Innovative Research in Life Sciences : Pathways to Scientific Impact, Public Health Improvement, and Economic Prosperity

“I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better.” Farah Magrabi, Macquarie University, Australia “The reader will find intriguing not only the title but also the content of the book. I’m also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion.” Elena Andresen, Oregon Health & Science University, USA “This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally.” Gerald Pepe, Eastern Virginia Medical School, USA “This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts.” Zoltán Néda, Babe_-Bolyai University, Romania “I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature.” David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories. "I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better." Farah Magrabi, Macquarie University, Australia "The reader will find intriguing not only the title but also the content of the book. I'm also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion." Elena Andresen, Oregon Health & Science University, USA "This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally." Gerald Pepe, Eastern Virginia Medical School, USA "This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts." Zoltán Néda, Babeş-Bolyai University, Romania "I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature." David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: Highlights the research phase from design to discovery that precedes innovation disclosure Offers a step by step explanation of how to improve innovation Offers solutions for improving research and innovation productivity in the life sciences Contains a variety of statistical databases and a vast number of stories about individual discoveries Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading to biomedical innovation and identifies the best practices of innovative scientists and laboratories. "I thoroughly enjoyed reading this book as it has taken me on a journey through time, across the globe and through multiple disciplines. Indeed, we need to be thinking about these concepts and applying them every day to do our jobs better." Farah Magrabi, Macquarie University, Australia "The reader will find intriguing not only the title but also the content of the book. I'm also pleased that public health, and even more specifically epidemiology has an important place in this ambitious discussion." Elena Andresen, Oregon Health & Science University, USA "This book is very well written and addresses an important topic. It presents many reasons why basic scientists/researchers should establish collaborations and access information outside traditional means and not limit thinking but rather expand such and perhaps develop more innovative and translational research ventures that will advance science and not move it laterally." Gerald Pepe, Eastern Virginia Medical School, USA "This book gathers logically and presents interestingly (with many examples) the qualities and attitudes a researcher must possess in order to become successful. On the long run, the deep and carefully reexamined research will be the one that lasts." ZoltAn NEda, Babes-Bolyai University, Romania "I really liked the five pillars delineating the components of humanism in research. This book has made a major contribution to the research ethics literature." David Fleming, University of Missouri, USA A comprehensive review of the research phase of life sciences from design to discovery with suggestions to improve innovation This vital resource explores the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the production of effective science. Innovative Research in Life Sciences draws on lessons from 400 award-winning scientists and research from leading universities. The book explores the innovative process in life sciences and puts the focus on how great ideas are born and become landmark scientific discoveries. The text provides a unique resource for developing professional competencies and applied skills of life sciences researchers. The book examines what happens before the scientific paper is submitted for publication or the innovation becomes legally protected. This phase is the most neglected but most exciting in the process of scientific creativity and innovation. The author identifies twelve competencies of innovative biomedical researchers that described and analyzed. This important resource: -Highlights the research phase from design to discovery that precedes innovation disclosure -Offers a step by step explanation of how to improve innovation -Offers solutions for improving research and innovation productivity in the life sciences -Contains a variety of statistical databases and a vast number of stories about individual discoveries -Includes a process of published studies and national statistics of biomedical research and reviews the performance of research labs and academic institutions Written for academics and researchers in biomedicine, pharmaceutical science, life sciences, drug discovery, pharmacology, Innovative Research in Life Sciences offers a guide to the creative processes leading t Content: Intro Title Page Copyright Page Contents Preface Part One Outcomes of Research Chapter 1 Pathways of the Research Innovator Diverse Outcomes of Science Best of Both Worlds: Scientific and Innovative Opportunities That Are Not Just Timely But Also Timeless Balancing Research and Innovation Essential Concepts of Research Innovation Research Innovation Pathways to Effects Learning from Award-winning Scientists and Serial Innovators Road to Meaningful Research Disclosure References Chapter 2 First Dimension: Scientific Impact Intellectual Impact and Scientific Pluralism. You Cannot Make a Good Landing Out of a Bad ApproachIntellectual Products of Scientific Endeavors Reality Means Reproducibility One May Not Know in the Beginning How the End Will Look Like References Chapter 3 Second Dimension: Public Health Value Improving Health in Mission Statements of Science The Road from Basic Research to Better Health Breaking Down Silos: Basic Science and Public Health Putting Science to Work and Change Lives High-impact Research Driven by Public Health Needs References Chapter 4 Third Dimension: Economic Development. Economic Impact of Life Sciences ResearchBlockbuster Impact of University Research Good Science Must Come First in Commercialization Without Good Science, There Is No Positive Technology Transfer Impact of Life Sciences on the National Economy Diverse Messages About Economic Impact at Different Levels References Part Two Headwinds of Research Innovation Chapter 5 Slowdown and Erosion Signs of Slowdown in Research Innovation Obstacles to Research Innovation Increasing Costs of Regulatory Compliance The Gamble of Science and "Short-termism." Sputnik Moment: The Need to Accelerate ResearchReferences Chapter 6 Non-reproducible Research The Boulder of Non-reproducible Research Implications of Non-reproducible Results Sources of Non-repeatable Research Results The Undisclosed Becomes Non-repeatable Rare but Troubling: Pathological Science and Fraudulent Research The Way Out: Modeling, Transparency, and Continuous Quality Improvement References Chapter 7 Red Tape and Litigation Bureaucratization of Research Regulatory Burden on Creativity Protection of Intellectual Property. Conflicts over Credit and Case Law of Inventor RecognitionAccountability for Reproducibility References Part Three Boosters of Research Productivity Chapter 8 Humanism for Innovation Research Targeting by Values of Humanism Identifying Measures for Performance Improvement Creativity Needs Diversity of People, Cultures, and Ideas Rock Solid Values When the Controversies Mount Counteracting Flawed Economic and Social Incentives Focus and Motivation for Sacrificial Effort Numbers Need Stories and Stories Need Numbers References Chapter 9 Desire to Understand First. "This book addresses the creative processes leading to biomedical innovation, identifies the obstacles and best practices of innovative laboratories, and supports the generation of impactful science. The author's discussion is based on relevant peer-reviewed original scientific publications, national statistics, historical archives, law and regulation, court cases and case studies of major discoveries and disappointments. By illuminating the outcomes of research, mapping major obstacles and hazards of applied research, advancing quality assurance and improvement, and charting the course leading to practical impact; the book provides a unique resource for developing professional competencies and applied skills of life sciences researchers"--Provided by publisher