Infective Endocarditis: Management In The Era Of Intravascular Devices (infectious Disease And Therapy)

The first up-to-date source on the subject in more than a decade, this authoritative and all-encompassing guide summarizes the latest findings on the epidemiology, pathogenesis, pathophysiology, clinical manifestations, diagnosis, and treatment of infective endocarditis. Written by a world recognized expert with more than 40 years of experience in the field, this reference focuses on the impact of staphylococci as causative organisms and their relationship to a variety of intravascular devices ranging from intravenous catheters to intracardiac defibrillators. Doody Review Services Reviewer: Adriana Maria Rosario, MD(Ochsner Clinic Foundation) Description: This is a complete review of infective endocarditis, covering all aspects of the disease from pathophysiology to therapeutic management. Purpose: This book reviews infective endocarditis, with a special emphasis on changes in epidemiology due to the increasing use of intra-cardiac devices. Infective endocarditis continues to be associated with significant morbidity and mortality, despite modern antibiotics and surgical treatment. This book explores the difficulties in the treatment of this disease as it relates to emerging pathogens and clinical profiles that have evolved with the proliferation of implanted biomechanical devices. Audience: The audience is very broad, including internists, cardiologists, intensivists, and infectious disease specialists, all of whom are frequently involved in the care of patients who have or are at risk for developing endocarditis. Features: A review of the different pathogens that are commonly associated with different patient populations is provided, along with an extensive description of the pathophysiology. Of special interest is the chapter on infective endocarditis associated with intracardiac devices and procedures, including a detailed description of the particular pathogenesis and microbiology. Also included is a chapter describing the mimics of endocarditis, well described conditions often mistaken for infective endocarditis, such as Marantic endocarditis, atrial myxoma, and systemic lupus. Clinical cases illustrate each of these different clinical entities and extensive references are provided with each chapter. Assessment: This is an excellent update on the current diagnosis and treatment of infective endocarditis. The author has an extensive clinical background and is well known in the field. The book constitutes an excellent up-to-date review of this challenging disease process. Front cover 1 Preface 10 Acknowledgment 12 Contents 14 Contributors 16 Chapter 1. Epidemiology 18 Chapter 2. Microbiology of Infective Endocarditis and Clinical Correlates: Gram-Positive Organisms 30 Chapter 3. Microbiology of Infective Endocarditis and Clinical Correlates: Gram-Negative and Other Organisms 68 Chapter 4. Pathology of Infective Endocarditis 118 Chapter 5. Pathoanatomical, Pathophysiological, and Clinical Correlations 136 Chapter 6. Clinical Manifestations of Native Valve Endocarditis 160 Chapter 7. Endocarditis in Intravenous Drug Abusers 184 Chapter 8. Prosthetic Valve Endocarditis 200 Chapter 9. Infective Endocarditis of Intracardiac Devices 220 Chapter 10. Nosocomial and Health Care-Associated Infective Endocarditis (Iatrogenic Infective Endocarditis) 228 Chapter 11. Infective Endocarditis of Immunocompromised Patients 248 Chapter 12. Diagnosis of Infective Endocarditis I 258 Chapter 13. Echocardiography 272 Chapter 14. Medical Management 290 Chapter 15. Surgical Treatment of Native Valve and Prosthetic Valve Infective Endocarditis 330 Chapter 16. Prophylaxis of Infective Endocarditis 348 Chapter 17. The Mimics of Endocarditis 362 Index 372 About the Editor 380