Individualized in-vitro fertilization : delivering precision fertility treatment

The increasing understanding of individual differences in response to in-vitro fertilization (IVF) treatment, resulting from genetic and ethnical differences, has increased the potential for individualized treatment for patients, resulting in improved pregnancy and live-birth outcomes. This illustrated book summarizes, and provides updates on, the most recent developments in individualized infertility treatment and embryo selection techniques. Individualization is not only confined to the different steps in the ovarian stimulation process and the luteal phase support, but also to embryo selection techniques, which include, among others, the analysis of embryo development pattern and genetic testing. Chapters cover a multitude of topics, ranging from oocyte maturation and immunological testing to fertilization technique in the IVF laboratory and preparation for optimal endometrial receptivity in cryo cycles. Essential reading for IVF specialists and embryologists in IVF Clinics and also an important text for medical consultants specializing in reproductive medicine, gynecology and embryology. Provides understanding of recent developments and updated techniques in infertility treatment/assisted reproductive techniques, including embryo selection techniques, to increase the chance of pregnancy Highlights the need for, and possibilities of, individualization in patients undergoing IVF treatment Detailed examination of each step in in-vitro fertilization (IVF) treatment allows the reader to re-evaluate possibilities in each treatment step "Despite the notion that the first baby, Louise Brown, was born in 1978 following IVF performed in a natural menstrual cycle, ovarian stimulation became the golden standard of care in clinical IVF, since the number of oocytes retrieved, is directly associated with pregnancy and life birth rates. The aim should be to titrate the stimulation in such a way that the optimal number of follicles develop. Too few follicles (also referred to as low response) usually means poor IVF outcome, whereas too many developing follicles induce a risk for developing OHSS and possibly reduce the chance of success with increasing number of oocytes, if stimulation is not adjusted towards the end of follicular phase"-- Provided by publisher Cover Title Copyright Contents Contributors 1 Individualized Ovarian Stimulation for Normal and High Responders 2 Individualized Ovarian Stimulation in Patients with Advanced Maternal Age and Premature Ovarian Aging 3 Individualized Oocyte Maturation 4 Individualized Luteal Phase Support 5 Individualized Management of Male Infertility 6 Individualized Fertilization Technique in the IVF Laboratory: IVF or ICSI? 7 Individualized Genetic Testing: Who Benefits? 8 Individualized Embryo Selection 9 Preparation for Optimal Endometrial Receptivity in Cryo Cycles 10 Individualized Immunological Testing in Recurrent Implantation Failure 11 Individualized Embryo Transfer Index An up-to-date guide to improving the outcomes of assisted reproductive technology by individualization of in-vitro fertilization (IVF) treatment during ovarian stimulation, in the IVF laboratory and embryo selection process. Designed for all specialists in reproductive medicine working in the field of IVF.