Glial neuronal communication in development and regeneration [proceedings of the NATO Advanced Research Workshop on Glial Neuronal Communication in Development and Regeneration held at Castle Ringberg, Bavaria, FRG, June 9 - 15, 1985

This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals". The book reflects the outcome of an NATO work­ shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compa­ rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers must remain rather superficial and, of course, rather subjective. To simplify the issue, the question of publication can be narrowed down to two fac­ tors - the financial risk, undertaken by the publisher, and the scientific risk, borne by the editor. If the book is good (with respect to lay-out and content) it will be a success - nothing will be lost­ the people involved will enhance their reputation! We are left with the question of the usefulness of workshops. Without doubt, it is indeed a useful procedure for experts to come together, in an atmosphere of harmony, and freedom from external pressures and time limitations, to discuss a well-defined theme. Wether in agreement or disagreement, a fair and open forum can be expectet for a variety of contributions. Front Matter....Pages I-XX Front Matter....Pages 1-1 From Neuroepithelium to Mature Astrocytes....Pages 3-25 Experimental Models for Astrocyte Activation and Fibrous Gliosis....Pages 27-40 Microglia in Culture....Pages 41-51 Molecular Properties of Peripheral Glia....Pages 53-62 Front Matter....Pages 63-63 Adrenergic- and Histamine-Receptors on Cultured Astrocytes: Electrophysiological and Autoradiographic Binding Studies....Pages 65-79 Desipramine Treated C 6 Glioma Cells Express Opiate Receptors; Unmasking or Induction?....Pages 81-89 Expression of Recognition Molecules in the Cerebellum of Young and Adult Rats....Pages 91-104 Myelin-Associated Glycoprotein (MAG) in Chicken Neuronal Crest Derivatives, Including Neurons....Pages 105-115 Neurone-Glia Relationship in the Retina: Localization of GABA Uptake and Endogenous GFAP and GABA Immunoreactivities....Pages 117-129 Developmentally Regulated Glial and Neuronal Antigens Detected by Monoclonal Antibodies....Pages 131-144 Front Matter....Pages 145-145 Biosynthesis of the Neural Cell Adhesion Molecule (N-CAM) Glial, Muscle and Neuronal Forms of N-CAM Studied in Primary Rat Cell Cultures....Pages 147-157 Neurite Outgrowth Induced by Adhesive Proteins....Pages 159-181 Neuronal Adhesion to Components of the Extracellular Matrix and Control of Nerve Fiber Growth....Pages 183-207 Front Matter....Pages 209-209 Modulation by Neuronal Signals of Energy Substrate in the Glial Cells of Leech Segmental Ganglia....Pages 211-229 Regulation of Astrocytic High Affinity Uptake of Transmitter Amino Acids by Neuronal Signaling....Pages 231-245 Characterization of Glial Proteins Transferred into the Squid Giant Axon....Pages 247-261 Do Glial Cells Compete with Afferent Fibers for Apposition to the Neuronal Surface in Development and Aging of the Nervous System? A Study in the Avian Ciliary Ganglion with References to other Neurons....Pages 263-282 Front Matter....Pages 283-283 Factors Affecting the Survival and Maturation of Nerve Cells in Culture....Pages 285-302 Glycoconjugate Metabolism, Accretion and Release During Neurite Outgrowth in Normal and Transformed Cells of Neuronal Origin....Pages 303-321 In Vitro Analysis of Glial-Neuronal Communication During Cerebellum Ontogenesis....Pages 323-338 Front Matter....Pages 283-283 Effect of Nerve Growth Factor and cAMP Analogues on Neuronal Differentiation in PC12 Cells: Studies with an Inhibitor of cAMP-Dependent Protein Kinases....Pages 339-354 Are Phosphotyrosine-Containing Proteins Induced by Nerve Growth Factor Stimulation of PC12cells?....Pages 355-364 Chromaffin Cells: Modified Neurons that are Both Targets and Storage Sites of Neuronotrophic and Neurite Promoting Factors....Pages 365-384 Neurotrophic