Handbook of Genomics and the Family: Psychosocial Context for Children and Adolescents (Issues in Clinical Child Psychology)

Today`s consumer can send a company a DNA sample and receive a detailed set of genetic test results in return all without ever visiting a health care provider. Although knowing one`s personal risk for serious disease may lead some individuals to make more informed health choices, an ever-growing set of questions remains: Are predictive genetic tests meaningful? Can the results be harmful as well as helpful? In what ways can genetic information be used by health care providers to predict disease risk and optimize medical management within concerned families? Most important, how might the landscape of genetic testing affect the care of children`s health? Although there are no easy answers, the Handbook of Genomics and the Family details in one authoritative volume the challenges entailed by the latest genetic advances and offers insights into the potential translation of this knowledge in pediatric and family practice and public health. This timely and comprehensive reference introduces readers to the study of how genes, singly and in combination with each other and the environment, affect health and behavior, summarizes current findings on genetics and genomics in disease etiology and prevention, and provides family-focused perspectives relating to genetic counseling and education. Key features of the Handbook include: - In-depth background in genetics and genomics in relationship to disease etiology and epidemiology. - Integrative frameworks for understanding genetics and genomics in the context of families. - Considerations for communicating genetic and genomic information. - Individual chapters on genetic and familial risks for specific diseases and conditions, including cancer, obesity, and Type 1 diabetes among children and adolescents. - Training, ethics, and other emerging issues and controversies. - Contemporary policies on genetic testing in children and families. The Handbook of Genomics and the Family is essential reading for clinical child and pediatric psychologists and psychiatrists, pediatricians and nurses, clinical geneticists and genetic counselors, and public health specialists as advances in genetics lead the way to more personalized models of health. TOC:The New Era of Genomics: Childhood and Society Revisited.- Key Concepts in Human Genomics and Molecular Biology.- Key Concepts in Human Genomics and Psychology.- Understanding Childhood Gene, Environment, and Gene x Environment Interaction Effects.- Goals, Process, and Content of Genetic Counseling: Applications to Children, Adolescents, and Their Families.- Genomics and the Family: Integrative Frameworks.- Potential Impact of Genomic Information on Parent-Child Relationships.- Potential Impact of Genomic Information on Childhood Sibling Relationships.- Family Communication of Genomic Information.- Developmental Perspectives on Health and Risk Communication: Theories and Applied Methodologies for Genomics.- Prenatal Diagnosis and Carrier Screening.- Single Gene Disorders: Cystic Fibrosis, Sickle Cell Disease, Duchenne`s Muscular Dystrophy and Others.- Cancer.- Diabetes.- Cardiovascular Disease.- Obesity.- Tobacco, Alcohol, and Other Risk Behaviors .- Childhood Psychiatric and Neurodevelopmental Genomics.- Bioethical Perspectives on Pediatric Gene Therapy and Pharmacogenomics.- Informed Consent and the Protection of Human Subjects in Genomic Research with Children, Adolescents, and Families .- Ethical, Legal, and Social Issues in the Genetic Testing of Minors.- National Policy Perspectives on Pediatric Genetic Testing.- Privacy and Insurance Issues in Pediatric Genetic Testing.- Training, Practice, and Collaboration: New Opportunities for Pediatric Psychology and Genomic Medicine.-Prevention and Control: Genes, Behavior, and Beyond Front Matter....Pages i-xxvii Front Matter....Pages 1-1 Key Concepts in Human Genomics and Epidemiology....Pages 3-31 Psychological Genetics: Understanding the Nature of Psychological Differences Through Etiology....Pages 33-55 Front Matter....Pages 57-57 Understanding Gene, Environment, and Gene × Environment Interaction Effects: The Example of Childhood Externalizing Disorders....Pages 59-86 Process in Genetic Counseling: Considerations for Children and Their Families....Pages 87-107 Genomics and the Family: Integrative Frameworks....Pages 109-139 Potential Impact of Genomic Information on Childhood Sibling Relationships....Pages 141-161 Family Communication of Genomic Information....Pages 163-189 Conveying Genetic Risk to Teenagers....Pages 191-217 Front Matter....Pages 219-219 Prenatal Screening and Diagnosis....Pages 221-240 Single Gene Disease Risk....Pages 241-266 Hereditary Cancer Risk....Pages 267-291 Type 1 Diabetes Risk....Pages 293-311 Cardiovascular Disease Risk....Pages 313-327 Obesity Risk....Pages 329-343 Tobacco and Alcohol Use Behaviors....Pages 345-367 Childhood Neuropsychiatric Risk....Pages 369-405 Genomic Risk Information for Common Health Conditions: Maximizing Kinship-Based Health Promotion....Pages 407-433 Front Matter....Pages 435-435 Pediatric Pharmacogenomics....Pages 437-456 Informed Consent and the Protection of Human Subjects in Genomic Research with Children and Families....Pages 457-483 Ethical, Legal and Social Issues in the Genetic Testing of Minors....Pages 485-521 Front Matter....Pages 435-435 Guidelines and Policies on Genetic Testing in Children and Families....Pages 523-557 Training, Practice, and Collaboration: New Opportunities for Pediatric Psychology and Genomic Medicine....Pages 559-575 Public Health Genomics....Pages 577-593 Back Matter....Pages 595-615