Hormones, Metabolism and the Benefits of Exercise (Research and Perspectives in Endocrine Interactions)

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future. Front Matter ....Pages i-x Human Brown Adipose Tissue Plasticity: Hormonal and Environmental Manipulation (Francesco S. Celi)....Pages 1-11 The Energy Sensor AMPK: Adaptations to Exercise, Nutritional and Hormonal Signals (Benoit Viollet)....Pages 13-24 Plasma Steroids and Cardiorespiratory Fitness Response to Regular Exercise (Zihong He, Tuomo Rankinen, Arthur S. Leon, James S. Skinner, André Tchernof, Claude Bouchard)....Pages 25-42 Sending the Signal: Muscle Glycogen Availability as a Regulator of Training Adaptation (John A. Hawley)....Pages 43-55 Optimized Engagement of Macrophages and Satellite Cells in the Repair and Regeneration of Exercised Muscle (Regula Furrer, Christoph Handschin)....Pages 57-66 Skeletal Muscle microRNAs: Roles in Differentiation, Disease and Exercise (Rasmus J. O. Sjögren, Magnus H. L. Lindgren Niss, Anna Krook)....Pages 67-81 Tryptophan-Kynurenine Metabolites in Exercise and Mental Health (Paula Valente-Silva, Jorge Lira Ruas)....Pages 83-91 The Role of FNDC5/Irisin in the Nervous System and as a Mediator for Beneficial Effects of Exercise on the Brain (Mohammad Rashedul Islam, Michael F. Young, Christiane D. Wrann)....Pages 93-102 Civil Engineering; Natural Hazards; Geotechnical Engineering & Applied Earth Sciences Industry Sec; 2ECEES; Earthquake Engineering; Performance Based Design and Earthquake Engineering; Irregular Buildings and Earthquakes; Historical Structures and Earthquakes; Precast Buildings and Earthquakes; Bridge Design and Earthquakes Metabolic diseases; obesity; type 2 diabetes; muscle glycogen; skeletal muscle microRNAs; Tryptophan-kynurenine metabolites; FNDC5/irisin; AMPK; human brown adipose tissue plasticity