Hematology in Clinical Practice, Fifth Edition (LANGE Clinical Medicine)

The most practical and efficient guide to the diagnosis and management of blood disorders – now in full color 200 full-color illustrations! Hematology in Clinical Practice is a succinct, cutting-edge guide to the diagnosis and treatment of disorders of red blood cells, white blood cells, and hemostasis, and the use of blood components for transfusion. Each disease state is discussed in detail, incorporating the pathophysiology, clinical features, up-to-date laboratory testing, and current management strategies into a comprehensive and practical approach to hematologic disorders. Features: New full-color presentation includes over 200 superb illustrations and classic images of blood morphology, tissue pathology, and clinical findings New Case Histories introduce and continue through relevant chapters, highlighting critical clinical points for diagnosis and management New end-of-chapter Points to Remember encapsulate key clinical information New chapters include Anemia in the Elderly and expanded and updated coverage of Transplantation and treatment of hematologic malignancies Outstanding collection of tables, charts, and illustrations that translate basic science into valuable clinical context Strong focus on practical clinical management and supportive care Coverage of state-of-the-art drugs and chemotherapies and the latest advances in genetic testing and molecular pathways Conveniently organized into sections on Red Cells, White Cells, Hemostasis, and Transfusion Medicine Title page......Page 4 Contents......Page 6 Preface......Page 8 Normal Erythropoiesis......Page 10 Clinical Approach to Anemia......Page 19 Marrow- Damage Anemia......Page 36 Anemias Associated with a Reduced Erythropoietin Response......Page 51 Iron-Deficiency Anemia......Page 62 Thalassemia......Page 74 Hemoglobinopathies .......Page 88 Macrocytic Anemias......Page 103 The Dysplastic and Sideroblastic Anemias......Page 118 Blood Loss Anemia......Page 133 Hemolytic Anemias......Page 145 Anemia in the Elderly......Page 164 Erythrocytosis and Polycythemia Vera......Page 172 Disorders of Porphyrin Metabolism......Page 185 Hemochromatosis......Page 191 Normal Myelopoiesis......Page 204 Quantitative and Qualitative Disorders of Neutrophils......Page 214 The Acute Myeloid Leukemias......Page 224 Chronic Myelogenous Leukemia and the Myeloproliferative Disorders......Page 238 Normal Lymphopoiesis and the Lymphatic System......Page 254 Lymphopenia and Immune Deficiency......Page 267 Chronic Lymphocytic Leukemia and Other Leukemic Lymphoproliferative Diseases ......Page 277 Non-Hodgkin Lymphomas......Page 288 Hodgkin Lymphoma......Page 310 Acute Lymphocytic Leukemia......Page 320 Plasma Cell Disorders......Page 328 Monocyte-Macrophage Disorders......Page 343 Normal Hemostasis......Page 350 Clinical Approach to Bleeding Disorders......Page 356 Vascular Purpura......Page 365 Thrombocytopenia......Page 373 Platelet Dysfunction and von Willebrand Disease......Page 393 Hemophilia and Other Intrinsic Pathway Defects......Page 407 Extrinsic and Common Pathway Coagulopathies......Page 420 Consumptive Coagulopathies......Page 429 Thrombotic Disorders......Page 437 Anticoagulation in the Management of Thrombotic Disorders......Page 456 Blood Component Therapy......Page 474 A ......Page 486 B ......Page 488 C ......Page 490 D ......Page 492 E ......Page 493 F ......Page 494 H ......Page 495 I ......Page 498 L ......Page 499 M ......Page 500 N ......Page 502 P ......Page 503 R ......Page 506 S ......Page 507 T ......Page 509 U ......Page 510 W ......Page 511 Z ......Page 512 Machine generated contents note: Part I: Red Blood Cell Disorders; Chapter 1. Normal Erythropoiesis; Chapter 2. Clinical Approach to Anemia; Chapter 3. Marrow-Damage Anemia; Chapter 4. Anemias Associated with a Reduced Erythropoietin Response; Chapter 5. Iron-Deficiency Anemia; Chapter 6. Thalassemia; Chapter 7. Hemoglobinopathies; Chapter 8. Macrocytic Anemias; Chapter 9. The Dysplastic and Sideroblastic Anemias; Chapter 10. Blood Loss Anemia; Chapter 11. Hemolytic Anemias; Chapter 12. Polycythemia; Chapter 13. Porphyrias; Chapter 14. Hemachromatosis; Part II: White Blood Cell Disorders; Chapter 15. Normal Myelopoiesis; Chapter 16. Quantitative and Qualitative Disorders of Neutrophils; Chapter 17. The Acute Myeloid Leukemias; Chapter 18. Myeloproliferative Disorders; Chapter 19. Normal Lymphopoiesis; Chapter 20. Lymphopenia and Immune Deficiency; Chapter 21. Chronic Lymphocytic Leukemias; Chapter 22. Non-Hodgkin's Lymphomas; Chapter 23. Hodgkin's Disease; Chapter 24. Acute Lymphocytic Leukemia; Chapter 25. Plasma Cell Disorders; Chapter 26. Macrophage Disorders; Part III: Disorders of Hemostasis; Chapter 27. Normal Hemostasis; Chapter 28. Clinical Approach to Bleeding Disorders; Chapter 29. Vascular Purpura; Chapter 30. Thrombocytopenia; Chapter 31. Platelet Dysfunction; Chapter 32. Hemophilia and Other Intrinsic Pathway Defects; Chapter 33. Extrinsic and Common Pathway Defects; Chapter 34. Consumptive Coagulopathies; Chapter 35. Thrombotic Disorders; Chapter 36. Anticoagulation in the Management of Thrombotic Disorders; Part IV: Transfusion Medicine; Chapter 37. Blood Component Therapy. "The most practical and efficient guide to the diagnosis and management of blood disorders, now in full color. Hematology in Clinical Practice is a succinct, cutting-edge guide to the diagnosis and treatment of disorders of red blood cells, white blood cells, and hemostasis, and the use of blood components for transfusion. Each disease state is discussed in detail, incorporating the pathophysiology, clinical features, up-to-date laboratory testing, and current management strategies into a comprehensive and practical approach to hematologic disorders. Features: New full-color presentation includes over 200 superb illustrations and classic images of blood morphology, tissue pathology, and clinical findings, new Case Histories introduce and continue through relevant chapters, highlighting critical clinical points for diagnosis and management, new end-of-chapter Points to Remember encapsulate key clinical information, new chapters include Anemia in the Elderly and expanded and updated coverage of Transplantation and treatment of hematologic malignancies, outstanding collection of tables, charts, and illustrations that translate basic science into valuable clinical context, strong focus on practical clinical management and supportive care, coverage of state-of-the-art drugs and chemotherapies and the latest advances in genetic testing and molecular pathways, conveniently organized into sections on Red Cells, White Cells, Hemostasis, and Transfusion Medicine."--Résumé de l'éditeur "A succinct, cutting-edge guide to the diagnosis and treatment of disorders of red blood cells, white blood cells, and hemostasis, and the use of blood components for transfusion. Each disease state is discussed in detail, incorporating the pathophysiology, clinical features, up-to-date laboratory testing, and current management strategies into a comprehensive and practical approach to hematologic disorders. New full-color presentation includes over 200 superb illustrations and classic images of blood morphology, tissue pathology, and clinical findings. Outstanding collection of tables, charts, and illustrations that translate basic science into valuable clinical context. Conveniently organized into sections on Red Cells, White Cells, Hemostasis, and Transfusion Medicine." -- Prové de l'editor