Industrial Biocatalysis (Pan Stanford Series on Biocatalysis Book 1)

Biocatalysis has become an essential tool in the chemical industry and is the core of industrial biotechnology, also known as white biotechnology, making use of biocatalysts in terms of enzymes or whole cells in chemical processes as an alternative to chemical catalysts. This shift can be seen in the many areas of daily life where biocatalysts-with their environmentally friendly properties-are currently employed. Drivers are the big societal challenges resulting from concerns about the global climate change and the need for an assured energy supply. Modern biocatalysis relies to a large extent Content: 1. Biocatalysts : global market, industrial applications, aspects of biotransformation design, and societal challenges / Peter Grunwald -- 2. Making use of newly discovered enzymes and pathways : reaction and process development strategies for synthetic applications with recombinant whole-cell biocatalysts and metabolically engineered production strains / Daniel Meyer, Joerg Martin Buescher, and Juergen Eck -- 3. Directed evolution of enzymes for industrial biocatalysis / Youyun Liang, Ee Lui Ang, and Huimin Zhao -- 4. Strategies to overcome stability constraints in enzyme evolution and facilitate effective enzyme engineering / Stephane Emond, Raymond D. Socha, and Nobuhiko Tokuriki -- 5. Production of functional isoprenoids through pathway engineering / Jun-ichiro Hattan and Norihiko Misawa -- 6. Metabolic engineering for the biobased conversion of CO2 to biofuels / Jordan McEwen and Shota Atsumi -- 7. Mixed microbial cultures for industrial biotechnology : success, chance, and challenges / Wael Sabra and An-Ping Zeng -- 8. Extremophiles and their use in biofuel synthesis / Eldie Berger, Eloy Ferreras, Mark P. Taylor, and Don A. Cowan -- 9. Industrial applications of halophilic microorganisms / Aharon Oren -- 10. Non-pathogenic pseudomonas as platform for industrial biocatalysis / Till Tiso, Nick Wierckx, and Lars M. Blank -- 11. Use of corynebacterium glutamicum for the production of high-value chemicals from new carbon sources / Petra Peters-Wendisch and Volker F. Wendisch -- 12. Applications of enzymes in industrial biodiesel production / Jesper Brask, David Cowan, and Per Munk Nielsen 13. Promiscuous biocatalysts : applications for synthesis from laboratory to industrial scale / Qi Wu and Xian-Fu Lin -- 14. Micromagnetic porous and non-porous biocatalyst carriers / Julia Stolarow, Berna Gerçe, Christoph Syldatk, Ivana Magario, Christian Morhardt, Matthias Franzreb, and Rudolf Hausmann -- 15. Robust enzyme preparations for industrial application / Oliver Thum, Frank Hellmers, and Marion Ansorge-Schumacher -- 16. Hydrolases in non-conventional media : implications for industrial biocatalysis / Veronika Stepankova, Jiri Damborsky, and Radka Chaloupkova -- 17. Ene-reductases from cyanobacteria for industrial biocatalysis / Yilei Fu, Kathrin Castiglione, and Dirk Weuster-Botz -- 18. Cytochrome P450 biocatalysts : current applications and future prospects / Santosh Kumar -- 19. Laccases : green biocatalysts for greener applications / Susana Rodríguez-Couto -- 20. Lipase-catalyzed epoxidation of fatty compounds and alkenes / Fabian Haitz, Steffen Rupp, Thomas Hirth, and Susanne Zibek -- 21. Synthetic potential of dihydroxyacetone-utilizing aldolases / Anne K. Samland and Georg A. Sprenger -- 22. The hydantoinase process : recent developments for the production of non-canonical amino acids / Ulrike Engel, Jens Rudat, and Christoph Syldatk -- 23. Biotechnological approaches to dipeptide production / Martin Krehenbrink, Ahmed Sallam, and