Infectious Agents Associated Cancers: Epidemiology and Molecular Biology (Advances in Experimental Medicine and Biology Book 1018)

"This book offers a state-of-the-art report on recent discoveries concerning viral, bacterial, and parasite infectious cancers. Cancer is one of the most common causes of death and diseases in human populations, and 15%-25% of human cancers in worldwide are considered to result from chronic infection by pathogens. Most oncology textbooks address genetic mutation, but not infectious agents such as viruses, bacteria and parasites. As such this book stimulates further research in the new area between cancers and chronic infection, and discusses the epidemiology and molecular biology of infectious causes of cancers. It also explores the prevention and treatment of infection-related cancers, and brings pathogenic research to the forefront in the never-ending endeavor to understand how pathogens maneuver and negotiate in a complex environment, including the micro/macro- environment of the human host. Further, it highlights the urgent need for a concerted program to develop vaccines and other diagnosis and interventions that will eventually help prevent and treat infectious cancers, and decrease their burden on human populations. It offers graduate students and researchers a comprehensive overview of the infectious causes of cancers"--Publisher's description Front Matter ....Pages i-xii Overview of Infectious Causes of Human Cancers (Qiliang Cai, Zhenghong Yuan)....Pages 1-9 Hepatitis B Virus-Associated Hepatocellular Carcinoma (Youhua Xie)....Pages 11-21 Human Papillomavirus-Related Cancers (Yanyun Li, Congjian Xu)....Pages 23-34 Merkel Cell Polyomavirus: A New DNA Virus Associated with Human Cancer (Margo MacDonald, Jianxin You)....Pages 35-56 Current Progress in EBV-Associated B-Cell Lymphomas (Yonggang Pei, Alexandria E. Lewis, Erle S. Robertson)....Pages 57-74 EBV Infection and Glucose Metabolism in Nasopharyngeal Carcinoma (Jun Zhang, Lin Jia, Chi Man Tsang, Sai Wah Tsao)....Pages 75-90 Kaposi’s Sarcoma-Associated Herpesvirus: Epidemiology and Molecular Biology (Shasha Li, Lei Bai, Jiazhen Dong, Rui Sun, Ke Lan)....Pages 91-127 Hepatitis C Virus-Associated Cancers (Zhigang Yi, Zhenghong Yuan)....Pages 129-146 Human T-Cell Leukemia Virus Type 1 Infection and Adult T-Cell Leukemia (Chi-Ping Chan, Kin-Hang Kok, Dong-Yan Jin)....Pages 147-166 Malignancies in HIV-Infected and AIDS Patients (Yongjia Ji, Hongzhou Lu)....Pages 167-179 Bacterial Infection and Associated Cancers (Caixia Zhu, Yuyan Wang, Cankun Cai, Qiliang Cai)....Pages 181-191 Parasite-Associated Cancers (Blood Flukes/Liver Flukes) (Meng Feng, Xunjia Cheng)....Pages 193-205 Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways (Xiaowen Yang, Zhijun Cheng, Lihua Zhang, Guiru Wu, Run Shi, Zhenxing Gao et al.)....Pages 207-224 Murine Gammaherpesvirus 68: A Small Animal Model for Gammaherpesvirus-Associated Diseases (Sihan Dong, J. Craig Forrest, Xiaozhen Liang)....Pages 225-236 Infection of KSHV and Interaction with HIV: The Bad Romance (Jie Qin, Chun Lu)....Pages 237-251 Interplay Between Microenvironmental Abnormalities and Infectious Agents in Tumorigenesis (Qing Zhu, Feng Gu, Caixia Zhu, Yuyan Wang, Fang Wei, Qiliang Cai)....Pages 253-271