متابولیسم گلوکز در مغز (مرور بین‌المللی نوروبیولوژی، 51)

Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference. Key Features \* Serves as an essential reference on glucose metabolism in the brain \* Presents authoritative accounts by leading researchers in the field \* Includes thorough reviews with provocative sections on future directions Content: Editorial Board Page ii Contributors Pages xi-xii Preface Pages xiii-xiv Donard S. Dwyer Energy metabolism in the brain Review Article Pages 1-102,IN1-IN4 Leif Hertz, Gerald A. Dienel The cerebral glucose-fatty acid cycle: Evolutionary roots, regulation, and (patho)physiological importance Review Article Pages 103-158 Kurt Heininger Expression, regulation, and functional role of glucose transporters (GLUTs) in brain Review Article Pages 159-188 Donard S. Dwyer, Susan J. Vannucci, Ian A. Simpson Insulin-like growth factor-1 promotes neuronal glucose utilization during brain development and repair processes Review Article Pages 189-217,IN5-IN7 Carolyn A. Bondy, Clara M. Cheng CNS sensing and regulation of peripheral glucose levels Review Article Pages 219-258 Barry E. Levin, Ambrose A. Dunn-Meynell, Vanessa H. Routh Glucose transporter protein syndromes Review Article Pages 259-288,IN9-IN10 Darryl C. De Vivo, Dong Wang, Juan M. Pascual, Yuan Yuan Ho Glucose, stress, and hippocampal neuronal vulnerability Review Article Pages 289-324 Lawrence P. Reagan Glucose/mitochondria in neurological conditions Review Article Pages 325-376 John P. Blass Energy utilization in the ischemic/reperfused brain Review Article Pages 377-414 John W. Phillis, Michael H. O'Regan Diabetes mellitus and the central nervous system Review Article Pages 415-453 Anthony L. McCall Diabetes, the brain, and behavior: Is there a biological mechanism underlying the association between diabetes and depression? Review Article Pages 455-479 Alan M. Jacobson, Jacqueline A. Samson, Katie Weinger, Christopher M. Ryan Schizophrenia and diabetes Review Article Pages 481-501 David C. Henderson, Elissa R. Ettinger Psychoactive drugs affect glucose transport and the regulation of glucose metabolism Review Article Pages 503-530 Donard S. Dwyer, Timothy D. Ardizzone, Ronald J. Bradley Index Pages 531-546 Contents of recent volumes Pages 547-555 Energy metabolism in the brain / Leif Hertz and Gerald A. Dienel The cerebral glucose-fatty acid cycle: evolutionary roots, regulation, and (patho)physiological importance / Kurt Heininger Expression, regulation, and functional role of glucose transporters (GLUTs) in brain / Donard S. Dwyer, Susan J. Vannucci, and Ian A. Simpson Insulin-like growth factor-1 promotes neuronal glucose utilization during brain development and repair processes / Carolyn Bondy and Clara M. Cheng CNS sensing and regulation of peripheral glucose levels / Barry E. Levin, Ambrose A. Cunn-Meynell, and Vanessa H. Routh Glucose transporter protein syndromes / Darryl C. De Vivo ... [et al.] Glucose, stress, and hippocampal neuronal vulnerability / Lawrence P. Reagan Glucose/mitochondria in neurological conditions / John P. Blass Energy utilization in the ischemic/reperfused brain / John W. Phillis and Michael H. O'Regan Diabetes mellitus and the central nervous system / Anthony L. McCall Diabetes, the brain, and behavior: is there a biological mechanism underlying the association between diabetes and depression? / Alan M. Jacobson ... [et al.] Schizophrenia and diabetes / David C. Henderson and Elisa R. Ettinger Psychoactive drugs affect glucose transport and the regulation of glucose metabolism / Donard S. Dwyer, Timothy D. Ardizzone, and Ronald J. Bradley. Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an important role in diseases such as diabetes, stroke, schizophrenia and drug abuse as well as in normal and dysfunctional memory and cognition. This volume represents a thorough examination of all the major issues that are relevant to glucose metabolism by brain cells in relation to disease, combining basic research and clinical findings in a single, indispensable reference.

Key Features
* Serves as an essential reference on glucose metabolism in the brain
* Presents authoritative accounts by leading researchers in the field
* Includes thorough reviews with provocative sections on future directions Studies of glucose metabolism in the brain reflect a dichotomy due to the fact that the complex, integrating functions of the brain can only be studied in the intact, functioning brain in the conscious individual (human or animal), whereas properties of brain cells, cell-cell interactions, and mechanisms are most readily evaluated in vitro under controlled conditions using brain slices, subcellular fractions or purified, isolated cells of different types.