Intra- and Intermolecular Interactions, Radiation Effects in DNA Cells, and Repair Mechanisms (Physico-Chemical Properties of Nucleic Acids, Vol. 3)

Physico-chemical Properties of Nucleic Acids, Volume III revolves around three major concepts, which are intra- and intermolecular interactions, radiation effects in DNA cells, and repair mechanisms. This volume also presents the stage of specific biological functions and how repair mechanisms relate to the problem of evolution. Comprised of six chapters, this volume begins with the concept of renaturation of polynucleotides. Interactions in nucleic acids and nucleotides are discussed in several chapters. Other topics covered in this volume include polymer and salt-induced condensation of DNA and strand-breaks in the DNA of mammalian cells. The last chapter explores the stability and evolution of DNA in terms of molecular radiobiology. This chapter also presents and reviews some evolutionary problems, specifically the prebiotic evolution. The elements of stabilization and variability of genetic information are also discussed in the last chapter. As with the other volumes, this volume is a valuable reference for students and researchers in the fields of chemistry, biology, molecular biology, microbiology, and biophysics. Content: Front Matter , Page iii Copyright , Page iv Contributors to Volume 3 , Page v Preface , Page vii , JULES DUCHESNE Foreword , Pages ix-xi , MANFRED EIGEN Contents Volume 1 , Page xv Contents of Volume 2 , Page xv CHAPTER 17 - Renaturation of DNA in the Absence and in the Presence of Cu 2+ Ions , Pages 1-17 , H. RICHARD CHAPTER 18 - Interactions in Nucleic Acids , Pages 19-57 , M. LENG, M. DOURLENT, C. HÉLÈNE CHAPTER 19 - The Polymer and Salt-induced Condensation of DNA , Pages 59-76 , L.S. LERMAN CHAPTER 20 - The Interaction of Nucleotides with Bovine Pancreatic Ribonuclease , Pages 77-138 , F.W. BENZ, G.C.K. ROBERTS CHAPTER 21 - The Measurement of Radiation-induced Strand Breaks in the DNA of Mammalian Cells , Pages 139-159 , M.G. ORMEROD CHAPTER 22 - Stability and Evolution of DNA from the point of view of Molecular Radiobiology , Pages 161-201 , M. RADMAN, J. ROMMELAERE, M. ERRERA Author Index , Pages 203-214 Subject Index , Pages 215-219