Alexander Steinbüchel -- 24. Synthetic enzyme cascades for valuable diols and amino alcohols : smart composition and optimization strategies / Torsten Sehl, Justyna Kulig, Robert Westphal, and Dörte Rother -- 25. Metabolic engineering for the biosynthesis of longevity molecules rapamycin and resveratrol / Victor M. Ye and Sujata K. Bhatia -- 26. Detergent proteases / Karl-Heinz Maurer -- 27. Industrial starch processing / Józef Synowiecki, Anna Panek, and Olga Pietrow -- 28. Algae : a rich source of energy and high-value products / Peter Grunwald -- 29. Enzyme-catalysed processes in a potential algal biorefinery / Bhavish Patel, Pongsathorn Dechatiwongse, and Klaus Hellgardt -- 30. Biocatalytic synthesis of polymers : a contribution to green chemistry / Karla A. Barrera-Rivera and Antonio Martinez-Richa -- 31. Bio-based chemicals and materials / Peter Grunwald. Cover 1 Contents 6 Preface 32 Chapter 1: Biocatalysts: Global Market, Industrial Applications, Aspects of Biotransformation Design, and Societal Challenges 38 Chapter 2: Making Use of Newly Discovered Enzymes and Pathways: Reaction and Process Development Strategies for Synthetic Applications with Recombinant Whole-Cell Biocatalysts and Metabolically Engineered Production Strains 70 Chapter 3: Directed Evolution of Enzymes for Industrial Biocatalysis 110 Chapter 4: Strategies to Overcome Stability Constraints in Enzyme Evolution and Facilitate Effective Enzyme Engineering 152 Chapter 5: Production of Functional Isoprenoids through Pathway Engineering 198 Chapter 6: Metabolic Engineering for the Biobased Conversion of CO2 to Biofuels 218 Chapter 7: Mixed Microbial Cultures for Industrial Biotechnology: Success, Chance, and Challenges 242 Chapter 8: Extremophiles and Their Use in Biofuel Synthesis 276 Chapter 9: Industrial Applications of Halophilic Microorganisms 320 Chapter 10: Non-Pathogenic Pseudomonas as Platform for Industrial Biocatalysis 360 Chapter 11: Use of Corynebacterium glutamicum for the Production of High-Value Chemicals from New Carbon Sources 410 Chapter 12: Applications of Enzymes in Industrial Biodiesel Production 454 Chapter 13: Promiscuous Biocatalysts: Applications for Synthesis from Laboratory to Industrial Scale 486 Chapter 14: Micromagnetic Porous and Non-Porous Biocatalyst Carriers 558 Chapter 15: Robust Enzyme Preparations for Industrial Application 590 Chapter 16: Hydrolases in Non-Conventional Media: Implications for Industrial Biocatalysis 620 Chapter 17: Ene-Reductases from Cyanobacteria for Industrial Biocatalysis 668 Chapter 18: Cytochrome P450 Biocatalysts: Current Applications and Future Prospects 700 Chapter 19: Laccases: Green Biocatalysts for Greener Applications 734 Chapter 20: Lipase-Catalyzed Epoxidation of Fatty Compounds and Alkenes 760 Chapter 21: Synthetic Potential of Dihydroxyacetone-Utilizing Aldolases 820 Chapter 22: The Hydantoinase Process: Recent Developments for the Production of Non-Canonical Amino Acids 854 Chapter 23: Biotechnological Approaches to Dipeptide Production 900 Chapter 24: Synthetic Enzyme Cascades for Valuable Diols and Amino Alcohols: Smart Composition and Optimization Strategies 924 Chapter 25: Metabolic Engineering for the Biosynthesis of Longevity Molecules Rapamycin and Resveratrol 968 Chapter 26: Detergent Proteases 986 Chapter 27: Industrial Starch Processing 1022 Chapter 28: Algae: A Rich Source of Energy and High-Value Products 1044 Chapter 29: Enzyme-Catalysed Processes in a Potential Algal Biorefinery 1102 Chapter 30: Biocatalytic Synthesis of Polymers: A Contribution to Green Chemistry 1138 Chapter 31: Bio-Based Chemicals and Materials 1164 Back Cover 1201