نشریه انجمن شیمی‌دانان آزمایشگاه‌های مخفی ۱۹۹۰-۲۰۱۷

Journal Index 90-95 JCLIC 1990 October In This Issue ... PRESIDENT’S MESSAGE ABOUT THIS ISSUE BUSINESS YEAR CHANGES IN THIS ISSUE OF THE JOURNAL CONTRIBUTIONS TO THE JOURNAL THAT’S A WRAP COMMITTEE MEMBERS SOUGHT TRAINING AND RESOURCES: SEMINAR: LEGISLATIVE COMMITTEE: MEMBERSHIP: PUBLICATIONS: FOR YOUR INFORMATION LABORATORIES SEIZED IN NORTH CAROLINA UNUSUAL PRECURSOR SHIPPED TO OREGON UNUSUAL REACTION CONTAINER ENCOUNTERED VARIOUS ROUTES ENCOUNTERED IN THE CENTRAL VALLEY OF CALIFORNIA IR, Vapor IR, and MS Spectra NMR Spectra CATALYTIC REDUCTIONS OF EPHEDRINE UP IN SOUTHERN CALIFORNIA EPHEDRINE TABLETS STILL BEING ENCOUNTERED AS PRECURSOR SOURCE HASHISH LABORATORY SEIZED IN WASHINGTON STATE REFERENCES “Application of HPLC Mobile Phase Optimization Methods to the Detection of Impurities in Bulk Drug Steroids” “Column and Stationary Phase Selection in GC” “Ice: A New Dosage Form of An Old Drug” “Formation of Amphetamine From Its Nitro Analogue by Anaerobic Intestinal Bacteria” “Stereoselective Syntheses of Ephedrine and Related 2-Aminoalcohols of High Optical Purity from Protected Cyanohydrins” “Liquid Chromatographic Properties and Aqueous Solution Stability of N-Hydroxy-3,4-methylenedioxyamphetamine” JCLIC 1991 April In This Issue PLANS FOR FIRST ANNUAL SEMINAR ON CLANDESTINE LABORATORIES SEPTEMBER 4-7,1991 WEDNESDAY, SEPTEMBER 4: THURSDAY, SEPTEMBER 5: FRIDAY AND SATURDAY, SEPTEMBER 6 AND 7: CONFERENCE COSTS FUNDING IDEAS FOR MORE INFORMATION EXECUTIVE BOARD MEETING MINUTES SUPREME COURT TO CONSIDER GOVERNMENT’S TEMPORARY SCHEDULING AUTHORITY RECOMMENDED NEW FEDERAL SENTENCING GUIDELINES PUBLISHED “ICE” DEFINED CLANDESTINE LABORATORIES AND PRECURSOR CHEMICALS BENZALDEHYDE - NITROETHANE LABS STILL BEING SEEN IN THE WEST REPORTS OF SEIZURES OF CLANDESTINE LABORATORIES LABORATORY SEIZURES IN CENTRAL TEXAS DMT LABORATORY SEIZED IN RHODE ISLAND LARGE PCP LAB AND DISTRIBUTION RING BROKEN IN RHODE ISLAND VENTING DEVICE SUBSTANTIATES DRUG LAB IN KERN COUNTY, CALIFORNIA UNDERGROUND LAB DISCOVERED IN SOUTHERN CALIFORNIA METHAMPHETAMINE RECOVERY FROM WASTE SOLUTIONS FOUND IN CONTRA COSTA COUNTY, CALIFORNIA PRECURSOR STOLEN FROM PORTLAND STATE UNIVERSITY BENZALDEHYDE – NITROETHANE LAB SEIZED IN PORTLAND LEAD ACETATE LABORATORY SEIZED IN NORTH CENTRAL OREGON LITERATURE REFERENCES “Methods for the Determination of Methamphetamine from Regioisomeric Phenethylamines,” “Synthesis of Dextroamphetamine Sulfate and Methamphetamine Hydrochloride from D-Phenylalanine,” “Synthesis of Chiral alpha-Alkyl Phenethylamines via Organometallic Addition to Chiral 2-Aryl-1,3-oxazolidines,” “Analysis of Impurities in Methamphetamine,” “Amphetamine-like Effects in Humans of the Khat Alkaloid Cathinone,” “Pharmacological Properties of the Stimulant Khat,” “Determination of Heroin and Some Common Adulterants by Capillary Gas Chromatography,” “An Outbreak of Designer Drug Related Deaths in Pennsylvania,” “Methamphetamine Synthesis via Hydriodic Acid / Red Phosphorus Reduction of Ephedrine,” “An Investigation of the Extraction of Methamphetamine from Chicken Feed, and Other Myths,” “Asymmetric Animation of 4-Methoxyphenylacetone and Its Related Compounds With Microorganisms,” “Psychotropic Drugs in Australia: Consumption Patterns,” “A Novel Extraction Procedure for Psilocybin and Psilocin Determination in Mushroom Samples,” “Detection of Pseudoecgonine and Differentiation from Ecgonine in Illicit Cocaine,” “Chemical and Physical Properties of (Z)- and (E)- Monoethoxy-1-(2-nitro-1-propenyl)benzenes: Important Precursors to the Monoethoxyamphetamines,” JCLIC 1991 January WELCOME!! LETTERS TO THE EDITOR DEA WANTS TO CLOSE LOOPHOLE FEDERAL DRUG CHEMICAL LAW HAILED AS A SUCCESS