Immunobiology (Principles of Medical Biology) (Vol 6)

As this volume demonstrates, immunobiology is a young science which is undergoing explosive growth. Judged by results, it is already an elaborate discipline which cuts across every other area in biomedical research and even has its own vocabolary (e.g., the "veto" effect). Rather than inculcate the habit of superficial learning by having the student go through a maze of details, we have sought to gather together sixteen essays that range from T-cells to psyhoneuroimmunology. This is keeping with the growing understanding that the student is expected to read and think far more for herself/himself. Next to nothing is known about innate immunity. However, recent evidence suggests that collections might bridge the gap between innate immunity and specific clonal immune responses. Collections are soluble effector proteins that include serum mannose-binding protein, and lung surfactants A and D. They are considered to be ante-antibodies Content: List of contributors Pages ix-xi Preface Page xiii E.Edward Bittar, Neville Bittar Chapter 1 The thymus in immunity Original Research Article Pages 1-20 J.F.A.P. Miller Chapter 2 The B-cell in immunity Original Research Article Pages 21-46 David Tarlinton Chapter 3 Cell-to-cell interactions in the immune system Original Research Article Pages 47-62 William A. Sewell, Ronald Penny Chapter 4 Immunological tolerance Original Research Article Pages 63-84 J.F.A.P. Miller Chapter 5 The generation of diversity in the immune system Original Research Article Pages 85-106 E.J. Steele, H.S. Rothenfluh Chapter 6 The antigen-antibody complex: Structure and recognition Original Research Article Pages 107-120 P.M. Colman Chapter 7 The major histocompatibility complex Original Research Article Pages 121-136 Brian D. Tait Chapter 8 B and T cell signaling at the molecular level Original Research Article Pages 137-150 Tomas Mustelin, Paul Burn Chapter 9 Cytokines in immunology Original Research Article Pages 151-169 Andrew J. Hapel, Shaun R. McColl Chapter 10 Activation and control of the complement system Original Research Article Pages 171-196 B. Paul Morgan Chapter 11 Phagocytes in immunity and inflammation Original Research Article Pages 197-229 Philip M. Murphy Chapter 12 Anaphylaxis Original Research Article Pages 231-238 Calman Prussin, Michael Kaliner Chapter 13 Autoimmunity and autoimmune disease Original Research Article Pages 239-263 Sudershan K. Bhatia, Noel R. Rose Chapter 14 Cell death and the immune system Original Research Article Pages 265-280 R.M. Kluck, J.W. Halliday Chapter 15 Designer antibodies Original Research Article Pages 281-302 Andy Minn, Jose Quintans Chapter 16 Psychoneuroimmunology Original Research Article Pages 303-313 Ruth M. Benca Index Pages 315-336 This volume covers such topics as the thymus in immunity, the B-cell in immunity, cell-to-cell interactions in the immune system, immunologic tolerance, the generation of diversity in immunology, the antigen-antibody complex, and the major histocompatibility complex.