Handbuch der experimentellen Pharmakologie Ergänzungs-Werk Bd. 4. General pharmacology / A. J. Clark-Edinburgh

Front Matter....Pages N3-VI Introduction....Pages 1-4 Methods of General Pharmacology....Pages 4-10 The Cell as a Physico-chemical System....Pages 10-17 General Characteristics of the Cell-Drug System....Pages 17-26 Reactions between Drugs and Active Proteins....Pages 26-31 The Action of Drugs on Catalysts and Enzymes....Pages 31-40 Action of Heavy Metals on Enzymes in vitro and in vivo....Pages 40-50 Action of Various Enzyme Poisons in vitro and in vivo....Pages 50-61 Concentration-action Relations I....Pages 61-79 Concentration-action Relations II....Pages 79-90 Quantitative Pharmacology and the Theory of Humoral Transmission....Pages 90-96 Kinetics of Drug Action....Pages 96-105 The Rate of Action of Drugs on Cells....Pages 105-123 Time-concentration Curves....Pages 123-142 Individual Variation of Response to Drugs....Pages 142-150 Relation Between Various Types of Curves Expressing Response of Cells to Drugs....Pages 150-165 Special Problems Relating to Variation of Populations....Pages 165-176 Quantitative Aspects of Drug Antagonism and of Drug Synergism....Pages 176-190 Qualitative Aspects of Drug Antagonism....Pages 190-199 Alternative Theories of Drug Action....Pages 199-206 Quantitative Aspects of Chemotherapy....Pages 206-215 Conclusion....Pages 215-217 Back Matter....Pages 218-228