Head and Neck Pathology, A Volume in the Series: Foundations in Diagnostic Pathology, 3ED

An essential foundation text for residents and pathologists , the third edition of Head and Neck Pathology , a volume in the Foundations in Diagnostic Pathology series, has been fully revised to include recent advances in the field. Featuring a highly templated, easy-to-use format and new information throughout, this practical, affordable resource by Drs. Lester D. R. Thompson and Justin A. Bishop is ideal for study and review as well as everyday clinical practice . Inclusion of a wide range of diagnoses in both head and neck and endocrine organ pathology. A focus on the specific features of selected non-neoplastic and neoplastic entities, including broad and in-depth differential diagnoses. Clinical and Pathologic Features summarized in quick-reference boxes for fast access to information. A highly templated format that includes pertinent clinical, imaging, and management/prognostic features; pathologic features; ancillary studies; differential diagnosis; and meaningfully chosen bibliography. Over a thousand full-color photographs illustrate important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Contributions from internationally recognized expert pathologists, keeping you up to date with the latest information in the field. New criteria as established by the 2017 World Health Organization Classification of Head and Neck Tumours and the 2017 World Health Organization Classification of Endocrine Organ Tumours. A new oropharynx section, separated from the oral cavity. Inclusion of unique newly identified molecular information in many tumor entities. Coverage of NUT carcinoma, HPV-associated adenoid cystic-like carcinoma, sinonasal renal cell-like adenocarcinoma, SMARCB1 (INI-1) deficient sinonasal carcinoma, biphenotypic sinonasal sarcoma, neuroendocrine carcinomas, oropharyngeal carcinoma, polycystic disease and sclerosing polycystic adenosis, secretory carcinoma, cribriform adenocarcinoma of the minor salivary glands, variants of myoepithelioma, clear cell carcinoma, and changes in gnathic cysts classification. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices. Cover Head and Neck Pathology Other books in this series Copyright Page ■ Contributors ■ Foreword ■ Preface ■ Acknowledgments 1 Non-Neoplastic Lesions of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx ■ Rhinosinusitis Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Sinonasal Inflammatory Polyps Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Paranasal Sinus Mucocele Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Allergic Fungal Sinusitis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Nasal Glial Heterotopia Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Rhinoscleroma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Rhinosporidiosis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Granulomatosis With Polyangiitis Clinical Features Pathologic Features Gross Findings Microscopic Features Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Sinonasal Hamartomas Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Rhinosinusitis Sinonasal Inflammatory Polyps Paranasal Sinus Mucocele Glial Heterotopia Infections Granulomatosis With Polyangiitis (Wegener Granulomatosis) Sinonasal Hamartomas 2 Benign Neoplasms of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx ■ Sinonasal Papillomas Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Exophytic Papilloma Inverted Papilloma Oncocytic Cell Papilloma Ancillary Studies Immunohistochemical Findings Molecular Findings Differential Diagnosis Prognosis and Therapy ■ Lobular Capillary Hemangioma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Meningioma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Glomangiopericytoma (Sinonasal- Type Hemangiopericytoma) Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Genetic Findings Differential Diagnosis Prognosis and Therapy ■ Nasopharyngeal Angiofibroma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Ectopic Pituitary Adenoma Clinical Features Radiographic Features Pathologic Features Microscopic Findings Ancillary Studies Ultrastructural Findings Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Sinonasal Papillomas Lobular Capillary Hemangioma (Pyogenic Granuloma) Meningioma Glomangiopericytoma (Hemangiopericytoma) Nasopharyngeal Angiofibroma Pituitary Adenoma 3 Malignant Neoplasms of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx ■ Squamous Cell Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Sinonasal Adenocarcinoma Clinical Features Salivary Gland–Type Adenocarcinoma Non–Salivary Gland–Type Adenocarcinoma Pathologic Features Gross Findings Microscopic Findings Salivary Gland–Type Adenocarcinoma Non–Salivary Gland–Type Adenocarcinoma Intestinal-Type Adenocarcinoma. Nonintestinal-Type Adenocarcinoma. Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Sinonasal Undifferentiated Carcinoma (SNUC) Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Nut Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Nasopharyngeal Carcinoma Clinical Features Radiographic Features Laboratory Studies Pathologic Features Gross Findings Microscopic Findings Nonkeratinizing Squamous Cell Carcinoma Keratinizing Squamous Cell Carcinoma Basaloid Squamous Cell Carcinoma Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Mucosal Melanoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Olfactory Neuroblastoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Histochemistry Findings Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Extranodal NK/T-Cell Lymphoma, Nasal Type Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Histochemical Studies Immunohistochemical Findings Molecular Genetics Differential Diagnosis Prognosis and Therapy ■ Mesenchymal Malignancies Rhabdomyosarcoma