Immune surveillance : proceedings of an international conference, held at Brook Lodge, Augusta, Michigan, May 11-13, 1970

Immune Surveillance deals with the issues regarding tumor immunology and surveillance, in which the central theme is all about the life span of the mammalian host that is depleted by the environment with mutagenic agents and solutions. The book is divided into six chapters. It includes discussions on the organization and modulation of cell membrane receptors, as well as the origin and expression of membrane antigens. It also covers the topics on the triggering mechanisms for and effector mechanisms activated by the cellular recognition. These topics analyze and evaluate alternatives for the recognition and destruction mechanisms in the knowledge of cell cooperation and requirements for immune recognition. A chapter provides discourse on a solution for the paradox of thriving tumors based on the demonstrable in vitro host immunity. Another discusses the generation of antibody diversity and the theory of self-tolerance. The last chapter explains the evaluation of the evidence for immune surveillance. This reference will be invaluable to those who specialize in immunology. Content: Front Matter , Page iii Copyright , Page iv CONFEREES , Pages ix-x PREFACE , Pages xi-xiii , Richard T. Smith, Maurice Landy INTRODUCTORY NOTE , Pages xv-xvi , Maurice Landy I - ORGANIZATION AND MODULATION OF CELL MEMBRANE RECEPTORS , Pages 1-82 II - TRIGGERING MECHANISMS FOR CELLULAR RECOGNITION , Pages 85-159 III - EFFECTOR MECHANISMS ACTIVATED BY CELLULAR RECOGNITION , Pages 161-259 IV - ROUTES OF ESCAPE FROM SURVEILLANCE , Pages 261-341 V - GENERATION OF ANTIBODY DIVERSITY AND SELF TOLERANCE – A NEW THEORY , Pages 343-435 VI - EVALUATION OF THE EVIDENCE FOR IMMUNE SURVEILLANCE , Pages 437-517 ABBREVIATIONS , Pages 519-520 AUTHOR INDEX , Pages 521-522 SUBJECT INDEX , Pages 523-536