General Principles of Tumor Immunotherapy : Basic and Clinical Applications of Tumor Immunology

"General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world’s leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens. Front Matter....Pages I-XII Front Matter....Pages 1-1 A Perspective on Cancer Immunology and Immunotherapy....Pages 3-15 Tumor Antigens....Pages 17-31 T Cells and Antigen Recognition....Pages 33-53 The Role of Natural Killer T cells in Tumor Immunity....Pages 55-66 Immunomodulatory Molecules of the Immune System....Pages 67-121 HLA Class I Antigen Abnormalities in Tumors....Pages 123-144 The Local Tumor Microenvironment....Pages 145-167 Front Matter....Pages 169-169 Peptide and Protein Vaccines for Cancer....Pages 171-192 DNA Vaccines Against Cancer....Pages 193-215 Recombinant Viral and Bacterial Vaccines....Pages 217-250 Dendritic Cell Vaccines....Pages 251-274 Whole Cell Vaccines....Pages 275-295 Carbohydrate Vaccines Against Cancer....Pages 297-317 Front Matter....Pages 319-319 Monoclonal Antibody Therapy of Cancer....Pages 321-342 Adoptive Cellular Therapy for the Treatment of Cancer....Pages 343-361 Checkpoint Blockade and Combinatorial Immunotherapies....Pages 363-390 Front Matter....Pages 391-391 General Approaches to Measuring Immune Responses....Pages 393-404 Interferon Therapy....Pages 405-430 High Dose Interleukin-2 Therapy....Pages 431-452 Monoclonal Antibodies in Cancer Therapy....Pages 453-484 Front Matter....Pages 391-391 Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy....Pages 485-498 Back Matter....Pages 499-503 This book brings together the world's leading authorities on tumor immunology. It describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens This book brings together the worlds leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated. 0KaufmanFm.pdf -1 0kaufman01.pdf -1 0Kaufman02.pdf -1 0Kaufman03.pdf -1 0Kaufman04.pdf -1 0Kaufman05.pdf -1 0Kaufman06.pdf -1 0Kaufman07.pdf -1 0Kaufman08.pdf -1 0Kaufman09.pdf -1 0Kaufman10.pdf -1 0Kaufman11.pdf -1 0Kaufman13.pdf -1 0Kaufman14.pdf -1 0Kaufman15.pdf -1 0Kaufman16.pdf -1 0Kaufman17.pdf -1 0Kaufman18.pdf -1 0Kaufman19.pdf -1 0Kaufman20.pdf -1 0Kaufman21.pdf -1 0Kaufmanindex.pdf -1