Growth, nutrition and metabolism of cells in culture. Vol. 3

Growth, Nutrition, and Metabolism of Cells in Culture, Volume 3, focuses on a number of specific, timely areas of research that make use of cell and tissue culture. The major theme of this volume is growth and its regulation in animal cells. The book includes studies on the role of growth factors in cell culture systems; the effects of cyclic nucleotides in cell proliferation in culture; metabolic regulation during the cell cycle; and the role of the cell surface in growth and metabolic regulation. There are also separate chapters on aspects of abnormal cell growth and metabolism; DNA repair; genetic analysis using cell fusion techniques; the growth of vascular cells in culture for atherosclerosis research; the culture of haploid vertebrate cells for genetic analysis of cell function; data on haploid cell culture; and the value of using cell cultures to test for the possible toxicity of various pharmacologic agents. Content: CONTRIBUTORS , Page ii Front Matter , Page iii Copyright , Page iv LIST OF CONTRIBUTORS , Pages ix-x PREFACE , Pages xi-xii , George H. Rothblat, Vincent J. Cristofalo CONTENTS OF OTHER VOLUMES , Pages xiii-xiv 1 - CELL, TISSUE, AND ORGANOID CULTURES OF BLOOD VESSELS , Pages 1-56 , George M. Martin, Charles E. Ogburn 2 - HAPLOID VERTEBRATE CELL CULTURES , Pages 57-82 , Liselotte Mezger-Freed 3 - CELL FUSION IN GENETIC ANALYSIS , Pages 83-107 , Carlo M. Croce 4 - THE STRUCTURAL AND FUNCTIONAL ROLES OF LIPIDS IN THE SURFACES OF ANIMAL CELLS GROWN IN VITRO , Pages 109-148 , Alan F. Horwitz 5 - METABOLIC REGULATION IN THE CELL CYCLE , Pages 149-196 , Robert R. Klevecz, Gerald L. Forrest 6 - DNA REPAIR IN CULTURED MAMMALIAN CELLS , Pages 197-224 , Jerry R. Williams, John B. Little 7 - CONTROL OF ANIMAL CELL PROLIFERATION , Pages 225-294 , H.L. Leffert, K.S. Koch 8 - CYCLIC NUCLEOTIDES , Pages 295-354 , Maynard H. Makman, Stephen A. Morris, Ho Sam Ahn 9 - VIRAL TRANSFORMATION OF CULTURED MAMMALIAN CELLS AS A MULTI-STEP PROCESS , Pages 355-419 , George P. Studzinski 10 - CHEMICAL CARCINOGENESIS IN VITRO , Pages 421-470 , Leila Diamond, William M. Baird 11 - TOXICITY TESTING IN VITRO , Pages 471-495 , Roland M. Nardone AUTHOR INDEX , Pages 497-537 SUBJECT INDEX , Pages 539-548