Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence (Nonserial publication)

These Guidelines review the use of medicines such as methadone, buprenorphine, naltrexone and clonidine in combination with psychosocial support in the treatment of people dependent on heroin or other opioids. Based on systematic reviews of the literature and using the GRADE approach to determining evidence quality, the guidelines contain specific recommendations on the range of issues faced in organizing treatment systems, managing treatment programmes and in treating people dependent on opioids.Developed in collaboration with internationally acclaimed experts from the different regions of the globe, this book should be of interest to policy makers, program managers, and clinicians everywhere who seek to alleviate the burden of opioid dependence. Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence (Nonserial publication)......Page 1 # ISBN-10 / ASIN: 9241547545 # ISBN-13 / EAN: 9789241547543......Page 4 Contents......Page 5 Acknowledgements......Page 8 Other contributors......Page 10 Abbreviations and acronyms......Page 13 Executive summary......Page 14 1 Scope and purpose......Page 23 2 Method of formulating recommendations......Page 25 3 Background......Page 27 4 Guidelines for health systems at national andsubnational levels......Page 30 5 Programme level guidelines – for programme managers and clinical leaders......Page 36 6 Patient level guidelines – for clinicians......Page 45 Annex 1 Evidence profiles......Page 77 Annex 2 Dispensing, dosing and prescriptions......Page 92 Annex 3 ICD-10 codes for conditions covered in theseguidelines......Page 93 Annex 4 Pharmacology of medicines available for thetreatment of opioid dependence......Page 94 Annex 5 Drug interactions involving methadone andbuprenorphine......Page 96 Annex 6 Alternatives for the treatment of opioid dependencenot included in the current guidelines......Page 99 Annex 7 Methadone and buprenorphine and internationaldrug control conventions......Page 100 Annex 8 Priorities for research......Page 104 Annex 9 Background papers prepared for technical expertmeetings to inform guideline development......Page 106 Annex 10 Opioid withdrawal scales......Page 107 Annex 11 Summary of characteristics of selected psychoactivesubstances......Page 111 Annex 12 Prescribing guidelines......Page 112 Annex 13 Glossary......Page 115 References......Page 118 Back Cover......Page 134 These guidelines review the use of medicines such as methadone, buprenorphine, naltrexone and clonidine in combination with psychosocial support in the treatment of people dependent on heroin or other opioids. Based on systematic reviews of the literature and using the GRADE approach to determining evidence quality, the guidelines contain specific recommendations on the range of issues faced in organizing treatment systems, managing treatment programs and in treating people dependent on opioids.--Publisher's description.