Ganong's Review of Medical Physiology, Twenty Sixth Edition

It is difficult to believe that this preface signifies the fourth edition of Ganong's Review of Medical Physiology that our author group has overseen, and the 26th edition overall of this important reference work aimed at medical and other health professional students. As always, we have tried to maintain the highest standards of excellence that were promulgated by the original author, Fran Ganong, over the 46 years where he served, remarkably, as the sole author of the textbook. In this new edition, we have cast a fresh eye on the pedagogical approach taken in each chapter and section, and have focused particularly on including only material that is of the highest yield. We have thoroughly revised the learning objectives for every chapter, reorganized and updated the text to ensure that all objectives are clearly addressed in a logical order, aligned chapter summaries so that the take-home messages quickly address each learning objective in turn, and expanded the number of review questions so that readers also have the ability to check their understanding and retention of every objective covered. As a discipline evolves and new information emerges, there is a tendency simply to concatenate these concepts such that chapter structure degrades inevitably over time. With in-depth discussions amongst the author team and significant "spring-cleaning," we believe we have freshened and simplified the volume while also making sure that important new developments are incorporated. We are immensely thankful to Erica Wehrwein, PhD, Assistant Professor of Physiology and an award-winning instructor at Michigan State University, who took on the task of reviewing the book as a whole and providing specific and detailed feedback to us on each chapter. This new edition also welcomes a new member to the author team. We are delighted to have been able to recruit Jason X.-J. Yuan, MD, PhD, Professor of Medicine and Physiology as well as Chief of the Division of Translational and Regenerative Medicine and Associate Vice President for Translational Health Sciences at the University of Arizona, who has assumed responsibility for some cell physiology and cardiovascular topics, as well as the respiratory physiology section. We are particularly excited to have a physician-scientist on the team, who can guide us overall to focus on material that is of most benefit to those preparing for a career incorporating patient care. We are most grateful for the past contributions of Scott Boitano, PhD, whose other obligations meant that he could no longer serve as an author. We continue to be gratified by the many colleagues and students who contact us from all over the world to request clarification of material covered in the text, or to point out errors or omissions. We are especially grateful to Rajan Pandit, Lecturer in Physiology at Nepal Medical College, who has painstakingly offered dozens of suggestions for revision over the years. His efforts, and those of the many others whom we have not named, allow us to engage in a process of continual improvement. While, as always, any errors that remain in the book (inevitable in a complex project such as this) are the sole responsibility of the authorship team, we greatly value critical input, and urge readers once again to contact us with any suggestions or critiques. We thank you in advance both for such feedback, and also for your support of this new edition. by www.antitusif.com Cover......Page 1 Title Page......Page 2 Copyright Page......Page 4 Dedication......Page 7 About the Authors......Page 9 Contents......Page 13 Contents......Page 17 Preface......Page 19 Section I Cellular Molecular Basis for Medical Physiology......Page 21 1 General Principles Energy Production in Medical Physiology......Page 91 2 Overview of Cellular Physiology......Page 174 3 Immunity, Infection, Inflammation......Page 214 4 Excitable Tissue: Nerve......Page 245 5 Excitable Tissue: Muscle......Page 296 6 Synaptic Junctional Transmission......Page 333 7 Neurotransmitters Neuromodulators......Page 377 Section II Central Peripheral Neurophysiology......Page 379 8 Somatosensory Neurotransmission: Touch, Pain, Temperature......Page 418 9 Smell Taste......Page 439 10 Vision......Page 486 11 Hearing Equilibrium......Page 524 12 Reflex Voluntary Control of Posture Movement......Page 588 13 Autonomic Nervous System......Page 618 14 Electrical Activity of the Brain, SleepWake States, Circadian Rhythms......Page 648 15 Learning, Memory, Language, Speech......Page 677 Section III Endocrine Reproductive Physiology......Page 679 16 Basic Concepts of Endocrine Regulation......Page 697 17 Hypothalamic Regulation of Hormonal Functions......Page 731 18 The Pituitary Gland......Page 766 19 The Adrenal Medulla Adrenal Cortex......Page 826 20 The Thyroid Gland......Page 859 21 Hormonal Control of Calcium Phosphate Metabolism the Physiology of Bone......Page 894 22 Reproductive Development Function of the Female Reproductive System......Page 961 23 Function of the Male Reproductive System......Page 986 24 Endocrine Functions of the Pancreas Regulation of Carbohydrate Metabolism......Page 1038 Section IV Gastrointestinal Physiology......Page 1040 25 Overview of Gastrointestinal Function Regulation......Page 1091 26 