Immunology of Infection (Immunology and Medicine, 25)

The immune system has evolved in large part to enable organisms to resist microbial infection. Microorganisms have long been used as experimental tools by immunologists, and the study of the immune response to viruses and bacteria has contributed much to our understanding of basic immunological mechanisms. There are also important practical and clinical reasons for attempting to understand the immunology of infections -- these include the rational design of vaccines, the pathogenesis of infectious diseases, the advent of AIDS, the rise in drug-resistant mycobacterial infections and the recognition of the infectious aetiology of peptic ulcer disease. The contributors to this book are all chosen for their active involvement and expertise in the fields. It bridges the divide between basic immunological research and clinical practice. Front Matter....Pages i-x Immunity to Bacteria....Pages 1-26 Molecular Structure and Immune Recognition of Mycobacteria....Pages 27-47 Immunology of Fungal Infections....Pages 49-85 The Immune Response to Virus Infection....Pages 87-98 The Immunology and Pathogenesis of Persistent Virus Infections....Pages 99-114 Immunopathology of HIV Infection....Pages 115-132 The Immunopathology of Viral and Bacterial Infections....Pages 133-157 The Pattern of Infection in Immunodeficiency....Pages 159-189 Immunoprophylaxis and Immunotherapy of Gram-negative Bacterial Infections....Pages 191-214 Current and Future Approaches to Vaccination Against Virus Diseases....Pages 215-233 Back Matter....Pages 235-245