Kelley's Textbook of Rheumatology: Expert Consult Premium Edition - Enhanced Online Features and Print, 2-Volume Set, 9e

Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book’s sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face. * Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. * Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms. Better manage your patients with in-depth understanding of today's scientific underpinnings of rheumatic diseases using latest advancements in bioengineering, epigenetics and disease-modifying drugs. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued. Content: Front Matter, Pages i-iii Copyright, Page iv Dedication, Pages v-vii Contributors, Pages ix-xxiii Preface, Page xxv 1 - Biology of the Normal Joint, Pages 1-19.e6 2 - Synovium, Pages 20-32 3 - Cartilage and Chondrocytes, Pages 33-60.e10 4 - Biology, Physiology, and Morphology of Bone, Pages 61-66 5 - Muscle: Anatomy, Physiology, and Biochemistry, Pages 67-78 6 - Biomechanics, Pages 79-89 7 - Regenerative Medicine and Tissue Engineering, Pages 90-96 8 - Proteinases and Matrix Degradation, Pages 97-115 9 - Dendritic Cells, Pages 117-133.e6 10 - Mononuclear Phagocytes in Rheumatic Diseases, Pages 134-151 11 - Neutrophils, Pages 152-169 12 - Eosinophils, Pages 170-173 13 - T Lymphocytes, Pages 174-190 14 - B Cells, Pages 191-214 15 - Fibroblasts and Fibroblast-like Synoviocytes, Pages 215-231 16 - Mast Cells, Pages 232-244.e5 17 - Platelets, Pages 245-254 18 - Innate Immunity, Pages 255-267 19 - Adaptive Immunity and Organization of Lymphoid Tissues, Pages 268-280 20 - Autoimmunity, Pages 281-298.e5 21 - Genetics of Rheumatic Diseases, Pages 299-315.e3 22 - Epigenetics, Pages 316-324 23 - Complement System, Pages 325-339 24 - Prostaglandins, Leukotrienes, and Related Compounds, Pages 340-357 25 - Cell Recruitment and Angiogenesis, Pages 358-368.e5 26 - Cytokines, Pages 369-381 27 - Cell Survival and Death in Rheumatic Diseases, Pages 382-399.e4 28 - Experimental Models for Rheumatoid Arthritis, Pages 400-412.e4 29 - Neural Regulation of Pain and Inflammation, Pages 413-429.e6 30 - Principles of Epidemiology in Rheumatic Disease, Pages 431-439 31 - Economic Burden of Rheumatic Diseases, Pages 440-451 32 - Clinical Trial Design and Analysis, Pages 452-461 33 - Assessment of Health Outcomes, Pages 462-475.e3 34 - Biologic Markers, Pages 476-492.e6 35 - Occupational and Recreational Musculoskeletal Disorders, Pages 493-504 36 - Cardiovascular Risk in Rheumatic Disease, Pages 505-514 37 - Cancer Risk in Rheumatic Diseases, Pages 515-527 38 - Introduction to Physical Medicine, Physical Therapy, and Rehabilitation, Pages 528-539 39 - Pregnancy in the Rheumatic Diseases, Pages 540-558.e3 40 - History and Physical Examination of the Musculoskeletal System, Pages 559-576 41 - Acute Monoarthritis, Pages 577-586 42 - Polyarticular Arthritis, Pages 587-598 43 - The Skin and Rheumatic Diseases, Pages 599-616 44 - The Eye and Rheumatic Diseases, Pages 617-623 45 - Neck Pain, Pages 625-638 46 - Shoulder Pain, Pages 639-664.e4 47 - Low Back Pain, Pages 665-682 48 - Hip and Knee Pain, Pages 683-699 49 - Foot and Ankle Pain, Pages 700-707 50 - Hand and Wrist Pain, Pages 708-720.e3 51 - Temporomandibular Joint Pain, Pages 721-732 52 - Fibromyalgia, Pages 733-751.e4 53 - Synovial Fluid Analyses, Synovial Biopsy, and Synovial Pathology, Pages 753-769.e4 54 - Arthrocentesis and Injection of Joints and Soft Tissue, Pages 770-788.e3 55 - Antinuclear Antibodies, Pages 789-803 56 - Autoantibodies in Rheumatoid Arthritis, Pages 804-817.e5 57 - Acute Phase Reactants and the Concept of Inflammation, Pages 818-829.e4 58 - Imaging Modalities in Rheumatic Diseases, Pages 830-869.e6 59 - Prostanoid Biology and Its Therapeutic Targeting, Pages 871-893.e3 60 - Glucocorticoid Therapy, Pages 894-916.e3 61 - Traditional DMARDs: Methotrexate, Leflunomide, Sulfasalazine, Hydroxychloroquine, and Combination Therapies, Pages 917-940.e6 62 - Immunosuppressive Drugs, Pages 941-956.e4 63 - Anticytokine Therapies, Pages 957-977.e4 64 - Cell-Targeted Biologics and Targets: Rituximab, Abatacept, and Other Biologics, Pages 978-1000 65 - Antihyperuricemic Agents, Pages 1001-1013 66 - Analgesic Agents in Rheumatic Disease, Pages 1014-1033.e3 67 - Psychosocial Management of Rheumatic Diseases, Pages 1034-1043 68 - Nutrition and Rheumatic Diseases, Pages 1044-1058.e3 69 - Etiology and Pathogenesis of Rheumatoid Arthritis, Pages 1059-1108.e5 