Handbook of meningococcal disease : infection biology, vaccination, clinical management

A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts.As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field. Summarizes The Implications Of The Meningococcus Genome-sequencing Project, Emphasizing The Novel Strategies In Vaccine Development. Following A Look At The History, The Authors Go On To Treat The Epidemiology Of Meningococcal Disease, As Well As The Genetics, Structure And Function Of Virulence Factors. Further Chapters Cover Cross-talk Between Meningococci And Host Cells, Genomics And Immunobiology. Historical Aspects / Keith Cartwright -- The Population Biology Of Neisseria Meningitidis : Implications For Meningococcal Disease, Epidemiology And Control / Martin C.j. Maiden And Dominique A. Caugant -- Methods For Typing Of Meningococci / Keith A. Jolley ... [et Al.] -- Antibiotic Resistance / Colin Block And Julio A. Vázquez -- Neisseria Meningitidis Genome Sequencing Projects -- Phase Variation And Adaptive Strategies Of N. Meningitidis : Insights Into The Biology Of A Commensal And Pathogen / Peter M. Power And Richard Maxon -- Meningococcal Transformation And Dna Repair / Tonje Davidsen, Ole Herman Ambur And Tone Tønjum -- Structure And Genetics Of The Meningococcal Capsule / Matthias Frosch And Ulrich Vogel -- Genetics, Structure And Function Of Lipopolysaccharide / J. Claire Wright, Joyce S. Plested And E. Richard Moxon -- Major Outer Membrane Proteins Of Meningococci / Jeremy Derrick, John E. Heckels And Mumtax Virji --^ Iron Metabolism In Neisseria Meningitidis / Andrew Ekins And Anthony B. Schryvers -- Genetics, Structure And Function Of Pili / Philippe C. Morand And Thomas Rudel -- Mechanisms Of Attachment And Invasion / Sandrine Bourdoulous And Xavier Nassif -- Role Of Complement In Defense Against Meningococcal Infection / Sanjay Ram And Ulrich Vogel -- Cellular Immune Responses In Meningococcal Disease / Oliver Kurzai And Matthias Frosch -- Surrogates Of Protection / Ray Borrow And Elizabeth Miller -- Conjugate Vaccines / Neil Ravenscoft And Ian M. Feavers -- Outer Membrane Vesicle-based Meningococcal Vaccines / Jan T. Poolman ... [et Al.] -- Genome Mining And Reverse Vaccinology / Rosanna Leuzzi ... [et Al.] -- Vaccination For The Control Of The Meningococcal Disease : The Use Of Meningococcal Vaccines Of The Public Health Perspective / Elisabeth Miller, Mary Ramsay And Helen Campbell -- Pathogenesis And Pathophysiology Of Invasive Meningococcal Disease / Petter Brandtzaeg --^ Course Of Disease And Clinical Management / Andrew J. Pollard And Simon Nadel -- Public Health Management / James Stuart. Edited By Matthias Frosch And Martin C.j. Maiden. Includes Bibliographical References And Index. Also Available In An Electronic Version. Mode Of Access: World Wide Web. A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts.This volume uniquely summarizes the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology. The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field. booktext......Page 1 color plates......Page 28 booktext1......Page 45 booktext2......Page 58 booktext3......Page 78 booktext4......Page 94 booktext5......Page 116 booktext6......Page 138 booktext7......Page 158 booktext8......Page 183 booktext9......Page 201 booktext10......Page 218 booktext11......Page 253 booktext12......Page 271 booktext13......Page 291 booktext14......Page 308 booktext15......Page 329 booktext16......Page 355 booktext17......Page 375 booktext18......Page 402 booktext19......Page 422 booktext20......Page 434 booktext21......Page 455 booktext22......Page 510 booktext23......Page 547 index......Page 560 A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts. This volume uniquely summarizes the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and functio This is the third, revised and extended edition of theacknowledged ""Lectures on Quantum Optics"" by W. Vogel and D.-G. Welsch. It offers theoretical concepts of quantum optics, with special emphasis on current research trends. A unified concept of measurement-based nonclassicality and entanglement criteria and a unified approach to medium-assisted electromagnetic vacuum effects including Van der Waals and Casimir Forces are the main new topics that are included in the revised edition. The rigorous development of quantum optics in the context of quantum field theory and the attention to From basic research, to novel therapeutic strategies and clinical management, this work summarizes the implications of the meningococcus genome-sequencing project, emphasizing the strategies in vaccine development. It also looks at the epidemiology of meningococcal disease, as well as the genetics, structure, and function of virulence factors.