IMPROVISED EXPLOSIVE DEVICE PROFILES INFORMATION ON LAB SEIZURES “ICE” METHAMPHETAMINE LAB SEIZED IN SOUTHERN CALIFORNIA BENZALDEHYDE / NITROETHANE ROUTE TO PHENYL-2- PROPANONE LABORATORY SEIZED IN OREGON. MISLABELED CHEMICAL CONTAINER LIKELY CAUSE OF N,N-DLMETHYLAMPHETAMINE IN TEXAS FIRST METH LAB IN SOUTHEAST ALASKA SEIZED METHAMPHETAMINE AND AMPHETAMINE LABORATORIES SEIZED IN AUSTRALIA TRAVEL TRAILER FOUND TO CONTAIN CLANDESTINE LABORATORY RE-USE OF HCL CYLINDERS POSE SAFETY HAZARD FOR INVESTIGATORS DIVERSION OF CHEMICALS DISCOVERED IN COLORADO STATE HEALTH LABORATORY N,N-DLMETHYLAMPHETAMINE LABORATORY SEIZED IN WASHINGTON STATE LARGE MULTI-DRUG CLANDESTINE LABORATORY SEIZED IN SEATTLE, WA REMOTE LAB IN PENNSYLVANIA SEIZED STATE POLICE TRAINING MATERIALS SEIZED AT CLANDESTINE LABORATORY SITE PCP BASE ENCOUNTERED IN FRESNO AREA ARIZONA DPS LAB REPORTS THREE LAB SEIZURES MAKESHIFT LAB SEIZED IN EL DORADO COUNTY, CA REFERENCES “Normal Phase TLC Separation of Enantiomers Using Chiral Ion Interaction Agents” “Reactive Airway Dysfunction Syndrome in Three Police Officers Following a Roadside Chemical Spill” “Synthesis of lndoles via Ring Closure of 2- Alkylnitroaniline Derivatives” “Synthesis of 11-Nor-delta8 Tetrahydrocannabinol-9-carboxylic Acid Methyl Ester” “Reductive Amination of Aldehydes and Ketones with Weakly Basic Anilines Using Sodium Triacetoxyborohydride” “Reductive Amination of Aldehydes and Ketones by Using Sodium Triacetoxyborohydride” “The Carcinogenic Potential of Cocaine” “A Novel Approach to (+)-Yohimbine” “Methods for the Analysis and Characterization of Forensic Samples Containing Amphetamines and Related Amines” “Mechanism of the Neurotoxicity of MPTP • An Update” “Flexible N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Analogues: Synthesis and Monoamine Oxidase Catalyzed Bioactivation” JCLIC 1991 July In This Issue LETTERS TO THE EDITOR POSSIBLE USE OF DIMETHYL UREA DISCUSSED TYPOGRAPHICAL ERROR IN MDA RECIPE DETAILS OF TECHNICAL MEETING IN SAN DIEGO SCHEDULE OF ACTIVITIES September 4: September 5: September 6 & 7: CALL FOR PAPERS AND POSTERS REGISTRATION FOR MORE INFORMATION ASSOCIATION’S FUTURE TOPIC OF FIRST ANNUAL MEETING WHAT DIRECTION SHOULD THE ASSOCIATION TAKE? SITE FOR NEXT MEETING CLANDESTINE LABORATORY ROUNDTABLE AT THE AMERICAN ACADEMY MEETING STRONGER CONTROLS URGED ON CHEMICALS CHEMICAL COMPANY PRESIDENT GETS 23-MONTH PRISON SENTENCE STATUTE DEFINING CONTROLLED SUBSTANCE ANALOG NOT UNCONSTITUTIONALLY VAGUE DRUG LABORATORY SEIZURES METHAMPHETAMINE LAB SEIZED IN WESTERN NORTH CAROLINA METHAMPHETAMINE - METHADONE LABORATORY SEIZED IN WASHINGTON STATE LITERATURE REFERENCES “Contamination of Clandestinely Prepared Drugs With Synthetic By-Products” “Gas Chromatographic and Mass Spectrometric Analysis of Samples from a Clandestine Laboratory Involved in the Synthesis of Ecstacy from Sassafras Oil” “Illegal Drug Laboratories: A Growing Health and Toxic Waste Problem” THE USE OF LATENT PRINTS IN THE INVESTIGATION OF CLANDESTINE DRUG LABS T.R. EKIS, MAX COURTNEY, AND J.M. MABERRY INTRODUCTION CASE HISTORY BACKGROUND METHODOLOGY DATA ASSEMBLY RESULTS Analysis by where evidence was processed: Effect of Comparison with Major Case Prints: Assembled or Disassembled Labs: Time Element: DISCUSSION Policy Implications: REFERENCES Table 1. Comparison of fingerprint data from latent prints taken from clandestine lab equipment and other exhibits. A SPREADSHEET PROGRAM FOR THE DETERMINATION OF VOLUMES OF ONE AND TWO PHASE LIQUIDS IN ROUND BOTTOM REACTION FLASKS ROGER A. ELY INTRODUCTION DISCUSSION SOFTWARE AND HARDWARE CONSIDERATIONS INSTALLATION OBTAINING THE SPREADSHEETS REFERENCES Figure 1. Figure 2. An example of the printed output from the spreadsheet