Handbook of Cardiac Anatomy, Physiology, and Devices (CURRENT CLINICAL ONCOLOGY)

Because of rapid growth in the medical device industry-which today enjoys revenues as large as those of the automobile industry-as well as in our understanding of cardiac disease processes, biomedical engineers must cope with a rising tide of highly complex information. In Handbook of Cardiac Anatomy, Physiology, and Devices, leading experts from the University of Minnesota's renowned Lillehei Heart Institute and scientists from Medtronic, Inc. have compiled a concise-yet detailed and comprehensive-reference source on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Here, active bioengineers working on cardiac devices will find the complete critical background they need to understand cardiac pacing, defibrillation, cardiac repair using stem cell therapy, robotics, less invasive cardiac surgery, biventricular pacing, cardiac bioenergetics, and more. Insightful chapters address animal models for cardiac research, cardiac mapping systems, heart valve disease, ventricular assist devices, and genomics-based tools and technology. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology, and Devices provides novice and expert biomedical engineers alike with the authoritative information and background they need to work on tomorrow's generaton of life-saving cardiac devices. General features of the cardiovascular system / Paul A. Iaizzo Cardiac development / Brad J. Martinsen and Jamie L. Lohr Anatomy of the thoracic wall, pulmonary cavities, and mediastinum Kenneth p. roberts and anthony j. weinhaus Anatomy of the human heart / Anthony J. Weinhaus and Kenneth P. Roberts Comparative cardiac anatomy / Alexander J. Hill and Paul A. Iaizzo The coronary system and associated medical devices / Ryan Lahm and Paul A. Iaizzo The pericardium / Edward Chinchoy, Michael Ujhelyi, Alexander Hill, Nicholas D. Skadsberg, and Paul A Iaizzo Cardiac myocytes / Vincent A. Barnett The cardiac conduction system / Timothy G. Laske and Paul A. Iaizzo Autonomic nervous system / Kevin Fitzgerald, Robert F. Wilson, and Paul A. Iaizzo Cardiac and vascular receptors and signal transduction / Daniel C. Sigg Reversible and irreversible damage of the myocardium: new ischemic syndromes, ischemia/reperfusion injury, and cardioprotection / James A. Coles Jr., Daniel C. Sigg, and Paul A. Iaizzo The effects of anesthetic agents on cardiac function / Michael K. Loushin Blood pressure, heart tones, and diagnoses / George Bojanov Ecg theory, 12-lead recordings, and their interpretation / Anthony Dupre, Sarah Vincent, and Paul A. Iaizzo Mechanical aspects of cardiac performance / Michael K. Loushin and Paul A. Iaizzo Energy metabolism in the normal and diseased heart / Arthur H. L. From and Robert J. Bache Introduction to echocardiography / Jamie L. Lohr Cardiac magnetic resonance imaging / Michael Jerosch-Herold, Ravi Teja Seethamraju, and Carsten Rickers Historical perspective of cardiovascular devices and techniques / Dee McManus, Monica A. Mahre, and Paul A. Iaizzo Animal models for cardiac research / Robert P. Gallegos, Andrew L. Rivard, and Richard W. Bianco Cardiac arrhythmias and transcatheter ablation / Fei L, Scott Sakaguchi, and David G. Benditt Pacing and defibrillation / Timothy G. Laske, Anna M. Legreid, and Paul A. Iaizzo Biventricular pacing for congestive heart failure / Fei L and Leslie W. Miller Cardiac mapping systems / Nicholas D. Skadsberg, Tim G. Laske, and Paul A. Iaizzo Cardiopulmonary bypass and cardioplegia / J. Ernesto Molina Heart valve disease / Robert P. Gallegos and R. Morton Bolman III Less invasive cardiac surgery / Kenneth K. Liao Treatment of cardiac septal defects: the evolution of the amplatzer(r) family of devices / John L. Bass End-stage cardiomyopathy: ventricular assist devices / Soon J. Park Experimental cell transplantation for myocardial repair / Joseph Lee, Atsushi Asakura, and Jianyi Zhang Genomics-based tools and technology / Jennifer L. Hall Emerging cardiac devices and technologies / Paul A. Iaizzo Index. Front Matter....Pages I-XIII Front Matter....Pages 1-1 General Features of the Cardiovascular System....Pages 3-11 Front Matter....Pages 13-13 Cardiac Development....Pages 15-23 Anatomy of the Thoracic Wall, Pulmonary Cavities, and Mediastinum....Pages 25-50 Anatomy of the Human Heart....Pages 51-79 Comparative Cardiac Anatomy....Pages 81-91 The Coronary System and Associated Medical Devices....Pages 93-100 The Pericardium....Pages 101-110 Front Matter....Pages 111-111 Cardiac Myocytes....Pages 113-121 The Cardiac Conduction System....Pages 123-136 Autonomic Nervous System....Pages 137-148 Cardiac and Vascular Receptors and Signal Transduction....Pages 149-159 Reversible and Irreversible Damage of the Myocardium....Pages 161-170 The Effects of Anesthetic Agents on Cardiac Function....Pages 171-180 Blood Pressure, Heart Tones, and Diagnoses....Pages 181-190 Basic ECG Theory, Recordings, and Interpretation....Pages 191-201 Mechanical Aspects of Cardiac Performance....Pages 