International Review of Neurobiology, Supplement 1: Neurobiology of the trace metals zinc and copper

Published since 1959, **International Review of Neurobiology** is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering recent advances in the field of neurobiology. Topics covered include chromosome 22 deletion syndrome and schizophrenia; characterization of proteome of human cerebrospinal fluid; hormonal pathways regulating intermale and interfemale aggression; neuronal gap junctions; effects of genes and stress on the neurobiology of depression; quantitative imaging with teh MicroPET small-animal PET tomograph; understanding myelination through studying its evolution Content: Editorial Board , Page ii Front Matter , Page iii Copyright , Page iv CONTRIBUTORS , Page vii PREFACE , Page ix , CARL C. PFEIFFER ZINC DEFICIENCY SYNDROME IN MAN: A HISTORICAL REVIEW , Pages 1-6 , Ananda S. Prasad CONGENITAL MALFORMATIONS OF THE NERVOUS SYSTEM IN ZINC-DEFICIENT RATS , Pages 7-51 , Lucille S. Hurley, Ruth E. Shrader ACUTE STRESS AND TRACE ELEMENT METABOLISM , Pages 53-82 , William R. Beisel, Robert S. Pekarek TRACE ELEMENTS AND BEHAVIOR , Pages 83-103 , Donald Oberleas, Donald F. Caldwell, Ananda S. Prasad PATHOPHYSIOLOGY OF ZINC , Pages 105-124 , Milos Chvapil, Sharon L. Elias, Janet N. Ryan, Charles F. Zukoski IDIOPATHIC HYPOGEUSIA: A DESCRIPTION OF THE SYNDROME AND A SINGLE-BLIND STUDY WITH ZINC SULFATE , Pages 125-140 , Paul J. Schechter, William T. Friedewald, Diane A. Bronzert, Morton S. Raff, Robert I. Henkin A STUDY OF ZINC DEFICIENCY AND COPPER EXCESS IN THE SCHIZOPHRENIAS , Pages 141-165 , Carl C. Pfeiffer, Venelin Iliev AUTHOR INDEX , Pages 167-177 SUBJECT INDEX , Pages 178-180 Volume 42 presents an in-depth review on Alzheimer's Disease as well as a look at several transcription factors. Key Features * Clinical features of stroke and the current stasis of stroke therapy * Alzheimers Disease--pathology, pathological proteins, etiology, pathogenesis, neurotransmitter alterations, and treatment strategies * An examination of the regulation of AP-1 and related transcription factors and their role in brain injury and drug abuse-related behavior * Emerging roles of the transcription factor NF(B * Recent advances about the nature of alterations in ion channel structure or function which may be responsible for epileptogenesis * An integrated model accounting for the multiple mechanisms involved in the posttranslational regulation of glutamate ionotroic receptors * Genetic mutation and the Glycine Receptor International Review of Neurobiology, Supplement 1: Neurobiology of the Trace Metals Zinc and Copper represents a first report in the study of the neurobiology of zinc and copper. Topics covered by this supplementary volume include the effects of zinc deficiency; the link between acute stress and trace element metabolism; the effects of trace elements on behavior; the pathophysiology of zinc; and the role of copper in schizophrenia. This book consists of seven chapters and begins with a historical overview of zinc deficiency syndrome in humans, followed by a discussion on the metabolism of zin ..