LIQ_VOL1.XLS. Figure 3. An example of the output from the spreadsheet SHORT2.XLS. Table 1. Estimated total volumes (ml) for round bottom reaction flasks METHAMPHETAMINE VIA THE PRESSURE COOKER DONN CHRISTIAN AND ROGER SCHNEIDER ABSTRACT INTRODUCTION CASE HISTORIES EXPERIMENTAL Reaction Ratios Instrument Parameters Chromatographic Conditions Mass Selective Detector Conditions Quantitation RESULTS DISCUSSION CONCLUSION REFERENCES Table 1. Reaction Mixture Components JCLIC 1991 October IN THIS ISSUE CLIC TO HOLD ROUND TABLE AT AMERICAN ACADEMY MEETING IN NEW ORLEANS ASSOCIATION BUSINESS Minutes Of Executive Board Meeting September 3, 1991 San Diego, CA Minutes Of General Meeting September 5, 1991 San Diego, CA Committee Reports: Old Business - None New Business Minutes Of General Meeting - Continued September 7, 1991 San Diego, CA Meeting Location Projects - Tom Abercrombie Miscellaneous ‘TWAS THE NIGHT TO MAKE CRYSTAL NEW MEMBERS ADDED TO ASSOCIATION Associate Members: Regular Members: UNDERGROUND BOOKS IN PRINT RECENT FEDERAL DECISIONS: LAB PROSECUTIONS AND A FEW OTHERS QUESTIONS REGARDING SCHEDULING OF METHAMPHETAMINE AND OTHER DRUGS QUESTIONS REGARDING CALCULATION OF SENTENCING GUIDELINES AND STATUTORY PENALTIES OTHER QUESTIONS REGARDING METHAMPHETAMINE LABS AND THEIR PROSECUTION TEMPORARY SCHEDULING PROVISION AUTHORITY UNCERTAIN METHAMPHETAMINE IN OVER-THE-COUNTER PREPARATIONS DOES NOT EFFECT SCHEDULING VICK’S INHALER DEFENSE AMOUNT OF DRUG THAT COULD HAVE BEEN PRODUCED PROPERLY USED IN DETERMINING OFFENSE LEVEL AN IMPROVED PREPARATION OF PHENYLACETONE ABSTRACTS FROM FIRST TECHNICAL MEETING FIRST CLIC MEETING A GREAT SUCCESS ABSTRACTS FROM WORKSHOPS “TECHNOLOGY OF IMPROVISED EXPLOSIVE DEVICES” “THE FEDERAL PROSECUTION OF CLANDESTINE DRUG LABORATORIES” ABSTRACTS OF KEYNOTE SPEAKERS “INVESTIGATION OF CLANDESTINE DRUG LABS - PAST AND PRESENT” “DON’T METH WITH ME!” “ASPECTS OF ILLICIT DRUG MANUFACTURE IN THE UNITED KINGDOM” ABSTRACTS FROM POSTER SESSION “Large Scale Methamphetamine Laboratories Seized in Los Angeles County, California” “Phencyclidine Clandestine Laboratory” “Synthetic Routes of Hydriodic Acid” ABSTRACTS OF TECHNICAL PAPERS “Variations of Leuckart-Type Amphetamine Syntheses” “Further Data Treatment of Clandestine Lab Fingerprint Cases” “Fast Automatic Identification of Drugs of Abuse by GC/ FTIR” “An Empirical Yield Study of An Ephedrine Reduction Method” “Results of Reactions When a Substitute for Hydriodic Acid is Used in the Hydriodic Acid / Red Phosphorus / Ephedrine Synthetic Route” “Production Estimates of Clandestine Laboratory Seizures” “Phenyl-2-propanone Synthesis Using the Tube Furnace” “Methamphetamine Via The Pressure Cooker” “The Occurrence of Anti-HIV Compounds in Clandestine Laboratory Investigations” “Confidentiality of Documents” “The Ephedrine - Hydriodic Acid Reaction: Mechanism and Variations” “Drug Analysis in Canada” “Clandestine Laboratory Safety - Past, Present and Future” “Differentiation of Phenyl-2-propanone Synthesized From Phenylacetic Acid With Acetic Anhydride or Lead (II) Acetate” “Identification of Oxazolidines as a New Class of Impurities Found in Methamphetamine” “Forensic Drug Analysis by GC/FTIR” “Illicit Drug Characterization Using FTIR Spectroscopy” “Seizure of a Large Scale Amphetamine Laboratory” “Safety in an Underground Work Place” “Large-Scale Methamphetamine Clandestine Laboratory - Wisconsin’s Kountry Kitchen” “Clandestine Laboratory Manual of Instruction and Procedure. An Overview” CLANDESTINE LABORATORY SEIZURES AMPHETAMINE LABORATORY SEIZED IN KALGOORLIE, WESTERN AUSTRALIA MAJOR MDMA LABORATORY FOUND IN FRANCE CLANDESTINE “TENT” LAB FOUND AT LAKE WOMAN DIES OF OPIUM “TEA” OVERDOSE WHILE WE’RE ON THE SUBJECT ... EXPLOSIVES LAB SEIZED