Immunology and Drug Therapy of Allergic Skin Diseases (Progress in Inflammation Research)

Allergic skin diseases belong to the most common dermatoses. This book deals with fundamental (in particular immunological aspects) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases. Cells involved in the pathomechanisms of allergic skin disease are described in individual chapters. The allergic skin diseases which will be discussed are atopic dermatitis, being the chronic inflammatory skin disease with the highest prevalence, allergic contact dermatitis with special focus on contact dermatitis from cosmetics, being the most frequent cause of contact dermatitis and occupational contact dermatitis. The broad ethiology of urticaria and the value of several therapeutic strategies will be explained. The chapter on drug allergy will deal with the variety of symptoms and the difficulties concerning in vitro and in vivo diagnosis. The book is of great interest to clinicians working in the field of dermatology, allergology, pediatrics and even general practitioners... Allergic skin diseases belong to the most common dermatoses. This book deals with fundamental (in particular immunological aspects) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases. Cells involved in the pathomechanisms of allergic skin disease are described in individual chapters. The allergic skin diseases which will be discussed are atopic dermatitis, being the chronic inflammatory skin disease with the highest prevalence, allergic contact dermatitis with special focus on contact dermatitis from cosmetics, being the most frequent cause of contact dermatitis and occupational contact dermatitis. The broad ethiology of urticaria and the value of several therapeutic strategies will be explained. The chapter on drug allergy will deal with the variety of symptoms and the difficulties concerning in vitro and in vivo diagnosis. The book is of great interest to clinicians working in the field of dermatology, allergology, pediatrics and even general practitioners .. Front Matter....Pages i-ix Skin immune system (SIS)....Pages 1-13 Immunological aspects of allergic inflammation: IgE regulation....Pages 15-28 The role of T cells in the pathogenesis of atopic dermatitis....Pages 29-48 Immunological aspects of allergic inflammation: eosinophils....Pages 49-71 Mast cells....Pages 73-85 Cell-to-cell interactions....Pages 87-98 Atopic dermatitis....Pages 99-109 Allergic contact dermatitis: cosmetics....Pages 111-127 Clinical aspects of occupational contact dermatitis....Pages 129-135 Clinical aspects: urticaria....Pages 137-156 Clinical aspects: drug allergy....Pages 157-172 Future developments in treatment of atopic dermatitis....Pages 173-197 Back Matter....Pages 199-204