203-222 Energy Metabolism in the Normal and Diseased Heart....Pages 223-239 Introduction to Echocardiography....Pages 241-248 Cardiac Magnetic Resonance Imaging....Pages 249-269 Front Matter....Pages 271-271 Historical Perspective of Cardiovascular Devices and Techniques....Pages 273-285 Front Matter....Pages 271-271 Animal Models for Cardiac Research....Pages 287-301 Cardiac Arrhythmias and Transcatheter Ablation....Pages 303-321 Pacing and Defibrillation....Pages 323-348 Biventricular Pacing for Congestive Heart Failure....Pages 349-359 Cardiac Mapping Systems....Pages 361-369 Cardiopulmonary Bypass and Cardioplegia....Pages 371-383 Heart Valve Disease....Pages 385-404 Less-Invasive Cardiac Surgery....Pages 405-411 Treatment of Cardiac Septal Defects....Pages 413-420 End-Stage Cardiomyopathy....Pages 421-426 Experimental Cell Transplantation for Myocardial Repair....Pages 427-438 Genomics-Based Tools and Technology....Pages 439-444 Emerging Cardiac Devices and Technologies....Pages 445-457 Back Matter....Pages 459-469 The Lillehei Heart Institute In Their Funding Of Illustrator Martin Finally, I Would Like To Thank My Family And Friends For Their Finch, Who Prepared Several Of The Original Figures; Gary Support Of My Career And Their Assistance Over The Years. Without Williams For His Computer Expertise And Assistance With Such Encouragement, I Would Not Have Even Dreamed Of Taking On Numerous Figures; William Gallagher And Charles Soule, Who Such An Ambitious Project. Specifically, I Would Like To Thank My Made Sure The Laboratory Kept Running Smoothly While Many Of Wife Marge, My Three Daughters, Maria, Jenna, And Hanna, My Us Were Busy Writing Or Editing; Dick Bianco For His Support Of Morn Irene, And Siblings, Mike, Chris, Mark, And Susan, For Always Our Lab And This Book Project; The Chairman Of The Department Being There For Me. On A Personal Note, Some Of My Motivation For Of Surgery, Dr. David Dunn, For His Support And Encouragement; Working On This Project Comes From The Memory Of My Father And The Biomedical Engineering Institute At The University Of Anthony, Who Succumbed To Sudden Cardiac Death At Too Early An Minnesota, Headed By Dr. Jeffrey Mccullough, Who Supported Age, And From The Positive Encouragement Of My Uncle Tom Halicki, This Project By Funding The Cardiovascular Physiology Interest Who Is Doing Well Seven Years After A Heart Transplant. Group (most Of Whose Members Contributed Chapters). Paul A. Laizzo, Phd Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V Blood Pressure, Heart Tones, And Diagnoses Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ix George Bojanov . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Because of rapid growth in the medical device industry-which today enjoys revenues as large as those of the automobile industry-as well as in our understanding of cardiac disease processes, biomedical engineers must cope with a rising tide of highly complex information. In Handbook of Cardiac Anatomy, Physiology, and Devices, leading experts from the University of Minnesota's renowned Lillehei Heart Institute and scientists from Medtronic, Inc. have compiled a concise-yet detailed and comprehensive-reference source on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Here, active bioengineers working on cardiac devices will find the complete critical background they need to understand cardiac pacing, defibrillation, cardiac repair using stem cell therapy, robotics, less invasive cardiac surgery, biventricular pacing, cardiac bioenergetics, and more. Insightful chapters address animal models for cardiac research, cardiac mapping systems, heart valve disease, ventricular assist devices, and genomics-based tools and technology. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology, and Devices provides novice and expert biomedical engineers alike with the authoritative information and background they need to work on tomorrow's generation of life-saving cardiac devices Leading experts from the University of Minnesota's renowned Lillehei Heart Institute and scientists from Medtronic, Inc., have assembled a concise yet detailed and comprehensive reference source of information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. The busy bioengineer working on cardiac devices will find here the complete critical background needed to understand cardiac pacing, defibrillation, cardiac repair using stem cell therapy, robotics, less invasive cardiac surgery, biventricular pacing, cardiac bioenergetics, and more. Insightful chapters address animal models for cardiac research, cardiac mapping systems, heart valve disease, ventricular assist devices, and genomics-based tools and technology. Two companion compact disks offer unique insights into the working heart Provides information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. This book describes cardiac pacing, defibrillation, cardiac repair using stem cell therapy, robotics, less invasive cardiac surgery, biventricular pacing, and, cardiac bioenergetics.