IN STOCKTON, CA METHAMPHETAMINE LAB EXPLODES IN SOUTHERN CALIFORNIA CUDL OPERATION DISCOVERED IN NORTHERN CALIFORNIA UNUSUAL REDUCING AGENT PURCHASED IN PORTLAND, OR AREA LITERATURE REFERENCES “ICE: Poor Man’s Cocaine” “Synthesis and Pharmacological Examination of 1-(3- Methoxy-4-methylphenyl)-2-aminopropane and 5-Methoxy- 6-methyl-2-aminodan: Similarities to 3,4-(Methylenedioxy)- methamphetamine (MDMA)” “Synthesis, Stereochemistry, and Biological Activity of the 1-(1-Phenyl-2-methylcyclohexyl)piperidines and the 1-(1-Phenyl-4-methylcyclohexyl)piperidines. Absolute Configuration of the Potent trans-(-)-1-(1-Phenyl-2- methylcyclohexyl)piperidine.” “Design, Synthesis, and Pharmacological Evaluation of Ultrashort- to Long-Acting Opioid Analgetics.” “Synthesis of Hydriodic Acid.” N-ACETYLNORCOCAINE: A NEW COCAINE IMPURITY FROM CLANDESTINE PROCESSING. I. ABSTRACT INTRODUCTION EXPERIMENTAL Synthesis of N-acetylnorcocaine: Trans-esterification: Hydrochloride conversion via methanol/acetyl chloride: RESULTS AND DISCUSSION REFERENCES ESTABLISHING THE ILLEGITIMATE USE OF TRICHLOROMONOFLUOROMETHANE IN CLANDESTINE METHAMPHETAMINE LABORATORY INVESTIGATIONS ABSTRACT DISCUSSION Freon-11 as an Extraction Solvent Legitimate Uses of Freon-11 Differentiating Legitimate and illegitimate Usage of Freon Chiller Cooling Systems Industrial Uses Cost of Freon-11 The Future of Freon-11 CONCLUSION REFERENCES PIHKAL - A Chemical Love Story JCLIC 1992 April IN THIS ISSUE MINUTES OF EXECUTIVE BOARD MEETING December 14, 1991 Fresno, CA MINUTES OF EXECUTIVE BOARD MEETING February 18, 1992 New Orleans, LA DEA PLANS TO PLACE METHCATHINONE IN SCHEDULE I POSSESSION OF “SPEED” NOT MANUFACTURING; NO PRESENTLY USEABLE QUANTITY REQUIRED FOR POSSESSION A GUEST “... OF ALL THE NERVE” HUMPTY DUMPTY’S DAY IN COURT DEFENSE EXPERT TESTIFIES: LSD ON BLOTTER PAPER IS NOT A MIXTURE LITERATURE REFERENCES “Passive Inhalation of Cocaine” “Designer Drugs” “Optically Pure Chiral Sulfoxides Using Ephedrine as a Chiral Auxiliary” “Hmong Folk Remedies: Limited Acetylation of Opium by Aspirin and Acetaminophen” “Enantiomeric Separation of α-Phenylethylamine and its Substituted Isomers by Gas Chromatography” “N-Modified Analogues of Cocaine: Synthesis and Inhibition of Binding to the Cocaine Receptor” “For Your Information: Preparation of Lithium Aluminum Hydride Solutions” “Identification of N-Formylnorcocaine and N-Benzoylnormethylcocaine in Illicit Cocaine” “Evaluation of Gas Chromatography-Fourier Transform Infrared Spectroscopy-Mass Spectroscopy for Analysis of Phenolic Compounds” “Assay of the Optical Isomers of Methamphetamine and Amphetamine in Rat Urine Using High-Performance Liquid Chromatography with Chiral Cellulose-base Columns” “Simultaneous HPLC Analysis of Optical Isomers of Methamphetamine and Its Metabolites, and Stereo-selective Metabolism of Racemic Methamphetamine in Rat Urine” “Late Intermediates in the Biosynthesis of Cocaine: 4-(1- Methyl-2-pyrrolidinyl)-3-oxobutanoate and Methyl Ecgonine” “Nuclear Magnetic Resonance (NMR) Spectroscopic Investigation of Interaction Energies of Ephedrine Stereoisomers in Noncrystalline Solids and Its Correlation With Thermodynamic Data” LABORATORY SEIZURES LARGE SCALE NITROSTYRENE LAB SEIZED IN NORTHERN CALIFORNIA ASPIRIN – OPIUM MIXTURES RESULT IN HEROIN MAJOR EPHEDRINE TABLET EXTRACTION LAB FOUND Photo 1. Recyclene R-2A REDUCTION OF PHENYLPROPANOLAMINE TO AMPHETAMINE IN CENTRAL CALIFORNIA FRAUDULENT LSD SAMPLE RECOVERED: SAFETY WARNING BENZENE HAZARDS AT CLANDESTINE LAB SITES UNUSUAL P2P LAB SEIZED IN PHOENIX AZ DRUG LAB COOK FOUND DEAD IN WASHINGTON STATE POLY-DRUG LABORATORY SEIZED IN AUSTIN, TEXAS METHAMPHETAMINE, MDMA LAB DISCOVERED NEAR COLORADO – WYOMING BORDER METHCATHINONE