Inflammatory bowel disease and familial adenomatous polyposis : clinical management and patients' quality of life

Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. The genetic basis of FAP is well known, but there is still debate about IBD, which seems more likely to be a multifactorial disease, where the illness is due to interactions between environmental and genetic factors. In the near future, the aim will be to prevent these disorders and their sequelae through early detection and early intervention (for example genetic therapy). Unfortunately, we are still dealing with young patients with a lifelong disease course, leading to early morbidity (and in some cases mortality) and extended needs for medical treatment, with a consequent decrease in quality of life. IBD and FAP represent a challenge for a multidisciplinary medical approach where different personnel play major roles in different stages of the patient’s treatment. It is in this light that basic scientists, geneticists, pathologists, radiologists, gastroenterologists, surgeons, psychologists and WOC/ET nurses have to work together in order to improve the outlook of these patients and their families. This Book Gathers Current Methods Of Treatment Of Inflammatory Bowel Disease (ibd) And Familial Adenomatous Polyposis (fap) And Also Presents The Management Of Their Complications. Authors Intend To Give A Comprehensive Overview Of The Newer Therapies To Bring The Readers Up To Date. Mri In Inflammatory Small-bowel Diseases / R. Manfredi ... [et Al.] -- Ibd: Epidemiology And Risk Factors / G. Riegler, A. De Leone -- Inflammatory Bowel Disease: The Pathologists Approach To The Clinical Problem / E. Salmo, S. Absar, N. Haboubi -- Dysplasia In Inflammatory Bowel Disease: From Genetics To Treatment / E. Salmo, P. O'connolly, N. Haboubi -- Ibd: Cancer Risk And Surveillance / G. Riegler, I. Esposito -- Colonic And Anorectal Motility In Inflammatory Bowel Disease / B. Salvioli, G. Bazzocchi -- Extraintestinal Manifestations Of Inflammatory Bowel Disease / G. C. Sturniolo, M. Barollo, R. D'incà -- Perianal Crohn's Disease: Assessment With Endoanal Ultrasonography / G. A. Santoro ... [et Al.] -- Endoscopy In Crohn's Disease / A. Ederle ... [et Al.] -- Role Of Endoscopy In Ulcerative Colitis / G. Angelini, L. Bernardoni -- Nutrition And Malnutrition In Inflammatory Bowel Disease / I. Vantini ... [et Al.] --^ Probiotics In Inflammatory Bowel Diseases / P. Gionchetti ... [et Al.] -- Quality Of Life In Patients Undergoing Colorectal Surgery / M. Keighley -- Ibd And Pregnancy / G. Colucci, G. G. Delaini, F. Nifosì -- Urinary And Sexual Involvement In Ibd / L. Zorcolo, G. Casula -- Biological Approach In The Treatment Of Crohn's Disease / L. Frulloni ... [et Al.] -- Medical Therapy Of Fistulizing Crohn's Disease / L. Benini ... [et Al.] -- Surgical Options In Small-bowel Disease / G. G. Delaini, G. Colucci, F. Nifosì -- Crohn's Disease Of The Colon / A. Dziki -- Laparoscopy For The Treatment Of Crohn's Disease / A. D'annibale, E. Morpurgo -- Postoperative Prevention Of Relapse In Crohn's Disease / A. Keshava, D. C. C. Bartolo -- Surgical Treatment Of Perineal Crohn's Disease / B. Roche, J. Robert-yap -- Medical Treatment Of Ulcerative Colitis / F. De Iorio ... [et Al.] -- Indications For Surgical Treatment Of Ulcerative Colitis / Z. V. Krivokapic, G. I. Barisic --^ Surgical Management Of Acute Ulcerative Colitis / R. Tersigni, L. Alessandroni, R. Bertolini -- The Cancer Risk In Longstanding Ulcerative Colitis: Surveillance Colonoscopy And Prophylactic Surgery / L. Hultén -- Salvage Surgery After Restorative Proctocolectomy / F. Selvaggi ... [et Al.] -- Management Of The Difficult Ileal Pouch-anal Anastomosis And Temporary Ileostomy / S. Galandiuk -- Open Questions In Restorative Proctocolectomy / F. Nifosì ... [et Al.] -- Follow-up Of Restorative Proctocolectomy: Clinical