Identifying and Estimating the Genetic Impact of Chemical Mutagens

Committee On Chemical Environmental Mutagens, Board On Toxicology And Environmental Health Hazards, Commission On Life Sciences, National Research Council. Includes Bibliographical References. And conclusions; Introduction; A primer on genetics, mutation, mutagens, and the implications of mutagenesis; Metabolism and pharmacologic disposition of mutagens and promutagens; The nature of test systems; Strategies for risk assessment: the choice and use of test systems to estimative human germinal mututation; Strategies for risk assessment: relation between mutation rate and human welfare; Testing and monitoring human populations; A mutagen assessment program; Some additional issues and research suggestions