SAMPLES SEIZED IN WISCONSIN EXTRACTION OF METHAMPHETAMINE FROM PH PAPERS USEFUL PHENYL-2-PROPANONE LABS ON A COMEBACK IN NORTHERN CALIFORNIA; NEW LAWS BEING FORMULATED CAUTION URGED IN SAMPLING RED PHOSPHORUS, ARSON ANALYSIS ON COCAINE SAMPLES JCLIC 1992 January IN THIS ISSUE 2ND ANNUAL TECHNICAL TRAINING SEMINAR SET IN FORT WORTH INTERESTED AND QUALIFIED CANDIDATES SOUGHT CLIC ROUNDTABLE SESSION AT AMERICAN ACADEMY MEETING THE CIRCLE, INC., TO DEVELOP MODEL CLANDESTINE DRUG LABORATORY ENFORCEMENT PROGRAM COURT ORDERS SHERIFF TO QUIT MAKING CRACK THE DRUG LAB WAS A PHANTOM BUT THE SENTENCE WAS REAL: DEA COOKS SPEED MANUFACTURER’S GOOSE NEW FEDERAL SENTENCING GUIDELINES IN EFFECT ACTUAL VERSUS PURE “ICE” Impact on Analyses. PRECURSOR CHEMICALS IN DRUG LABS Precursors: Essential Chemicals: Impact on Analyses. LABORATORY SEIZURES BURNED-OUT LAB FOUND IN ARIZONA EPHEDRINE TABLET LAB SEIZED IN PORTLAND, OR DEA LABORATORY REPORTS TRENDS IN SOUTHEAST UNITED STATES CA DOJ LAB - CHICO BUSY DURING NOVEMBER AND DECEMBER BOOBY TRAPPED LAB DISCOVERED IN COLORADO HIKERS WATCH CHEMICAL DUMP METHAQUALONE LAB SEIZED NEAR BAKERSFIELD PLATING SOLUTION CONTAINING HYDRIODIC ACID SEIZED LITERATURE REFERENCES “Methamphetamine - Stimulant of the 1990s?” “Illicit Methamphetamine: Analysis, Synthesis, and Availability” “The Rise, Decline, and Fall of LSD” “Legal Liabilities Faced By Owners of Property Contaminated By Clandestine Methamphetamine Laboratories: The Oregon Approach” CHINESE EPHEDRINE INTRODUCTION THE EPHEDRA PLANT AND THE USES OF EPHEDRINE The five predominant species of the Ephedra plant CONCLUSION SEPARATION AND IDENTIFICATION OF DRUG ENANTIOMERS VIA N-TFA-(S)-PROLYL CHLORIDE DERIVATIZATION ABSTRACT EXPERIMENTAL INTRODUCTION Reagents Instrumental Conditions Procedure RESULTS CONCLUSION Figures: Chiral center of amphetamine molecule Structural configuration of the diastereomers of ephedrine and pseudoephedrine Table of MS peaks for phenethylamines Second chiral center of the ephedrines TIC, MS of l-ephedrine TPC TIC, MS of d-pseudoephedrine TPC TIC, MS of d-methamphetamine TPC TIC, MS of d-amphetamine TPC REFERENCES A DISCUSSION OF “COCAINE BASE” AND “COCAINE” – THE CASE LAW CONCERNING THE SUFFICIENCY OF THE DEFINITION OF COCAINE BASE, THE CORRECT DEFINITION OF COCAINE BASE, AND WHICH “MIXTURES” SHOULD BE TREATED AS COCAINE BASE FOR PURPOSES OF SENTENCING INTRODUCTION COCAINE BASE FROM COLOMBIA AND COCAINE BASE MADE FROM COCAINE HYDROCHLORIDE THE INCORRECT DEFINITION OF COCAINE BASE THE CORRECT DEFINITION OF COCAINE BASE REFERENCES JCLIC 1992 July IN THIS ISSUE PLANS FOR 2ND ANNUAL TECHNICAL TRAINING SEMINAR ANNOUNCED LSD TRENDS AND SYNTHESES WORKSHOP HIGHLIGHTED Schedule Wednesday, Sept. 9 Thursday, Sept. 10 Friday, Sept. 11 Saturday, Sept. 12 ABOUT THE MEETING SITE REGISTRATION FOR MORE INFORMATION RECENT U.S. FEDERAL COURT DECISIONS CORNMEAL MIXED WITH COCAINE IMPROPERLY INCLUDED IN WEIGHT OF SUBSTANCE FOR SENTENCING PURPOSES DRUGS NOT CHARGED IN INDICTMENT PROPERLY USED TO DETERMINE SENTENCE LAX: A NEW DRUG REFERENCES LABORATORY SEIZURES GRIGNARD SYNTHESIS OF METHYLAMPHETAMINE IN WESTERN AUSTRALIA MULTIPLE METHODS ENCOUNTERED IN VICTORIA “ECSTASY” LAB TAKEN DOWN DESPITE BOOBY TRAPS CA DOJ LABORATORY AT CHICO MEETS “WILLIE PETE” ROAD FLARES USED AS SOURCE OF RED PHOSPHORUS RECIPE FOR MAKING HYDRIODIC ACID SEIZED BURIED LAB SITES IN THE HIGH DESERT OF SOUTH CENTRAL CALIFORNIA BURIED LAB SITE FOUND IN SAN BERNARDINO COUNTY, CALIFORNIA COLORADO LAB SEIZURES NOTED; BETTER YIELD OF EPHEDRONE REPORTED 3-METHYLFENTANYL LAB SEIZED NEAR MOSCOW CHICO BUSY WITH LAB SEIZURES ALTERNATIVE METHOD FOR ACCESSING DIETHYL ETHER CANS SEIZURE OF BURIED LABORATORIES ON THE RISE; CONFINED SPACE CREATES EXTREME SAFETY HAZARD CONFINED SPACE SAFETY AND THE CLANDESTINE LABORATORY FELONY CONVICTION IN BURBANK CONFINED SPACE ACCIDENT CONFINED SPACES: GENERAL INDUSTRY SAFETY ORDERS TITLE 8 CALIFORNIA CODE OF REGULATIONS ARTICLE 108 Article 108 Confined Spaces 5156. Scope and Definitions. 