and Neurite Promoting Activities in Astroglial Conditioned Medium....Pages 385-406 Neurite-Promoting Factors for Spinal Neurons....Pages 407-417 Putative Autoregulative Growth Factor in Conditioned Medium of Serum-Free Grown Astrocytes....Pages 419-432 Differentiation of Astrocyte Precursors from Mouse Cerebellum....Pages 433-449 Isolation of Two Astroglial Growth Factors From Bovine Brain; Comparison with Other Growth Factors; Cellular Localization....Pages 451-478 Glial Cell Development and Reactivity in Reaggregating Brain Cell Culture....Pages 479-489 Trophic and Metabolic Couplings Between Astroglia and Neurons....Pages 491-504 Front Matter....Pages 505-505 Neural Tissue Transplants Modify Response of the Immature Spinal Cord to Damage....Pages 507-528 Conditions for Neuronal Survival and Growth as Assessed by the Intracerebral Transplantation Technique in Lesion Models of the Adult CNS....Pages 529-544 Hippocampal Transplants: Synaptic Organization, their Use in Repair of Neuronal Circuits and Mouse to Rat Xenografting....Pages 545-564 A Model of Neuronal Sprouting for Examining the Role of Glia in Axonal Growth....Pages 565-573 Comparative Studies of the Astrocytic Membrane in Regenerative and Non-Regenerative Central Nervous Systems....Pages 575-583 Neural Tissue Transplants: Studies Using Tissue Culture Manipulations, Cell Marking Techniques and a Plasma Clot Method to Follow Development of Grafted Neurons and Glia....Pages 585-603 Pharmacologic and Immunologic Approaches to the Problems of Posttraumatic Glial Proliferation Following CNS Damage....Pages 605-628 Molecular Approach to the Role of Macrophages and Astrocytes in Nerve Growth and Regeneration....Pages 629-640 Culturing of Neurons and Oligodendrocytes Bulk Isolated from the Same Brain of Young Adult Rats....Pages 641-662 Front Matter....Pages 663-663 Role of Galactocerebroside in the Formation of Peripheral Myelin....Pages 665-681 Front Matter....Pages 663-663 Further Characterization of the Neuronal Cell Surface Protein Mitogenic for Schwann Cells....Pages 683-698 Galactocerebroside Expression by Non-Myelin Forming Schwann Cells....Pages 699-707 Molecular Organization of the Cell Membrane in Normal and Pathological Axons: Relation to Glial Contact....Pages 709-736 Oligodendrocyte Differentiation: Quantitative Studies in Primary Cultures of Dissociated Fetal Rat Brain....Pages 737-754 Myelin Palingenesis: The Reformation of Myelin by Mature Oligodendrocytes in the Absence of Neurons....Pages 755-777 Oligodendrocytes Ensheath Carbon Fibres and Produce Myelin in Vitro ....Pages 779-798 Oligodendrocyte Proliferation: Its Relationship to Central Nervous System Remyelination....Pages 799-816 Myelination in the Mouse by Transplanted Oligodendrocytes....Pages 817-830 Back Matter....Pages 831-867 This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals". The book reflects the outcome of an NATO workƯ shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compaƯ rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers must remain rather superficial and, of course, rather subjective. To simplify the issue, the question of publication can be narrowed down to two facƯ tors - the financial risk, undertaken by the publisher, and the scientific risk, borne by the editor. If the book is good (with respect to lay-out and content) it will be a success - nothing will be lostƯ the people involved will enhance their reputation! We are left with the question of the usefulness of workshops. Without doubt, it is indeed a useful procedure for experts to come together, in an atmosphere of harmony, and freedom from external pressures and time limitations, to discuss a well-defined theme. Wether in agreement or disagreement, a fair and open forum can be expectet for a variety of contributions Proceedings of the NATO Advanced Workshop on Glial-Neuronal Communication in Development and Regeneration held at Castle Ringberg, Bavaria, FRG, June 9-15, 1985