70 - Clinical Features of Rheumatoid Arthritis, Pages 1109-1136.e4 71 - Treatment of Rheumatoid Arthritis, Pages 1137-1160.e4 72 - Early Synovitis and Early Undifferentiated Arthritis, Pages 1161-1168 73 - Sjögren's Syndrome, Pages 1169-1191.e4 74 - Pathogenesis of Ankylosing Spondylitis and Reactive Arthritis, Pages 1193-1201 75 - Ankylosing Spondylitis, Pages 1202-1220.e5 76 - Reactive Arthritis and Undifferentiated Spondyloarthritis, Pages 1221-1231 77 - Psoriatic Arthritis, Pages 1232-1250 78 - Enteropathic Arthritis, Pages 1251-1268 79 - Etiology and Pathogenesis of Systemic Lupus Erythematosus, Pages 1269-1282 80 - Clinical Features of Systemic Lupus Erythematosus, Pages 1283-1303.e3 81 - Treatment of Systemic Lupus Erythematosus, Pages 1304-1330.e6 82 - Antiphospholipid Syndrome, Pages 1331-1341 83 - Etiology and Pathogenesis of Scleroderma, Pages 1343-1365 84 - Clinical Features and Treatment of Scleroderma, Pages 1366-1403.e4 85 - Inflammatory Diseases of Muscle and Other Myopathies, Pages 1404-1430.e5 86 - Overlap Syndromes, Pages 1431-1451 87 - Classification and Epidemiology of Systemic Vasculitis, Pages 1453-1460 88 - Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu's Arteritis, Pages 1461-1480 89 - Antineutrophil Cytoplasm Antibody–Associated Vasculitis, Pages 1481-1497.e4 90 - Polyarteritis Nodosa and Related Disorders, Pages 1498-1507 91 - Immune Complex–Mediated Small Vessel Vasculitis, Pages 1508-1517 92 - Primary Angiitis of the Central Nervous System, Pages 1518-1524 93 - Behçet's Disease, Pages 1525-1532 94 - Etiology and Pathogenesis of Hyperuricemia and Gout, Pages 1533-1553.e5 95 - Clinical Features and Treatment of Gout, Pages 1554-1575.e5 96 - Calcium Crystal Disease: Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate, Pages 1576-1596.e4 97 - Familial Autoinflammatory Syndromes, Pages 1597-1615.e4 98 - Pathogenesis of Osteoarthritis, Pages 1617-1635.e8 99 - Clinical Features of Osteoarthritis, Pages 1636-1645 100 - Treatment of Osteoarthritis, Pages 1646-1659.e4 101 - Metabolic Bone Disease, Pages 1660-1679.e4 102 - Proliferative Bone Diseases, Pages 1680-1691 103 - Osteonecrosis, Pages 1692-1711.e5 104 - Relapsing Polychondritis, Pages 1712-1718 105 - Heritable Diseases of Connective Tissue, Pages 1719-1739.e3 106 - Etiology and Pathogenesis of Juvenile Idiopathic Arthritis, Pages 1741-1751 107 - Treatment of Juvenile Idiopathic Arthritis, Pages 1752-1770.e4 108 - Pediatric Systemic Lupus Erythematosus, Dermatomyositis, Scleroderma, and Vasculitis, Pages 1771-1800.e9 109 - Bacterial Arthritis, Pages 1801-1814 110 - Lyme Disease, Pages 1815-1828.e3 111 - Mycobacterial Infections of Bones and Joints, Pages 1829-1840 112 - Fungal Infections of Bones and Joints, Pages 1841-1850 113 - Rheumatic Manifestations of Human Immunodeficiency Virus Infection, Pages 1851-1864 114 - Viral Arthritis, Pages 1865-1874.e3 115 - Poststreptococcal Arthritis and Rheumatic Fever, Pages 1875-1887 116 - Amyloidosis, Pages 1889-1897 117 - Sarcoidosis, Pages 1898-1906.e1 118 - Hemochromatosis, Pages 1907-1914 119 - Hemophilic Arthropathy, Pages 1915-1923 120 - Rheumatologic Manifestations of Hemoglobinopathies, Pages 1924-1926 121 - Endocrine Diseases and the Musculoskeletal System, Pages 1927-1933 122 - Musculoskeletal Syndromes in Malignancy, Pages 1934-1950.e6 123 - Tumors and Tumor-like Lesions of Joints and Related Structures, Pages 1951-1970 Index, Pages i1-i88 Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book's sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face.Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints. Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. Gain a thorough understanding of the'whys'and'hows'of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms. Apply the latest therapeutic advances through new chapters in bioengineering and tissue engineering, as well as up-to-date coverage of gout and disease-modifying drugs. Learn how the study of biomarkers across populations can help you detect diseases earlier and with greater accuracy with a new chapter on epigenetics. Diagnose, monitor, and manage rheumatic disease more effectively with expanded information on the use of ultrasound and other imaging modalities. Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book's sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face. Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints. Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms