Innate Immunity to Pulmonary Infection: Novartis Foundation Symposium 279

Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases of the lung. Innate Immunity to Pulmonary Infection: * Provides a comprehensive overview of pulmonary infectious diseases, including basic pathology, current and potential therapies, and detailed consideration of the innate biological resistance mechanisms in the lung * Thoroughly examines the major topic of innate immunity in immunology, which is now seen as key to the pathogenesis of and vaccination strategies for infectious diseases * Describes the genetic and environmental factors which determine the outcome of infection, such as latency of Tuberculosis, blood stream invasion from local infection, and local target tissue damage * Covers the roles of cells such as neutrophils, macrophages and dendritic cells and of molecular components such as Toll-like receptors * Discusses the clinical applications of the new knowledge regarding innate immunity and how this can be used in both treatment and prevention (vaccination) strategies * Includes contributions from an international and interdisciplinary group of experts **__Innate Immunity to Pulmonary Infection__** is an essential resource for researchers in both industry and academia. It is of interest for all those interested in the disciplines of immunology, virology, biology, biotechnology and genetics. Content: Lung Diseases In South Africa: An Overview -- Tb Epidemiology And Human Genetics -- Bacterial Infections Of The Lung In Normal And Immunodeficient Patients -- Pathogenesis Of Avian Flu H5n1 And Sars -- Immunity And Tolerance To Apspergillus Fumigatus -- Pentraxins In Innate Immunity And Inflammation -- How Superoxide Production By Neutrophil Leukocytes Kills Microbes -- Linking Innate To Adaptive Immunity Through Dendritic Cells -- Macrophage Receptors And Innate Immunity: Insights From Dectin-1 -- Toll-like Receptors And Control Of Mycobacterial Infection In Mice -- Population Of Lungs By Mast Cells -- Innate Immunity And Mucus Structure And Function -- Collectins And Host Defence -- Infections And Asthma Pathogenesis: A Critical Role For Dendritic Cells? -- Innate And Adaptive Immunity In Lung Cancer -- Summing Up. [editors: Derek J. Chadwick And Jamie Goode]. Symposium On Innate Immunity To Pulmonary Infection, Held At The Wolfson Pavillion, University Of Cape Town Medical School, South Africa, 28-30 November 2005.--contents. Includes Bibliographical References And Index. Also Available In An Electronic Version. Mode Of Access: World Wide Web.