Fibrosarcoma Biphenotypic Sinonasal Sarcoma Leiomyosarcoma Angiosarcoma ■ Ewing Sarcoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Histochemical Studies Immunohistochemical Findings Molecular Genetics Differential Diagnosis Prognosis and Therapy ■ Teratocarcinosarcoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Squamous Cell Carcinoma Sinonasal Adenocarcinoma Sinonasal Undifferentiated Carcinoma NUT Carcinoma Nasopharyngeal Carcinoma Malignant Mucosal Melanoma Olfactory Neuroblastoma Extranodal NK/T-Cell Lymphoma, Nasal Type Rhabdomyosarcoma Biphenotypic Sinonasal Sarcoma Fibrosarcoma Leiomyosarcoma Angiosarcoma Ewing Sarcoma Teratocarcinosarcoma 4 Non-Neoplastic Lesions of the Larynx, Hypopharynx, and Trachea ■ Vocal Cord Polyps and Nodules Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Contact Ulcer Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Amyloidosis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Special Stains Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Cysts of the Larynx (Including Laryngocele) Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Reactive Epithelial Changes Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Reading Suggested Reading Vocal Cord Polyps and Nodules Contact Ulcer Amyloidosis Cysts of the Larynx (Including Laryngocele) Reactive Epithelial Changes 5 Benign Neoplasms of the Larynx, Hypopharynx, and Trachea ■ Squamous Papillomas Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Granular Cell Tumor Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Adult Rhabdomyoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Chondroma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Inflammatory Myofibroblastic Tumor Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Squamous Papilloma/Papillomatosis Granular Cell Tumor Adult Rhabdomyoma Chondroma Inflammatory Myofibroblastic Tumor 6 Malignant Neoplasms of the Larynx, Hypopharynx, and Trachea ■ Precursor Squamous Lesions Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Squamous Cell Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy Variants of Squamous Cell Carcinoma Verrucous Squamous Cell Carcinoma Exophytic and Papillary Squamous Cell Carcinoma Spindle Cell Squamous Cell Carcinoma Basaloid Squamous Cell Carcinoma Adenosquamous Carcinoma ■ Neuroendocrine Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Chondrosarcoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Metastatic/Secondary Tumors Clinical Features Pathologic Features Microscopic Findings Differential Diagnosis Prognosis and Treatment Suggested Readings Suggested Readings Precursor Lesions Squamous Cell Carcinoma and Variants Neuroendocrine Carcinoma Chondrosarcoma Metastatic – Secondary Tumors 7 Non-Neoplastic Lesions of the Oral Cavity ■ Fordyce Granules Clinical Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Amalgam Tattoo Clinical Features Radiographic Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Ectopic Thyroid Clinical Features Radiographic Features Pathologic Features Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Oral Hairy Leukoplakia Clinical Features Pathologic Features Histochemical Studies Immunohistochemical Findings Molecular Studies Differential Diagnosis Prognosis and Therapy ■ Infections Clinical Features Pathologic Features Candida (Including Median Rhomboid Glossitis) Herpes Simplex Virus 1 Actinomycosis Differential Diagnosis Prognosis and Therapy ■ Oral Lichen Planus Clinical Features Pathologic Features Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Mucous Membrane Pemphigoid Clinical Features Pathologic Features Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Pemphigus Vulgaris Clinical Features Pathologic Features Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Recurrent Aphthous Stomatitis Clinical Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Traumatic Ulcerative Granuloma Clinical Features Pathologic Features Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Fordyce Granules Amalgam Tattoo Ectopic Thyroid Oral Hairy Leukoplakia Infections Oral Lichen Planus Mucous Membrane Pemphigoid Pemphigus Vulgaris Recurrent Aphthous Stomatitis Traumatic Ulcerative Granuloma 8 Benign Neoplasms of the Oral Cavity ■ Fibroma Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Squamous Papilloma (Including Verruca and Condyloma) Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Multifocal Epithelial Hyperplasia Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Lobular Capillary Hemangioma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Peripheral Ossifying Fibroma Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Peripheral Giant Cell Granuloma Clinical Features Radiographic Features Pathologic FFeatures Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Granular Cell Tumor Clinical FFeatures Pathologic FFeatures Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Congenital Granular Cell Epulis Clinical Features Pathologic FFeatures Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Ectomesenchymal Chondromyxoid Tumor Clinical FFeatures Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Fibroma Squamous Papilloma (Including Verruca and Condyloma) Multifocal Epithelial Hyperplasia Lobular Capillary Hemangioma Peripheral Ossifying Fibroma Peripheral Giant Cell Granuloma Granular Cell Tumor Congenital Epulis Ectomesenchymal Chondromyxoid Tumor 9 Malignant Neoplasms of the Oral Cavity ■ Squamous Cell Carcinoma Clinical Features Radiographic Features Pathologic Features Microscopic Findings Ancillary Studies Fine Needle Aspiration Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Kaposi Sarcoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Oral Mucosal Melanoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Squamous Cell Carcinoma Kaposi’s Sarcoma Oral Mucosal Melanoma 10 Malignant Neoplasms of the Oropharynx ■ Squamous Cell Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Fine Needle Aspiration Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Small Cell Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Squamous Cell Carcinoma Small Cell Carcinoma 11 Non-Neoplastic Lesions of the Salivary Glands ■ Developmental Lesions, Including Heterotopia and Oncocytosis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Histochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Mucus Retention Cyst, Mucocele, and Sialolithiasis Clinical Features Radiographic Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Necrotizing Sialometaplasia Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Lymphoepithelial Sialadenitis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Lymphoepithelial Cyst Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Sclerosing Polycystic Adenosis Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Intercalated Duct Hyperplasia Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Developmental Lesions, Including Heterotopia and Oncocytosis Mucus Retention Cyst, Mucocele, and Sialolithiasis Necrotizing Sialometaplasia Lymphoepithelial Sialadenitis Lymphoepithelial Cyst Sclerosing Polycystic Adenosis Intercalated Duct Hyperplasia 12 Benign Neoplasms of the Salivary Glands ■ Pleomorphic Adenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Basal Cell Adenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Canalicular Adenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Oncocytoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Histochemical Findings Ultrastructural Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Warthin Tumor Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Sebaceous Adenoma/Lymphadenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Hemangioma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Pleomorphic Adenoma Basal Cell Adenoma Canalicular Adenoma Oncocytoma Warthin Tumor Sebaceous Adenoma/Lymphadenoma Hemangioma 13 Malignant Neoplasms of the Salivary Glands ■ Mucoepidermoid Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Tumor Grading Ancillary Studies Immunohistochemical Findings Molecular Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Acinic Cell Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Adenoid Cystic Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Histochemical and Immunohistochemical Findings Molecular Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Polymorphous Adenocarcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Epithelial-Myoepithelial Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Secretory Carcinoma (Mammary Analogue Secretory Carcinoma) Clinical Features Pathologic Features Gross Findings Microscopic Findings Tumor Grading Ancillary Studies Immunohistochemical Findings Molecular Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Salivary Duct Carcinoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy ■ Carcinoma Ex Pleomorphic Adenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Extranodal Marginal Zone B-Cell Lymphoma of Salivary Glands Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Sialoblastoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Uncommon Carcinomas Basal Cell Adenocarcinoma Clear Cell Carcinoma Sebaceous Adenocarcinoma Oncocytic Carcinoma ■ Undifferentiated Carcinomas Small Cell Carcinoma Large Cell Carcinoma Lymphoepithelial Carcinoma ■ Adenocarcinoma, Not Otherwise Specified Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Fine Needle Aspiration Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Mucoepidermoid Carcinoma Acinic Cell Carcinoma Adenoid Cystic Carcinoma Polymorphous Adenocarcinoma Epithelial-Myoepithelial Carcinoma Secretory Carcinoma Salivary Duct Carcinoma Carcinoma ex Pleomorphic Adenoma Extranodal Marginal Zone B-Cell Lymphoma of Salivary Glands Sialoblastoma Uncommon Carcinomas Undifferentiated Carcinomas Adenocarcinoma Not Otherwise Specified 14 Non-Neoplastic Lesions of the Gnathic Bones ■ Osteomyelitis Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Dentigerous Cyst Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Periapical Cyst/Granuloma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Fibrous Dysplasia Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Osteonecrosis Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Simple (Solitary) Bone Cyst Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Nasopalatine Duct Cyst Clinical Features Radiographic Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Tori Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Cherubism Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Cemento-Osseous Dysplasia Clinical Features Radiograhic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Osteomyelitis Dentigerous Cyst Periapical Cyst/Granuloma Fibrous Dysplasia Osteonecrosis Nasopalatine Duct Cyst Simple Bone Cyst Tori Cherubism Osseous Dysplasia 15 Benign Neoplasms of the Gnathic Bones ■ Ossifying Fibroma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Juvenile Ossifying Fibroma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Central Odontogenic Fibroma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Osteoblastoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Osteoid Osteoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Cementoblastoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Ameloblastoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Odontogenic Keratocyst Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Calcifying Epithelial Odontogenic Tumor Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Adenomatoid Odontogenic Tumor Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Central Giant Cell Lesion Clinical Features Radiographic Features Pathologic Features Differential Diagnosis Prognosis and Therapy ■ Odontoma (Complex and Compound) Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Ossifying Fibroma Juvenile/Active Ossifying Fibroma Osteoblastoma Cementoblastoma Ameloblastoma Odontogenic Keratocyst Calcifying Epithelial Odontogenic Tumor Adenomatoid Odontogenic Tumor Central Giant Cell Lesion Odontoma 16 Malignant Neoplasms of the Gnathic Bones ■ Osteosarcoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Chondrosarcoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Mesenchymal Chondrosarcoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Ameloblastic Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Primary Intraosseous Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Sclerosing Odontogenic Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Clear Cell Odontogenic Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Ghost Cell Odontogenic Carcinoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Odontogenic Sarcoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Osteosarcoma Chondrosarcoma Mesenchymal Chondrosarcoma Ameloblastic Carcinoma Primary Intraosseous Carcinoma Sclerosing Odontogenic Carcinoma Clear Cell Odontogenic Carcinoma Ghost Cell Odontogenic Carcinoma Odontogenic Carcinosarcoma 17 Non-Neoplastic Lesions of the Ear and Temporal Bone ■ First Branchial Cleft Anomalies Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Cystic Chondromalacia Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Chondrodermatitis Nodular Helicis Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Angiolymphoid Hyperplasia With Eosinophilia Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Relapsing Polychondritis Clinical Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy ■ Cholesteatoma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Cholesterol Granuloma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings First Branchial Cleft Anomalies Cystic Chondromalacia Chondrodermatitis Nodular Helicis Angiolymphoid Hyperplasia With Eosinophilia Relapsing Polychondritis Cholesteatoma Cholesterol Granuloma 18 Benign Neoplasms of the Ear and Temporal Bone ■ Ceruminous Adenoma Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Langerhans Cell Histiocytosis Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Immunohistochemistry Molecular Findings Differential Diagnosis Prognosis and Therapy ■ Peripheral Nerve Sheath Tumor (Schwannoma) Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Genetic Studies Differential Diagnosis Prognosis and Therapy ■ Paraganglioma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Genetic Studies Differential Diagnosis Prognosis and Therapy ■ Meningioma Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential Diagnosis Prognosis and Therapy ■ Middle Ear Adenoma (Neuroendocrine Adenoma of the Middle Ear) Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Ultrastructural Findings Histochemical Findings Immunohistochemical Findings Differential Diagnosis Prognosis and Therapy ■ Endolymphatic Sac Tumor Clinical Features Radiographic Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Immunohistochemical Findings Genetic Studies Differential Diagnosis Prognosis and Therapy Suggested Readings Suggested Readings Ceruminous Adenoma Langerhans Cell Histiocytosis Peripheral Nerve Sheath Tumor (Schwannoma) Paraganglioma Meningioma Middle Ear Adenoma Endolymphatic Sac Tumor 19 Malignant Neoplasms of the Ear and Temporal Bone ■ Squamous Cell Carcinoma (External Auditory Canal and Middle Ear) Clinical Features Pathologic Features Gross Findings Microscopic Findings Ancillary Studies Differential An **essential foundation text for residents and pathologists**, the third edition of __Head and Neck Pathology__, a volume in the Foundations in Diagnostic Pathology series, has been fully revised to include recent advances in the field. Featuring a highly templated, easy-to-use format and new information throughout, this practical, affordable resource by Drs. Lester D. R. Thompson and Justin A. Bishop is **ideal for study and review** as well as **everyday clinical practice**. * Inclusion of a wide range of diagnoses in both head and neck and endocrine organ pathology. * A focus on the specific features of selected non-neoplastic and neoplastic entities, including broad and in-depth differential diagnoses. * Clinical and Pathologic Features summarized in quick-reference boxes for fast access to information. * A highly templated format that includes pertinent clinical, imaging, and management/prognostic features; pathologic features; ancillary studies; differential diagnosis; and meaningfully chosen bibliography. * Over a thousand full-color photographs illustrate important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. * Contributions from internationally recognized expert pathologists, keeping you up to date with the latest information in the field. * New criteria as established by the 2017 World Health Organization Classification of Head and Neck Tumours and the 2017 World Health Organization Classification of Endocrine Organ Tumours. * A new oropharynx section, separated from the oral cavity. * Inclusion of unique newly identified molecular information in many tumor entities. * Coverage of NUT carcinoma, HPV-associated adenoid cystic-like carcinoma, sinonasal renal cell-like adenocarcinoma, SMARCB1 (INI-1) deficient sinonasal carcinoma, biphenotypic sinonasal sarcoma, neuroendocrine carcinomas, oropharyngeal carcinoma, polycystic disease and sclerosing polycystic adenosis, secretory carcinoma, cribriform adenocarcinoma of the minor salivary glands, variants of myoepithelioma, clear cell carcinoma, and changes in gnathic cysts classification. * Expert ConsultT eBook version included with purchase. This **enhanced eBook experience** allows you to search all of the text, figures, and references from the book on a variety of devices.