Kelley's Textbook of Rheumatology: 2-Volume Set, Expert Consult: Online and Print 8th Edition

Staying current in a field that's advancing rapidly is difficult. Now more than ever, Kelley's Textbook of Rheumatology, 8th Edition helps you better understand today's scientific underpinnings of rheumatic diseases, so that you can better manage your patients. With its new full-color design, scholarly approach to scientific concepts, and sweeping updates, you'll have a source of knowledge at your disposal to help you face even your toughest challenges. And, as an Expert Consult title, this thoroughly updated 8th edition comes with access to the complete contents online, fully searchable-enabling you to consult it rapidly from any computer with an Internet connection.Provides access to the complete contents online, fully searchable, enabling you to consult it rapidly from any computer with an Internet connection. Features state-of-the-art, evidence-based guidance to help you offer your patients the best possible outcomes.Provides an increased understanding of mechanisms and molecules involved in the pathogenesis of disease. Includes detailed coverage of the very latest breakthroughs and the newest clinical algorithms to help you gain a thorough understanding of the whys as well as the hows of rheumatic disease management.Features new expert authors and new chapters that help you identify key effector mechanisms in autoimmune diseases and inflammation and apply the newest therapeutic modalities. Provides fresh, cutting-edge perspectives from the newest addition to the editorial team, Dr. Iain McInnes. Offers expanded coverage of imaging modalities so you can diagnose, monitor, and manage rheumatic disease more effectively.Incorporates a new full-color design-complete with more than 900 full-color illustrations-for quick access to the answers you need. Designed To Help The Specialist Better Understand Today's Scientific Underpinnings Of Rheumatic Diseases. This Edition Includes Detailed Coverage Of The Latest Breakthroughs And The Newest Clinical Algorithms, New Chapters That Help Identify Key Effector Mechanisms In Autoimmune Diseases And Inflamation And Apply The Newest Therapeutic Modalities, And Offers Expanded Coverage Of Imaging Modalities To Aid In Diagnosing, Monitoring, And Managing Rheumatic Disease More Effectively. V. I: -- Biology Of The Normal Joint -- Synovium -- Cartilage And Chondrocytes -- Biology, Physiology, And Morphology Of Bone -- Muscle: Anatomy, Physiology, And Biochemistry -- Joint Biomechanics: The Role Of Mechanics And Joint Pathology -- Proteinases And Matrix Degradation -- Mononuclear Phagocytes In Rheumatic Diseases -- T Lymphocytes -- B Cells -- Fibroblasts And Fibroblast-like Synoviocytes -- Neutrophils And Eosinophils -- Mast Cells -- Platelets And Rheumatic Diseases -- Autoimmunity -- Innate Immunity -- Adaptive Immunity Including Organization Of Lymphoid Tissues -- Genetics Of Rheumatic Diseases -- Complement System -- Signal Transduction -- Prostaglandins, Leukotrienes, And Related Compounds -- Cell Recruitment And Angiogenesis -- Cell Survival And Death In Rheumatic Diseases -- Animal Models Of Inflammatory Arthritis -- Neurologic Regulation Of Inflammation -- Atherosclerosis In Rheumatoid Arthritis -- Principles Of Epidemiology In Rheumatic Disease --^ Economic Burden Of Rheumatic Diseases -- Clinical Trial Design And Analysis -- Assessment Of Health Outcomes -- Biologic Markers -- Occupational And Recreational Musculoskeletal Disorders -- Integrative Medicine In Rheumatology: An Evidence-based Approach -- History And Physical Examination Of The Musculoskeletal System -- Monarticular Arthritis -- Polyarticular Arthritis -- Fibromyalgia -- Neck Pain -- Shoulder Pain -- Low Back Pain -- Hip And Knee Pain -- Foot And Ankle Pain -- Hand And Wrist Pain -- Temporomandibular Joint Pain -- The Eye And Rheumatic Diseases -- The Skin And Rheumatic Diseases -- Synovial Fluid Analysis, Synovial Biopsy, And Synovial Pathology -- Arthrocentesis And Injection Of Joints And Soft Tissue -- Antinuclear Antibodies -- Rheumatoid Factors And Other Autoantibodies In Rheumatoid Arthritis -- Acute-phase Reactants And The Concept Of Inflammation -- Imaging Modalities In Rheumatic Disease -- Nonsteroidal Anti-inflammatory Drugs -- Glucocorticoid Therapy --^ Methotrexate, Leflunomide, Sulfasalazine, Hydroxychloroquine, And Combination Therapies -- Immunoregulatory Drugs. Anticytokine Therapies -- Cell-targeted Biologics And Emerging Targets: Rituximab, Abatacept, And Other Biologics -- Chronic Musculoskeletal Pain -- Arthritis Self-management -- Psychosocial Management Of Rheumatic Diseases -- Nutrition And Rheumatic Diseases -- Introduction To Physical Medicine And Rehabilitation -- V. Ii -- Etiology And Pathogenesis Of Rheumatoid Arthritis -- Clinical Features Of Rheumatoid Arthritis -- Treatment Of Rheumatoid Arthritis -- Felty's Syndrome -- Sjören's Syndrome -- Ankylosing Spondylitis -- Undifferentiated Spondyloarthritis And Reactive Arthritis -- Psoriatic Arthritis -- Enteropathic Arthritis -- Pathogenesis Of Systemic Lupus Erythematosus -- Clinical Features And Treatment Of Systemic Lupus Erythematosus -- Antiphospholipid Syndrome -- Systemic Sclerosis And The Scleroderma-spectrum Disorders -- Inflammatory Diseases Of Muscle And Other Myopathies -- Overlap Syndromes -- The Classification And Epidemiology Of Systemic Vasculitis --^ Giant Cell Arteritis, Polymyalgia Rheumatica, And Takayasu's Arteritis -- Antineutrophil Cytoplasmic Antibody-associated Vasculitis -- Polyarteritis And Related Disorders -- Isolated Angiitis Of The Central Nervous System -- Immune Complex-mediated Small Vessel Vasculitis -- Behçet's Disease -- Gout And Hyperuricemia -- Diseases Associated With Articular Deposition Of Calcium Pyrophosphate Dihydrate And Basic Calcium Phosphate Crystals -- Pathogenesis Of Osteoarthritis -- Clinical Features Of Osteoarthritis -- Management Of Osteoarthritis -- Metabolic Bone Disease -- Proliferative Bone Diseases -- Osteonecrosis -- Relapsing Polychondritis -- Heritable Diseases Of Connective Tissue -- Juvenile Idiopathic Arthritis -- Systemic Lupus Erythematosus, Juvenile Dermatomyositis, Scleroderma, And Vasculitis -- Bacterial Arthritis -- Lyme Disease -- Mycobacterial Infections Of Bones And Joints -- Fungal Infections Of The Bones And Joints --^ Rheumatic Manifestations Of Human Immunodeficiency Virus Infection -- Viral Arthritis -- Poststreptoccocal Arthritis And Rheumatic Fever -- Amyloidosis -- Sarcoidosis -- Hemochromatosis -- Hemophilic Arthropathy -- Rheumatic Manifestations Of Hemoglobinopathies -- Arthritis Accompanying Endocrine And Metabolic Disorders -- Musculoskeletal Syndromes In Malignancy -- Familial Autoinflammatory Syndromes -- Tumors And Tumor-like Lesions Of Joints And Related Structures. [edited By] Gary S. Firestein ... [et Al.]. An Expert Consult Title--cover. Rev. Ed. Of: Kelley's Textbook Of Rheumatology / Edward D. Harris, Jr. ... [et Al.]. C2005. Includes Bibliographical References And Index.