Histopathology of blistering diseases : with clinical, electron microscopic, immunological and molecular biological correlations : textbook and atlas

From the reviews: Histopathology of Blistering Diseases is one of my candidates for the medical book of the year. It combines superb technical qualities with excellent teaching, and addresses the most dramatic group of diseases encountered by dermatologists. My advice—glance through this book at a meeting or in the medical book store. Once you have it in your hands, you will buy it. Journal of the American Academy of Dermatology Dermatopathologen, Pathologen und alle an blasenbildenden Hauterkrankungen Interessierte werden an dem Buch ihre große Freude haben. JDDG (Journal der Deutschen Dermatologischen Gesellschaft) "As a practitioner in forensic pathology ... I have occasionally experienced a lack of information and reference sources ... when it comes to blistering diseases. Professor Mosaad Megahed ... clearly fills this gap ... . contains 1012 color figures that are of exceptional quality ... . brings all aspects of the current knowledge of blistering diseases together. It should be required reading for all those involved in histopathology and will prove invaluable for all forensic pathologists ... ." (Michael Tsokos, Forensic Science, Medicine, and Pathology, 2005) "Readable, easy to understand and ... comprehensive yet detailed review of all blistering disorders. The contents follow a logical progression through an excellent historical overview ... . a very sensible, clear and succinct classification of blistering diseases. ... a practical guide and reference for dermatologists, dermatopathologists and the general histopathologists. Scientists ... will also find it a useful reference source. ... a very handy resource for all professionals who require up to date information ... ." (Dr. WI Al-Daraji, ACP News – Spring, 2005) The book is a richly illustrated and comprehensive account of the histopathology of blistering diseases. Special emphasis is placed on the clinical features, immunofluorescence and electron microscopy. The new discoveries which have been made in the last years concerning the molecular biology, the molecular genetics as well as the immunology of these diseases are included. The reader of this unique book will find not only high quality histological and clinical photographs, presented in an elegant didactic way, but also abundant information about the recent developments. The book is designed for dermatologists, dermatopathologists, pathologists, medical students as well as scientists working in the field of blistering diseases. It is also of benefit for physicians confronted occasionally with this subject such as ophthalmologists and dentists Research into blistering diseases has been one of the Rona MacKie success stories of the last 20 years in dermatology. MD DSc FRCP FRCPath Blistering diseases divide naturally into the auto- Professor of Dermatology immune variants, seen mainly in adults, and inher- University of Glasgow ited varieties,mainly presenting in early childhood. Studies on all continents looking at the clinical - pects, traditional pathology, detailed electron - croscopy, and subsequent correlation of these three aspects with modern molecular biology have greatly increased our understanding of the mechanisms at faul. This textbook provides a detailed treatment of the histopathology of blistering diseases. In a succinct manner, it covers the clinical features, the immunofluorescence and the electron microscopic findings. It is supplemented by selected references and encompasses the new discoveries which occurred in recent years concerning the molecular aetiology of these diseases. It represents the first book in the field of blistering diseases which contains an in-depth account of histopathology and correlates it with the clinical features and the molecular biology in an unique didactic style. Front Matter....Pages I-XVI Front Matter....Pages 1-1 Historiography of Blistering Diseases....Pages 3-13 Front Matter....Pages 15-15 Ultrastructure and Molecular Anatomy of Desmosomes and the Cutaneous Basement Membrane Zone....Pages 17-45 Front Matter....Pages 47-47 Intraepidermal Blistering Diseases....Pages 49-153 Subepidermal Blistering Diseases....Pages 155-275 Diseases Occasionally or Frequently Associated with Blister Formation....Pages 277-346 Back Matter....Pages 347-405 Dealing with the histopathology of blistering diseases, this textbook covers the clinical features, the immunofluorescence, and the electron microscopic findings. It is supplemented by selected references and encompasses the various discoveries, which occurred over the years concerning the molecular etiology of these diseases.