Immunotherapy with intravenous immunoglobulins : proceedings of a conference held at Interlaken, 6-9 May 1990

Acknowledgements; References; Discussion; Chapter 2. Intravenous immunoglobulin: mechanisms of action and their clinical application; Background; Thrombocytopenic purpura; Mononuclear phagocyte system blockade; Immune modulation; Discussion; Summary; References; Chapter 3. Hypothetic and established action mechanisms of therapy with immunoglobulin G; Introduction; Anti-infectious immunoglobulin G; Action mechanisms in chronic inflammatory diseases; Acknowledgement; References; Chapter 4. The distribution and catabolism of IVIG preparations in immunodeficient patients; Background. The use of intravenous human antibodies in the treatment of primary immunodeficiencies is well recognized. However, it is now evident that they also have therapeutic potential for a wide range of other clinical disorders. This book describes the use of human antibodies in the management of secondary (virus-induced) immunodeficiencies, neonatal and perinatal infections, and autoimmunity. Insight into their mechanism of action is also provided. Read more... Content: Front Matter , Page iii Copyright , Page iv Contributors , Pages v-xii Preface , Pages xix-xx , P. Imbach IVIG and regulation of autoimmunity through the idiotypic network , Pages 3-14 , G. DIETRICH, F. ROSSI, Y. SULTAN, S. KAVERI, U.E. NYDEGGER, M.D. KAZATCHKINE Intravenous immunoglobulin: mechanisms of action and their clinical application , Pages 15-25 , A.C. NEWLAND, M.G. MACEY, P.A. VEYS Hypothetic and established action mechanisms of therapy with immunoglobulin G , Pages 27-36 , URS E. NYDEGGER The distribution and catabolism of IVIG preparations in immunodeficient patients , Pages 37-45 , RALPH J. WEDGWOOD The home administration of IVIG in children with primary immunodeficiency , Pages 47-56 , ROGER H. KOBAYASHI, AI LAN D. KOBAYASHI, NAPOLEON LEE, SUSANNA FISCHER, HANS D. OCHS IVIG can save many preterm infants , Pages 59-64 , G. ROBERTO BURGIO Neonatal sepsis: an overview , Pages 65-74 , CAROL J. BAKER Immunoglobulin treatment and prophylaxis in the neonate , Pages 75-92 , A.G. UGAZIO, G. CHIRICO, M. DUSE, A. PLEBANI, L.D. NOTARANGELO, G. RONDINI, G.R. BURGIO Intravenous immunoglobulin in neonates: a decade of experience , Pages 93-101 , GERALD W. FISCHER, LEONARD E. WEISMAN Passive immunization for the protection of infants and young children from respiratory infection by respiratory syncytial virus , Pages 103-112 , VAL G. HEMMING, GREGORY A. PRINCE Use of immunoglobulin therapy in secondary antibody deficiencies , Pages 115-126 , E. RICHARD STIEHM Immunoprophylaxis in “septic-risk” patients undergoing surgery for gastrointestinal cancer. Preliminary results of a randomized, controlled, multicenter clinical trial , Pages 127-139 , FERDINANDO CAFIERO, MARCO GIPPONI Non-specific immunotherapy and intravenous gammaglobulin administration in surgical sepsis , Pages 141-147 , L. DOMINIONI, A. BENEVENTO, R. GENNARI, M.C. BESOZZI, M. HOURCADE, R. DIONIGI, M. ZANELLO Control of infection following major burns: the immunological approach , Pages 149-163 , ANDREW M. MUNSTER IVIG indication in patients with low-grade B-cell tumors , Pages 165-172 , HELEN CHAPEL, HELEN GRIFFITHS, MARTIN LEE Frequency and pathogenic implication of reactivated lymphotropic herpesviruses in autoimmune and immune deficiency disorders , Pages 173-192 , GERHARD R.F. KRUEGER, DHARAM V. ABLASHI, ALBERT RAMON, UWE LEMBKE Viruses and immunodeficiency , Pages 193-200 , A.D.B. WEBSTER, A. SA'ADU The role of IVIG in pediatric HIV infection , Pages 201-209 , URS B. SCHAAD Intravenous immunoglobulin in marrow transplantation , Pages 211-217 , NEENA KAPOOR Intravenous immunoglobulin for cytomegalovirus pneumonia , Pages 219-228 , GERALD ELFENBEIN, JEFFREY KRISCHER, JOHN GRAHAM-POLE, RICHARD HONG, JAN JANSEN, HILLARD LAZARUS, ELLIOT WINTON, RONALD BABINGTON The effect of prophylactic immune globulin on cytomegalovirus infection in liver transplants , Pages 229-235 , JOSEPH B. COFER, CHRISTINE A. MORRIS, BO S. HUSBERG, ROBERT M. GOLDSTEIN, THOMAS A. GONWA, GORAN B. KLINTMALM, WILLIAM L. SUTKER New clinical aspects of immune thrombocytopenic purpura (ITP) , Pages 239-243 , P. IMBACH Intravenous immunoglobulin: new aspects of mechanism of action in chronic ITP , Pages 245-252 , PETER BERCHTOLD, ROBERT McMILLAN Treatment effects on chronic idiopathic thrombocytopenia purpura , Pages 253-259 , JAMES B. BUSSEL Kawasaki disease and IVIG: what's going on here? , Pages 261-268 , STANFORD T. SHULMAN High-dose intravenous immunoglobulin therapy for insulin-dependent diabetes mellitus , Pages 269-282 , GARY M. LEONG, ZOE THAYER, GABRIEL ANTONY, STEPHEN COLAGIURI, JOHN DWYER, WARREN KIDSON, RICHARD FISHER, DENIS WAKEFIELD Effect of high-dose intravenous immunoglobulin in rheumatoid arthritis , Pages 283-295 , A. CORVETTA, M.M. LUCHETTI, G. POMPONIO, G. DANIELI, P.J. SPAETH Therapeutic opportunities in systemic vasculitis , Pages 297-306 , C.M. LOCKWOOD Ageing and autoimmunity: lessons learnt from the presence of autoantibodies in patients with malignant conditions , Pages 307-316 , YEHUDA SHOENFELD New concepts in the pathogenesis of allergies and asthma , Pages 319-331 , GARY L. LARSEN, BRUCE D. MAZER, ERWIN W. GELFAND Induction of immune tolerance in hemophiliacs with inhibitors, by combined treatment with IVIG, cyclophosphamide and factor VIII or IX–the Malmö model , Pages 333-344 , INGAMARIE NILSSON, ERIK BERNTORP Combined use of plasmapheresis and intravenous gammaglobulin in the treatment of HIV-positive and HIV-negative autoimmune syndromes , Pages 345-349 , RAPHAEL B. STRICKER, DOBRI D. KIPROV IVIG treatment in chronic inflammatory demyelinating polyneuropathy , Pages 351-358 , M. VERMEULEN, P.A. van DOORN, I. LUNDKVIST, A. BRAND Intravenous immunoglobulin in idiopathic inflammatory bowel disease: results of an open-label therapeutic trial , Pages 359-376 , HANS D. OCHS, SUSANNA H. FISCHER, DENNIS L. CHRISTIE, RODGER C. HAGGITT, DOUGLAS S. LEVINE The response of patients with chronic fatigue syndrome to intravenously administered gammaglobulin , Pages 377-386 , J.M. DWYER, A.R. LLOYD, I.B. HICKIE, D. WAKEFIELD, C.R. BOUGHTON Intravenously administered IgG for the treatment of thyroid eye disease , Pages 387-394 , J.M. DWYER, ELIZABETH M. BENSON, J.N. CURRIE, J. O'DAY The use of IVIG for the treatment of recurrent spontaneous abortion , Pages 395-400 , C. COULAM, A. PETERS, J. McINTYRE, W. FAULK Immunodeficiency in Down's syndrome , Pages 401-423 , A. FERRANTE, L.J. BEARD, Y.H. THONG, V. VUDDHAKUL, B. ROWAN-KELLY, D. GOH, G.T. MAI, R.K.S. LOH, S.C. HARTH, C. PEARSON, D. ROBERTON Maximizing the therapeutic potential of intravenously administered immunoglobulin G , Pages 427-432 , JOHN M. DWYER PRIMARY IMMUNODEFICIENCY , Pages 435-438 NEONATAL INFECTIONS , Pages 438-444 HIV INFECTION , Pages 444-446 TOLERABILITY AND SAFETY , Pages 446-448 SECONDARY IMMUNODEFICIENCY , Pages 448-453 AUTOIMMUNITY , Pages 453-461 MISCELLANEOUS , Pages 461-472 Index , Pages 473-484