Immunomodulation in Domestic Food Animals : Advances in Veterinary Science and Comparative Medicine

This volume amalgamates current knowledges of ''in vitro'' and ''in vivo'' use of immunomodulators in livestock. It includes rationale for their use, model systems, chemically-induced immunopotentiation, mechanism of action, cytokine therapy, modulation by nutrient supplementation, and neuro-endocrine immuno-interaction Content: Advances in Veterinary Science and Comparative Medicine Page ii Front Matter Page iii Copyright page Page iv Contributors Pages ix-x Foreword Pages xi-xii RONALD D. SCHULTZ Preface Page xiii FRANK BLECHA, BERNARD CHARLEY Rationale for Using Immunopotentiators in Domestic Food Animals Pages 3-19 FRANK BLECHA, BERNARD CHARLEY Model Systems to Study Immunomodulation in Domestic Food Animals Pages 21-41 JAMES A. ROTH, KEVAN P. FLAMING Mechanisms of Action of Some Immunomodulators Used in Veterinary Medicine Pages 43-99 P.J. QUINN Chemically Induced Immunomodulation in Domestic Food Animals Pages 103-119 MARCUS E. KEHRLI JR., JAMES A. ROTH Classical and New Approaches to Adjuvant Use in Domestic Food Animals Pages 121-160 KRISTIAN DALSGAARD, LUUK HILGERS, GÉRARD TROUVE A Thymosin–Tuftsin Conjugate as a New Potential Immunomodulator in Cattle Pages 161-177 DAVID NEMAT KHANSARI, PARVIZ JAFARI The Molecular Biology of Large Animal Cytokines Pages 181-213 CHARLES MALISZEWSKI, BYRON GALLIS, PAUL E. BAKER Interferon Immunomodulation in Domestic Food Animals Pages 215-230 H. BIELEFELDT-OHMANN, S.R. MARTINOD In Vivo Use of Interleukins in Domestic Food Animals Pages 231-252 FRANK BLECHA Nutritional Modulation of Immunity in Domestic Food Animals Pages 255-281 P.G. REDDY, R.A. FREY Neuroendocrine-Immune Interactions Pages 283-305 KEITH W. KELLEY, ROBERT DANTZER Potential for Improving Animal Health by Modulation of Behavior and Immune Function Pages 307-315 JOHN J. McGLONE Index Pages 317-334 Immunomodulation in Domestic Food Animals covers the developments in the immunology and regulation of the immune response in domestic food animals. This book is organized into four parts encompassing 12 chapters that describe numerous factors affecting an immune response of animals and the management of these factors for food animal production. Part I provides an overview of the basic concepts of immunomodulation and the rationale for manipulating the immune response in food animals. Part II contains information on immunopotentiation using chemicals and a thorough discussion of adjuvant use. The molecular biology and in vivo use of cytokines in food animals is presented in Part III. Lastly, Part IV discusses physiologically regulated immunomodulation, including nutritional modulation of the immune response and neuroendocrine-immune interactions. This book is of great value to immunologists, microbiologists, and feed scientists and researchers. This volume amalgamates current knowledges of "in vitro" and "in vivo" use of immunomodulators in livestock. It includes rationale for their use, model systems, chemical-induced immunopotentiation, mechanism of action and cytokine therapy.