 4 Increasing the Usefulness of Ontologies 20 4.1 Ontology Enrichment 22 4.2 Ontology Quality Evaluation: The OQuaRE Framework 23 5 Discussion and Conclusions 25 References 27 Clinical Quality, Evaluation, and Simulation 30 Formalization and Computation of Diabetes Quality Indicators with Patient Data from a Chinese Hospital 31 1 Introduction 31 2 Materials and Methods 32 2.1 Quality Indicators 32 2.2 Patient Data 32 2.3 CLIF Tool 35 2.4 Evaluation 36 3 Results 37 3.1 Formalization of the Indicators 37 3.2 Computed Results of the Indicators 38 3.3 Analysis and Evaluation of the Results 38 4 Related Work 40 5 Discussion 41 6 Conclusion 42 7 Future Work 42 References 42 Simulation-Based Episodes of Care Data Synthetization for Chronic Disease Patients 44 Abstract 44 1 Introduction 44 2 Methods 46 2.1 The Medical Knowledge Level 47 2.2 The Patient Simulation Level 51 2.3 The Episode of Care Data Synthetization Level 52 3 Synthesizing EoC Data of Patients with Hypertension 53 3.1 Prevalent Information 54 3.2 Decision Tables 54 3.3 Generating Episodes of Care 54 4 Discussion, Conclusions, and Future Work 56 References 57 A Public Health Surveillance Platform Exploiting Free-Text Sources via Natural Language Processing a ... 59 Abstract 59 1 Introduction 59 2 Related Work 61 3 Methods 62 3.1 Data Sources 62 3.2 Platform Modules 62 3.3 Annotation of NLP Results via Linked Data 63 3.4 Micro-services Approach 64 4 Results 65 4.1 Platform Implementation 65 4.2 Proof-of-Concept Application 67 5 Discussion 71 5.1 Contribution 71 5.2 Limitations and Lessons Learned 72 5.3 Future Work 72 References 73 Computer Guideline Engineering and Usage 76 Knowledge-Driven Paper Retrieval to Support Updating of Clinical Guidelines 77 1 Introduction 78 2 Semantic-Distance Method for Guideline Update 79 3 TMR Model Applied for Guideline Update 80 4 Extracting PubMed-Queries from TMR Model 82 4.1 Experiment Method 82 4.2 Implementation and Design Choices 84 4.3 SPARQL Queries 84 5 Experiments 85 5.1 Breast Cancer Guideline 85 5.2 Results and Analysis 88 6 Discussion 91 7 Conclusion 93 References 94 Applying SPARQL-Based Inference and Ontologies for Modelling and Execution of Clinical Practice Guidelines: A Case Study on Hypertension Management 96 1 Introduction 97 2 Background 98 3 Case Study and Requirements 99 3.1 Case Study 99 3.2 Requirements 100 4 Approach and Methodology 101 4.1 Ontology 101 4.2 SPARQL-Based Inference 102 4.3 Rule Definitions 102 5 Results 106 6 Discussion 108 7 Conclusions 110 References 111 Comorbidity and Clinical Process Management 114 Generating Conflict-Free Treatments for Patients with Comorbidity Using Answer Set Programming 115 1 Introduction 115 2 Answer Set Programming 117 3 Finding Preferred Conflict-Free Treatments 117 4 Case Study 120 5 Conclusion 122 References 122 Detecting New Evidences for Evidence-Based Medical Guidelines with Journal Filtering 124 1 Introduction 124 2 Evidence-Based Guidelines and Guideline Updates 126 3 Finding New Evidences with Journal Filtering 128 4 Experiment and Results 130 5 Conclusion 135 References 135 Author Index 137 Front Matter....Pages I-X Front Matter....Pages 1-1 Can Existing Biomedical Ontologies Be More Useful for EHR and CDS?....Pages 3-20 Front Matter....Pages 21-21 Formalization and Computation of Diabetes Quality Indicators with Patient Data from a Chinese Hospital....Pages 23-35 Simulation-Based Episodes of Care Data Synthetization for Chronic Disease Patients....Pages 36-50 A Public Health Surveillance Platform Exploiting Free-Text Sources via Natural Language Processing and Linked Data: Application in Adverse Drug Reaction Signal Detection Using PubMed and Twitter....Pages 51-67 Front Matter....Pages 69-69 Knowledge-Driven Paper Retrieval to Support Updating of Clinical Guidelines....Pages 71-89 Applying SPARQL-Based Inference and Ontologies for Modelling and Execution of Clinical Practice Guidelines: A Case Study on Hypertension Management....Pages 90-107 Front Matter....Pages 109-109 Generating Conflict-Free Treatments for Patients with Comorbidity Using Answer Set Programming....Pages 111-119 Detecting New Evidences for Evidence-Based Medical Guidelines with Journal Filtering....Pages 120-132 Back Matter....Pages 133-133