Heredity And Visual Development (the Cell And Developmental Biology Of The Eye)

The eye has fascinated scientists from the earliest days of biological in­ vestigation. The diversity of its parts and the precision of their interaction make it a favorite model system for a variety of developmental studies. The eye is a particularly valuable experimental system not only because its tissues provide examples of fundamental processes, but also because it is a prominent and easily accessible structure at very early embryonic ages. In order to provide an open forum for investigators working on all aspects of ocular development, a series of symposia on ocular and visual devel­ opment was initiated in 1973. A major objective of the symposia has been to foster communication between the basic research worker and the clinical It is our feeling that much can be learned on both sides from community. this interaction. The idea for an informal meeting allowing maximum ex­ change of ideas originated with Dr. Leon Candeub, who supplied the nec­ essary driving force that made the series a reality. Each symposium has on a different aspect of ocular development. Speakers have concentrated been selected to approach related topics from different perspectives. Front Matter....Pages i-xi Mechanisms of Hereditary Visual Cell Disease....Pages 1-30 Sites of Gene Action in Rodents with Hereditary Retinal Degenerations....Pages 31-42 Neurofilaments in Retinas of Normal Mice and of Mice with Hereditary Photoreceptor Loss....Pages 43-62 Visual Abnormalities in Albino Mammals....Pages 63-83 Crystallins and Cataractogenesis: A Molecular Genetic Approach....Pages 85-100 Corneal Proteoglycan Biosynthesis and Macular Corneal Dystrophy....Pages 101-114 A Mechanistic Approach to the Inherited Retinal Dystrophies and the Role of Tissue Culture as an Investigative Probe....Pages 115-170 The Cellular Basis of Visual Dysfunction in Hereditary Retinal Disorders....Pages 171-204 Back Matter....Pages 205-214