Infection Control in the Intensive Care Unit, 2nd Edition (Topics in Anaesthesia and Critical Care)

Infection Control in the Intensive Care Unit has been entirely rewritten in this second edition. All statements are justified by the best available evidence, avoiding unsubstantiated expert opinion. The book contains a new section dedicated to the microbiology of the critically ill; specifically, how to process and interpret surveillance cultures to distinguish the ‘normal’ from the ‘abnormal’ carrier state. There are five totally new chapters dealing with evidence-based infection control molecular techniques for outbreak analysis; clinical virology in neonatal, paediatric and adult intensive care; the six basic principles of the therapy of an infection; and the role of the pharmacist in infection control. Attention is given to special topics such as nutrition, gut mucosal protection, and the control of antimicrobial resistance. The addition of enteral to parenteral antimicrobials contributes to the control of multi-resistant micro-organisms. This completely revised second edition is a must-have for anyone requiring in-depth knowledge in the ever expanding field of infection control. Cover ......Page 1 Preface......Page 6 Contents......Page 9 Contributors......Page 13 Authors’ Index......Page 19 1 Glossary of Terms and Definitions......Page 21 2 Carriage......Page 32 3 Colonization and Infection......Page 54 4 Classification of Micro-Organisms According to Their Pathogenicity......Page 66 5 Classification of ICU Infections......Page 78 6 Gut Microbiology - Surveillance Samples for the Detection of the Abnormal Carrier State......Page 89 7 Systemic Antibiotics......Page 105 8 Systemic Antifungals......Page 168 9 Enteral Antimicrobials......Page 184 10 Evidence-Based Infection Control in the Intensive Care Unit......Page 202 11 Device Policies......Page 223 12 Antibiotic Policies in the Intensive Care Unit......Page 241 13 Outbreaks of Infection in Intensive Care Units - Usefulness of Molecular Techniques for Outbreak Analysis......Page 257 14 Prevention of Infection Using Selective Decontamination of the Digestive Tract......Page 307 15 Lower Airway Infection......Page 324 16 Bloodstream Infections Including Endocarditis and Meningitis......Page 345 17 Infections of the Peritoneum Including Pancreas, Mediastinum, Pleura, Wounds, and Urinary Tract......Page 386 18 Infection on the Neonatal and Pediatric Intensive Care Units......Page 422 19 Immediate Adequate Antibiotics Control Morbidity and Mortality in Patients with Pancreatitis, Extensive Burns,Trauma, Exacerbated Chronic Obstructive Pulmonary Disease, or Liver Transplantation......Page 436 20 Intensive Care Unit Patients Following Transplantation......Page 462 21 Clinical Virology in NICU, PICU and Adult ICU......Page 476 22 AIDS Patients in the Intensive Care Unit......Page 501 23 Therapy of Infection......Page 520 24 SIRS, Sepsis, and MODS......Page 540 25 SIRS/Sepsis: Metabolic and Nutritional Changes and Treatment......Page 551 26 Gut Mucosal Protection in the Critically Ill Patient. Towards an Integrated Clinical Strategy......Page 567 27 Selective Decontamination of the Digestive Tract: the Role of the Pharmacist......Page 577 28 Antimicrobial Resistance - a Prospective 5-year Study......Page 595 29 ICU-Acquired Infection - Mortality, Morbidity, and Costs......Page 607 30 Evidence-Based Medicine in the Intensive Care Unit......Page 623 Subject Index......Page 637 This second edition of 'Infection control in the intensive care unit' has been completely rewritten. All statements are justified, where possible, by randomised controlled trials or meta-analyses, avoiding unsubstantiated expert opinion. The book contains a new section dedicated to the microbiology for the critically ill, in particular, how to process and interpret surveillance cultures to distinguish the 'normal' from the 'abnormal' carrier state. The usefulness of molecular techniques for outbreak analysis is discussed in a new chapter. An extensive chapter dedicated to clinical virology in neonatal, paediatric and adult intensive care units is also new, as well as the explanation of the six basic principles of the therapy of an infection. Attention is given to special topics such as nutrition, gut mucosal protection and the control of antimicrobial resistance. The addition of enteral to parenteral antimicrobials contributes to the control of multi-resistant micro-organisms "Infection Control in the Intensive Care Unit has been entirely rewritten in this second edition. All statements are justified by the best available evidence, avoiding unsubstantiated expert opinion. The book contains a new section dedicated to the microbiology of the critically ill, specifically, how to process and interpret surveillance cultures to distinguish the 'normal' from the 'abnormal' carrier state."--BOOK JACKET