Innovations In Neonatal-perinatal Medicine: Innovative Technologies And Therapies That Have Fundamentally Changed The Way We Deliver Care For The Fetus And The Neonate Innovative Technologies and Therapies that have Fundamentally Changed the Way We Delive

Innovations in technology and new therapies have changed the face of medicine in the last few decades. These include advances in fetal diagnosis (preimplantation genetics, chorionic villous sampling and amniocentesis), drugs that have been developed to treat unique conditions in neonates such as respiratory distress syndrome (surfactant) and pulmonary hypertension (inhaled nitric oxide), as well as technological advances and interventions resulting in diagnostic (ultrasounds and MRI) and therapeutic interventions (intrauterine transfusion to ECMO). Research in fertility treatments has resulted in test tube babies and cloned animals, and that has also fostered technological advances in diagnostic and therapeutic interventions. The primary purpose of Innovations in __Neonatal-Perinatal__ Medicine is to highlight these innovations in technology and therapy that have not only changed the way doctors deliver care to fetus and neonate but also reduced neonatal mortality thereby saving millions of lives in the process. These issues are addressed by the authors who are experts in their respective fields. The book will be valuable not only to healthcare providers but also to educators and policy makers Ch. 1. Medical innovations in the 20th century and their impact on neonatal-perinatal medicine : A global perspective. 1.1. Introduction. 1.2. Innovations that influenced population health. 1.3. Growth and influence of internet technology. 1.4. Health related technologies. 1.5. Technology assessment and public policy -- ch. 2. Assisted reproductive technologies. 2.1. Initial evaluation for IVF. 2.2. Patient selection for IVF. 2.3. Testing prior to assisted reproduction. 2.4. Preparation for IVF. 2.5. Fetal safety of drugs in pregnancy. 2.6. IVF protocols. 2.7. Risks of IVF. 2.8. Success rates -- ch. 3. Advances in fetal diagnostics for genomic alterations. 3.1. Origin of genomic imbalances. 3.2. Prenatal screening. 3.3. Prenatal diagnostic testing. 3.4. Prenatal genomic microarray. 3.5. Conclusion -- ch. 4. Fetal imaging in detection of congenita heart disease. 4.1. The significance of congenital heart disease. 4.2. The importance of prenatal diagnosis of CHD. 4.3. Examination of fetal heart. 4.4. Imaging modalities. 4.5. Counseling. 4.6. The impact of fetal echocardiography - Changing the prognosis. 4.7. The impact of fetal echocardiography - Delivery. 4.8. The impact of fetal echocardiography - What can we do for affected fetus/neonates? 4.9. Overall effects of fetal echocardiography on CHD - Can we do better? -- ch. 5. Imaging the newborn brain. 5.1. Ultrasound. 5.2. Magnetic resonance imaging -- ch. 6. Monitoring and intervention therapies in neonatal intensive care units. 6.1. Introduction. 6.2. Monitoring and managing oxygen support. 6.3. Management of hemolytic disease in the fetus and the newborn. 6.4. Phototherapy and management of neonatal jaundice. 6.5. Conclusion -- ch. 7. Regulation of neonatal environment 2010. 7.1. Basic physics of heat transfer. 7.2. Physiology of response to heat loss. 7.3. Human incubation. 7.4. Convection warmed incubators. 7.5. The open radiant warmer bed. 7.6. Hybrid incubator-radiant warmer design. 7.7. Other warming strategies. 7.8. Other clinical scenarios. 7.9. Therapeutic hypothermia for term and near-term neonates - Cerebral protection. 7.10. Summary -- ch. 8. Advances in neonatal nutritional care. 8.1. Historical aspects. 8.2. Protein strategies. 8.3. Future implications of feeding strategies -- ch. 9. Advances in ventilatory care of the neonate. 9.1. Historical perspective. 9.2. Basics of mechanical ventilation. 9.3. Tidal versus non-tidal ventilation via the endotracheal tube. 9.4. Noninvasive ventilation -- ch. 10. Respiratory distress syndrome : Impact of surfactant therapy and antenatal steroid. 10.1. Introduction. 10.2. Surfactant. 10.3. Antenatal steroid. 10.4. Economic impact -- ch. 11. Antibiotics and other miracle drugs. 11.1. Neonatal infections. 11.2. Neural tube defects and folate supplementation. 11.3. Rh hemolytic disease and anti-D globulin. 11.4. Patent Ductus Arteriosus (PDA) and indomethacin. 11.5. Persistent pulmonary hypertension and inhaled nitric oxide. 11.6. Summary -- ch. 12. Impact of surgical innovations. 12.1. Retinopathy of Prematurity (ROP). 12.2. Hypoplastic Left Heart Syndromes (HLHS). 12.3. Transposition of the Great Arteries (TGA). 12.4. Minimal access surgery. 12.5. Fetal surgery "Innovations in technology and new therapies have changed the face of medicine in the last few decades. These include advances in fetal diagnosis (preimplantation genetics, chorionic villous sampling and amniocentesis), drugs that have been developed to treat unique conditions in neonates such as respiratory distress syndrome (surfactant) and pulmonary hypertension (inhaled nitric oxide), as well as technological advances and interventions resulting in diagnostic (ultrasounds and MRI) and therapeutic interventions (intrauterine transfusion to ECMO). Research in fertility treatments has resulted in test tube babies and cloned animals, and that has also fostered technological advances in diagnostic and therapeutic interventions. The primary purpose of Innovations in Neonatal-Perinatal Medicine is to highlight these innovations in technology and therapy that have not only changed the way doctors deliver care to fetus and neonate but also reduced neonatal mortality thereby saving millions of lives in the process. These issues are addressed by the authors who are experts in their respective fields. The book will be valuable not only to healthcare providers but also to educators and policy makers ."--Publisher's website