Immunology

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of ceHs and molecular moieties derived from those ceHs which constitute the RES. It may now be more fashionable in some quarters to consider these ceHs as part of what is caHed the mononuclear phagocytic system or the lymphoreticular system. Nev ertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge concerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as weIl as clinical areas including immu nopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is antic ipated that by presenting information concerning these apparently hetero geneous topics under the unifying umbreHa of the RES attention will be focused on the similarities as weIl as interactions among the ceH types constituting the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual volumes, are extremely grateful for the enthusiastic cooperation and enormous task under taken by members of the biomedical community in general and especially by members of the American as weIl as European and Japanese Reticuloendotheli~l Societies Front Matter....Pages i-xxiii Immunobiology of the Macrophage....Pages 1-11 The Role of Macrophages in Nonspecific Processes....Pages 13-26 The Functional Heterogeneity of Macrophages....Pages 27-42 Differentiation and Functional Regulation in Macrophage Cell Lines....Pages 43-66 Immune Functions of Dendritic-Type Cells....Pages 67-85 Utilization of Monoclonal Antibodies in the Characterization of Monocyte-Macrophage Differentiation Antigens....Pages 87-112 The Role of Mononuclear Phagocytes as Accessory Cells in Lymphocyte Responses....Pages 113-121 Role of the Reticuloendothelial System in T-Helper Cell Induction....Pages 123-140 The Role of Macrophages in the Processing and Presentation of Protein Antigens to T Lymphocytes....Pages 141-155 Requirement for Macrophages in Primary and Secondary Humoral Responses....Pages 157-171 Regulation of Macrophage Functions by Complement, Complement Receptors, and IgG-Fc Receptors....Pages 173-200 Antigen-Nonspecific Factors Elaborated by Macrophages Which Stimulate Lymphocytes....Pages 201-264 Lymphocyte Mediators That Modulate the Behavior of Macrophages....Pages 265-288 Role of Prostaglandins in Macrophage Cell Function....Pages 289-301 Monocyte-Mediated Antibody-Dependent Cellular Cytotoxicity....Pages 303-318 Role of Macrophages in Immunopotentiation by Adjuvants....Pages 319-337 Back Matter....Pages 339-347