Experience Of A Specialised Pouch Clinic / H. Tulchinsky ... [et Al.] -- Management Of Pouchitis / P. Gionchetti ... [et Al.] -- Bowel Transplantation For Inflammatory Bowel Disease / R. Margreiter -- Liver Transplantation For Primary Sclerosing Cholangitis And Inflammatory Bowel Disease / I. Königsrainer ... [et Al.] -- Emergent Issues And Future Trends In Familial Adenomatous Polyposis / G. G. Delaini ... [et Al.] --^ Genetic Mutations In Fap And Conventional Or Laparoscopic Surgical Approach / E. Contessini-avesani ... [et Al.] -- Clinical Significance Of Extra-colonic Manifestations Of Familial Adenomatous Polyposis / Y. Kariv, H. Tulchinsky, M. Rabau -- Desmoid Tumours In Familial Adenomatous Polyposis / F. Tonelli ... [et Al.] -- The Endoscopic Procedures In Familial Adenomatous Polyposis (fap):a Critical Review / W. Piubello, F. Bonfante, M. Tebaldi -- Fap History Through A Patient's Story / G. G. Delaini, G. Coucci, F. Nifosì -- Ileo-rectal Anastomosis Vs. Ileo-anal Pouch As The Surgical Treatment For Familial Adenomatous Polyposis / O. Aziz, P. Tekkis -- Surgery And Surveillance In Colon Polyposis Syndrome / T. Skřička -- Psyche And Colitis: What The Surgeon Should Know / M. Pescatori -- Interdisciplinary Management Of Inflammatory Bowel Diseases / M. Comberlato, F. Martin -- Interdisciplinary Management Of Familial Adenomatous Polyposis / M. Comberlato, F. Martin --^ Ileoanal Pouches And Indeterminate Colitis / G. Poggioli ... [et Al.] -- Quality Of Life In The Pouch Patient -- G. G. Delaini ... [et Al.] -- The Place Of Proctocolectomy With Ileostomy In The Era Of Restorative Proctocolectomy / G. Romano, F. Bianco, V. D'onofrio -- Surgical Management Of Ibd Emergencies: The Approach In A Peripheral Hospital / W. Thaler ... [et Al.] -- Management Of The Unhealed Perineal Wound / D. Segre ... [et Al.] -- Rehabilitation In Patients With Inflammatory Bowel Disease And Familial Adenomatous Polyposis / F. Lipanje, G. Colucci, G. G. Delaini. Gian Gaetano Delaini (ed.) ; Foreword By S.m. Goldberg. Includes Bibliographical References And Index. Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which the medical profession must face up to. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. In the near future, the aim will be to prevent these disorders and their sequelae through early detection and early intervention (for example genetic therapy). Unfortunately, we are still dealing with young patients with a lifelong disease course, leading to early morbidity (and in some cases mortality) and extended needs for medical treatment, with a consequent decrease in quality of life. IBD and FAP represent a challenge for a multidisciplinary medical approach where different personnel play major roles in different stages of the patient's treatment. This book represents the first action of the Rosa Gallo Foundation (a young lady affected by FAP, who died after multiorgan transplantation for intra-abdominal desmoid tumour) to improve management of this difficult condition, collecting and critically reviewing the many recent advancements on these topics. It is a reference not only for expert but also for all physicians who care for IBD and FAP patients. Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. The aim of the researchers will be to prevent these disorders through early detection and intervention, thanks to genetic therapy. This book gathers current methods of treatment of these diseases and also presents the management of their complications. Authors finally intend to give a comprehensive overview of the newer therapies to bring the readers up to date. Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. This book gathers current methods of treatment of these diseases and also presents the management of their complications. The authors give a comprehensive overview of the newer therapies to bring readers up to date.