5157. Operating Procedures and Employee Training. 5158. Pre-entry. 5159. Confined Space Operations COMPARISON OF WESTERN US MANUFACTURING AND PRECURSOR LAWS REGULATED PRECURSORS PENALTIES FOR MANUFACTURING JCLIC 1992 October IN THIS ISSUE SAFETY ALERT: NEW “COLD METHOD” LABS ON INCREASE Diagram of reaction setup DEA PLACES AMINOREX IN TEMPORARY SCHEDULE I OF CONTROLLED SUBSTANCES ACT DEA IMPOSES EXPORT CONTROLS ON HYDROCHLORIC AND SULFURIC ACIDS BOOK ON CLANDESTINE LABORATORY CHEMICALS AVAILABLE DEA SEEKS CHANGES IN CHEMICAL DIVERSION LAWS WARNING ON ‘CRAZY’ NEW DRUG CONFINED SPACE RULES HOPED FOR IN OCTOBER CASE STUDY OF CONFINED–SPACE DEATH ILLUSTRATES NEED FOR WRITTEN PROCEDURE STATE RULES INVESTIGATION RECOMMENDATIONS SECOND ANNUAL TECHNICAL TRAINING SEMINAR HIGHLIGHTS LSD SEMINAR BRING YOUR OWN SLIDES SESSION BINDERS AVAILABLE ABSTRACTS OF PRESENTATIONS MADE AT THE 2ND ANNUAL TECHNICAL TRAINING SEMINAR WORKSHOPS “Trends In LSD Trafficking” “LSD Synthesis Workshop” “Developments In Federal Law Concerning Clandestine Drug Laboratories” “Developments In Texas Law Concerning Clandestine Drug Laboratories” “Analysis And Sampling Of Clandestine Laboratory Exhibits” “Microchemical Techniques In Clandestine Laboratory Analysis” “Courtroom Presentation Of Clandestine Drug Laboratory Cases” POSTER PRESENTATIONS “Phosphorus And Iodine As A Source Of Hydriodic Acid” “Representative Sampling Of “Street” Drug Exhibits” “Serial Dry Extraction Of Illicit Methamphetamine Powders For The Identification Of Adulterants And Diluents By Infrared Spectroscopy” “Clandestine Laboratory Producing And Using Propylhexedrine From Benzedrex Inhalers” “Alternatives To Phenyl-2-Propanone As A Precursor In The Synthesis Of Amphetamine Or Methamphetamine” “Texas-Branded Speed” TECHNICAL PRESENTATIONS “Having A Blast With Ether” “CLIC Member Safety Survey” “Who Needs Regulated Chemicals? Phenylacetone Synthesis via Friedel-Crafts Alkylation” “Estimation Of Drug Product Yields From Clandestine Laboratory Synthesis Routes” “Synthesis Of Phenethylamines Through The Leuckart Reaction” “Some Noteworthy Clandestine Laboratories Seized In The Midwestern United States: A Slide Presentation” “From The Kitchen Of Uncle Fester” “In Search Of Reason: Evaluating Clandestine Labs for Court” LAB SEIZURES LARGE PRODUCTION LAB FOUND AT BIG SUR,CA ILLEGAL CAT LAB FOUND IN UPPER MICHIGAN PENINSULA COCAINE EXTRACTION LABORATORY SEIZED IN TORONTO CLANDESTINE LAB CAUSES SMALL FOREST FIRE CHICO AREA COOKS RELYING ON HOUSEHOLD ITEMS HISPANIC GANGS ASSOCIATED WITH CENTRAL CA LABS METHCATHINONE LABORATORY SEIZED IN SEATTLE, WA STOVE–TOP LAB IGNITES IN LAS VEGAS, NV MDMA, PHENYLACETONE LAB SEIZED IN ORANGE CO.,CA WHO NEEDS REGULATED CHEMICALS? PHENYLACETONE SYNTHESIS THROUGH A FRIEDEL-CRAFTS ALKYLATION THE FRIEDEL–CRAFTS REACTION HISTORICAL BACKGROUND FOR SYNTHESIS OF PHENYLACETONE PHENYLACETONE SYNTHESIS VIA FRIEDEL–CRAFTS PROCEDURE INSTRUMENTAL ANALYSIS: RESULTS DISCUSSION REFERENCES COURTROOM PRESENTATION OF CLANDESTINE DRUG LABORATORY CASES ABSTRACT INTRODUCTION CASE PREPARATION PRETRIAL CONFERENCE TESTIMONY CROSS EXAMINATION INDEPENDENT EXPERT VISUAL AIDS Photographs Slides Flip Charts And Overheads Evidence Exhibits COMBINATION OF VISUAL AIDS CONCLUSION REFERENCES A CLANDESTINE LABORATORY EXTRACTING PROPYLHEXEDRINE FROM BENZEDREX INHALERS BACKGROUND MATERIALS AND METHODS ANALYSIS ON SAMPLES TFAP - Enantiomeric Determination MBTFA - Structural Determination CONCLUSIONS REFERENCES