Glycoscience : chemistry and chemical biology I - III : with contributions by numerous experts ; [with CD-ROM] / [4] CD-ROM

Glycostructures play a pivotal and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Within recent years tools have been developed to promote the understanding of their highly complex functions and the associated chemistry and chemical biology, however, many facts still remain undiscovered. These days the area is experiencing a quantum jump . Therefore the Editors in collaboration with six responsible Section Editors completely revised and updated the 1st edition to give up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic survey. The texts are furnished by more than 2500 figures, chemical structures and reaction schemes (including more than 12,000 individual chemical reactions), and more than 9,000 references. In concept and content this Major Reference Work received an essential improvement and expansion. Whereas chapter 1, 2, 3, 7, 8, and 9 are updated, expanded and rearranged versions of the 1st edition, many new subchapters are included in the chapters on monosaccharides, oligosaccharides and polysaccharides. The importance of the saccharide metabolism as well as the involvement of complex glycostructures in biologically and medically relevant processes are considered by addition of two large totally newly conceived chapters. Further, another novel chapter featuring key technologies and tools for functional glycobiology is incorporated. Responsible for this major update are the Section Editors who solicited a large number of highly reputed new authors to cover the changes in the content and to write the major supplements.Note: The Kindle edition of this book does not include any CDs or DVDs. Glycoscience has become a term covering all sorts of activities and applications within or at the edge of carbohydrate research. Glycostructures play a highly diverse and crucial role in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them, but many facts still remain undiscovered. "All roads lead to carbohydrates ... we cannot do without them." (K.C. Nicolaou). Presently the field is experiencing a "quantum jump". Therefore the editors have drawn together in this three volume set plus an accompanying CD-ROM, the complete and up-to-date information on glycostructures, their chemistry and chemical biology, and present them in the form of a comprehensive and strictly systematic survey. Methodology oriented introductory chapters are followed by a homogeneous and systematic approach (occurrence, properties, synthesis, biosynthesis and degradation, chemical biology and medicine) arranged according to classes of glycostructures. The texts are furnished by 2.670 figures, chemical structures and reaction schemes (including more than 12.000 individual chemical reactions), and more than 9.000 references. The stimulating and readily accessible volumes of Glycoscience - Chemistry and Chemical Biology have been designed as the essential resource for both the experts in the field and the large community of investigators in fields like biomedicine, cancer research, pharmaceutical and biochemistry, biology, food science, agriculture or (bio- )engineering Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information. Bertram O. Fraser-reid, Kuniaki Tatsuta, Joachim Thiem (eds.) ; With Contributions By Numerous Experts. Includes Bibliographical References And Index. The shapes or conformations of carbohydrates strongly influence both their reactivity and their physical properties.