Digestion Absorption of Nutrients......Page 1126 27 Gastrointestinal Motility......Page 1152 28 Transport Metabolic Functions of the Liver......Page 1176 Section V Cardiovascular Physiology......Page 1178 29 Origin of the Heartbeat the Electrical Activity of the Heart......Page 1218 30 The Heart as a Pump......Page 1252 31 Blood as a Circulatory Fluid the Dynamics of Blood Lymph Flow......Page 1330 32 Cardiovascular Regulatory Mechanisms......Page 1365 33 Circulation Through Special Regions......Page 1410 Section VI Respiratory Physiology......Page 1413 34 Introduction to Pulmonary Structure Mechanics......Page 1460 35 Gas Transport pH......Page 1497 36 Regulation of Respiration......Page 1534 Section VII Renal Physiology......Page 1536 37 Renal Function Micturition......Page 1597 38 Regulation of Extracellular Fluid Composition Volume......Page 1629 39 Acidification of the Urine Bicarbonate Excretion......Page 1651 Answers to Multiple Choice Questions......Page 1656 Index......Page 1724 Thoroughly updated to reflect the latest research and developments in important areas, this text incorporates examples from clinical medicine to illustrate important physiologic concepts. Applauded for its interesting and engagingly written style, it concisely covers every important topic without sacrificing depth or readability. The leading text on human physiology for more than four decades-enhanced by all new video tutorialsFor more than four decades, Ganong's Review of Medical Physiology has been helping those in the medical field understand human and mammalian physiology. Applauded for its interesting and engagingly written style, Ganong's concisely covers every important topic without sacrificing depth or readability, and delivers more detailed, high-yield information per page than any other similar text or review. Thoroughly updated to reflect the latest research and developments in important areas such as chronic pain, reproductive physiology, and acid-base homeostasis, Ganong's Review of Medical Physiology, Twenty-Sixth Edition incorporates examples from clinical medicine to illustrate important physiologic concepts. Ganong's will prove valuable to students who need a concise review for the USMLE, or physicians who want to keep pace with the ever-changing world of medical physiology.More than 600 full-color illustrationsTwo types of review questions: end-of-chapter and board-styleNEW! Increased number of clinical cases and flow chartsNEW! Video tutorials from the author; high-yield Frequently Asked Question feature with detailed explanations; improved legends that eliminate the need to refer back to the text The leading text on human physiology for more than four decades—enhanced by all new video tutorials A Doody's Core Title for 2020! For more than four decades, Ganong's Review of Medical Physiology has been helping those in the medical field understand human and mammalian physiology. Applauded for its interesting and engagingly written style, Ganong's concisely covers every important topic without sacrificing depth or readability, and delivers more detailed, high-yield information per page than any other similar text or review. Thoroughly updated to reflect the latest research and developments in important areas such as chronic pain, reproductive physiology, and acid-base homeostasis, Ganong's Review of Medical Physiology, Twenty-Sixth Edition incorporates examples from clinical medicine to illustrate important physiologic concepts. Ganong's will prove valuable to students who need a concise review for the USMLE, or physicians who want to keep pace with the ever-changing world of medical physiology. More than 600 full-color illustrations Two types of review questions: end-of-chapter and board-style NEW! Increased number of clinical cases and flow charts NEW! Video tutorials from the author; high-yield Frequently Asked Question feature with detailed explanations; improved legends that eliminate the need to refer back to the text The leading text on human physiology for more than four decades—enhanced by all new video tutorials A Doody’s Core Title for 2022! For more than four decades, Ganong’s Review of Medical Physiology has been helping those in the medical field understand human and mammalian physiology. Applauded for its interesting and engagingly written style, Ganong’s concisely covers every important topic without sacrificing depth or readability, and delivers more detailed, high-yield information per page than any other similar text or review. Thoroughly updated to reflect the latest research and developments in important areas such as chronic pain, reproductive physiology, and acid-base homeostasis, Ganong’s Review of Medical Physiology, Twenty-Sixth Edition incorporates examples from clinical medicine to illustrate important physiologic concepts. Ganong's will prove valuable to students who need a concise review for the USMLE, or physicians who want to keep pace with the ever-changing world of medical physiology. More than 600 full-color illustrations Two types of review questions: end-of-chapter and board-style NEW! Increased number of clinical cases and flow charts NEW! Video tutorials from the author; high-yield Frequently Asked Question feature with detailed explanations; improved legends that eliminate the need to refer back to the text