Figure 1. Structure of propylhexadrine, active ingredient in Benzedrex inhalers Figure 2. Figure 3. IN SEARCH OF REASON: EVALUATING CLANDESTINE LABS FOR COURT INTRODUCTION ADULTERANTS, ETC. SAMPLING PROBLEMS DEPTH OF ANALYSIS LAB CAPABILITIES, ETC. CONCLUSION REFERENCES JCLIC 1993 April In This Issue ... OSHA Publishes Confined Space Rule Chemical Firm Sues Over DEA Pressure: It Says Agents Harass Customers Solvent Used In Analysis May React With Amines CLIC Training Committee Looking For Slides DEA Places alpha-Ethyltryptamine Into Emergency Schedule I Laboratory Seizures MEXICAN NATIONAL METHAMPHETAMINE LABS CREEP INTO NORTHERN CALIFORNIA LARGE PHENYL-2-PROPANONE LAB DISCOVERED IN SEATTLE NEW MINI–THINS HIT CALIFORNIA MARKET AGENTS, SUSPECT INJURED IN HAYWARD, CA LAB UTAH EXPERIENCES A WIDE VARIETY OF CLANDESTINE SYNTHESES Ephedrine Pill Distributors Targeted In DEA Sting Making Methamphetamine From “Chicken Scratch” MDA Operation Seized On U.S. Military Base Safety Matchbooks Used As Source Of Red Phosphorus In Methamphetamine Laboratory Figure 1. Chemical components of a matchbook RESEARCH AND DEVELOPMENT LAB SEIZED IN COOS BAY, OR PSEUDOEPHEDRINE EXTRACTION LAB DISCOVERED MOPE DOPE Physical Characteristics Of Active Cook Sites Numbers Of Active Lab Sites Encountered And Geographical Changes The Mother Of All Mope Dope Labs PCP SOLUTIONS SEEN IN KANSAS CITY, MISSOURI RED MERCURIC OXIDE PURCHASED INSTEAD OF RED PHOSPHORUS SLURPY MACHINE USED IN CLANDESTINE LAB NEWS FROM NORTHWEST OREGON 1-Phenyl-2-Nitropropene Route Popular Catalytic Reduction Of Ephedrine Unexpected Submission Of MDA Bunk Samples Encountered Iodine Crystals: The Clandestine Lab Investigator's Friend And Enemy Figure 1: Iodine Fuming Gun commonly used in fingerprint development. Figure 2. Photograph of fingerprint recovered from the top of an ephedrine tablet bottle JCLIC 1993 January IN THIS ISSUE CLIC STARTING SEIZED CLANDESTINE LABORATORY NOTES AND RECIPE COLLECTION ASSOCIATION TRAINING COMMITTEE SEEKS MATERIAL CONFINED SPACE INCIDENT KILLS THREE CLANDESTINE LABORATORY SEIZURES CLANDESTINE LAB EXPLODES IN TUCSON, AZ NEW CONTAINERS FOR FREON 11, HYDRIODIC ACID ENCOUNTERED HUGE MDMA LABORATORY SEIZED IN NORTHERN CALIFORNIA WESTERN CANADA BUSY WITH LAB SEIZURES EXPLANATION OF “OX BLOOD” METHAMPHETAMINE CALIFORNIA ENACTS EPHEDRINE TABLET LAW; INCREASE OF HYDRIODIC ACID SALES NOTED ANTI-HIV DRUG LABORATORY FOUND IN FRESNO PRACTICAL ADVICE ON GAS DETECTION FOR CONFINED SPACE ENTRANTS’ SAFETY INHALATION INJURIES, INFORMATION ON HISPANIC GANG METHAMPHETAMINE LAB ACTIVITIES ABSENCE OF CONDENSERS RESULTS IN INHALATION INJURIES HISPANIC GANG CLANDESTINE LABORATORY STRATEGY MEETING AYAHUASCA A VALIDATION STUDY OF THE “COLD METHOD” ABSTRACT METHOD PROCEDURE NUMBER 1 PROCEDURE NUMBER 2 DISCUSSION REFERENCE Figure 1: Reaction vessels Figure 2: TIC of reaction mixture EPHEDRONE SYNTHESES IN RUSSIA SYNTHESIS OF PHENYLACETIC ACID VIA MANDELIC ACID INTRODUCTION EXPERIMENTAL RESULTS AND DISCUSSION CONCLUSION REFERENCE Fig. 1. Mandelic acide reduction to phenylacetic acid Fig. 2. TIC and MS of synthesized phenylacetic acid Table 1. Comparison of literature and seized recipe values Fig. 3. IR spectrum of synthesized phenylacetic acid Fig. 4. TIC and MS of mandelic acid in methanol Fig. 5. TIC and MS of mandelic acid in ethyl ether Fig. 6. IR spectrum of d,l-mandelic acid Fig. 7. Direct insertion probe MS spectrum of mandelic acid SERIAL DRY EXTRACTION OF ILLICIT METHAMPHETAMINE POWDERS FOR THE IDENTIFICATION OF ADULTERANTS AND DILUENTS BY INFRARED SPECTROSCOPY DISCUSSION PROCEDURE SAMPLE PREPARATION First Extraction, Acetone Second Extraction, Chloroform Third Extraction, Methanol Insolubles CONCLUSION REFERENCES Extraction flow chart JCLIC 1993 July In This Issue Cocaine-Tainted Cash Faulted As Evidence DEA Nabs 2 For Making Ultralethal Drug Fentanyl DEA Can't Search At Chemical Company Insurance for Drug Lab Proposed Amendments to The Federal Sentencing Guidelines AMENDMENT 11 AMENDMENT 12 AMENDMENT 13 AMENDMENT 14 AMENDMENT 15 Lab Seizures NEW PHENETHYLAMINE DERIVATIVE ENCOUNTERED FENTANYL LABORATORY SEIZED IN WICHITA, KANSAS COLORADO LAB SEIZURES METH LABS GONE BAD STATE OF NEVADA CONTROLS HYDRIODIC ACID Analytical Profile of Gamma-Hydroxybutyric Acid (GHB) Structure of GHB and GABA Conversion of GHB to GBL References IR spectrum GHB acid MS spectrum GHB Expert Examination of MDA INTRODUCTION THE OBJECTS OF EXAMINATION EXAMINATION DISCUSSION REFERENCES Figure 1. Reaction conversion of isosafrole to MDMA Figure 2. IR spectrum of MDA Figure 3. IR spectrum of MD-P2P Figure 4. IR spectrum of isosafrole JCLIC 1993 October In This Issue ... Appeals of Federal Methamphetamine Sentencing on the Rise Table 1. Drug equivalencies of methamphetamine Developing A Strategy For A Multiagency Response To Clandestine Drug Laboratories Chemical Control Bills Introduced to U.S. Congress Lab Seizures DEA Raids Suspected Drug Lab; Paroled Chemist Among 4 Arrested Ruthenium Oxide Being Purchased As Catalyst Use Of Iodine Crystals Increases In Contra Costa County, CA Aluminum Amalgam Lab Found In Englewood, CO Abstracts of Papers Presented at 3rd Annual Technical Training Seminar Technical papers "Mope Dope and AIDS Curess: Central California Drug Lab Scenes, 1992-1993" "Clandestine Aminorex, A Designer Drug Parent Finds the East Coast" "Disposal Technologies" "Fatalities Resulting From Clandestine Drug Manufacturing Laboratories" "Methamphetamine Synthesis Via Reductive Alkylation Hydrogenolysis of Phenyl-2-Propanone with N-Benzylmethylamine" "Examination of Duct Tape in Clandetine Labs" Poster Session "An Unsuccessful Clandestine Synthesis of Amphetamine "The Use of Chemical Ionizatoin-MS in Analyzing Novel Amphetamine Reaction Mixtures" "Examination of MDA" "Clandestine Drug Lab Chemistry Illustrated" Permit Required Confined Spaces. The New Federal OSHA Regulations The New Federal OSHA Regulations Permit Required Confined Spaces. Federal Register §1910.146 Legal Update on Drug Sentencing / Clan Lab Cases Examination of a Commercial Metal Pickling Agent For the Synthesis of Methcathinone Background Information Experimental Results Isolation and Identification of Phenyl-2-Propanone in Vacuum Pump Oil Introduction Procedure Materials Step one Step two Step three Step four Step five Results and Discussion Conclusion Acknowledgement References Table 1 Figure 1. Extraction flow chart Figure 2. TIC and MS of extracted P2P JCLIC 1994 April In This Issue Safety Alert Adverse Medical Effects From Exposure To Clandestine Drug Laboratories: A Proposed Health Survey Candidates For Association Offices Sought U.S. Drug Enforcement Administration Places Aminorex Into Schedule I of the CSA Elimination of Ephedrine Threshold Proposed By DEA Clandestine Laboratory Investigator's Association to Meet in Edmonton, Canada Laboratory Seizures HI, EPHEDRINE EXTRACTION LABS SEIZED MEXICAN NATIONAL LAB IN DUNLAP, CA TWIST ON HI/RED P PROCEDURE FOUND IN COLORADO AMPHETAMINE - METHAMPHETAMINE LAB SEIZED IN SACRAMENTO COUNTY EPHEDRINE TABLET SUPPLIER IN ARKANSAS INVESTIGATED Photo 1. "Turbo Tabs" Ephedrine tablets Cruising the Information Superhighway METHCATHINONE HOW TO DECIPHER AN INTERNET MESSAGE DIMETHYLTRYPTAMINE (DMT) AYAHUASCA LSD METHAMPHETAMINE LOOMPANICS BOOK REVIEW EPHEDRA PLANT MATERIAL Awareness of Respiratory Equipment Can Prevent Confined Space Tragedy. WRONG AIR LINE PROGRAM FLAWS LINE OF DEFENSE APPROVED EQUIPMENT EIGHT PARADOXES MINOR CHANGES