Ganoderma and Health: Pharmacology and Clinical Application (Advances in Experimental Medicine and Biology Book 1182)

This book presents a state-of-the-art report on recent advances concerning Ganoderma and where the field is going. Although some older work is also cited, the main focus is on advances made over the past 20 years in the pharmacology and clinical applications of Ganoderma. Ganoderma lucidum (Lingzhi) has been used as a traditional medicine in Asian countries to maintain health and to treat diseases for more than two thousand years. Recently, its value has been demonstrated in preventing and treating certain diseases, such as tumors, liver disorders, renal injury, hypercholesterolemia, obesity, cerebral ischemia reperfusion, bronchitis etc. In addition, laboratory and clinical studies have confirmed that the chemical components of Ganoderma, such as Ganoderma lucidum polysaccharide peptides and triterpenes isolated from the fruiting body of Ganoderma lucidum, produce diverse pharmacological effects. Ganoderma and its components play an important part in antioxidant stress, radical-scavenging, immunomodulation, and intracellular signaling regulation, and accordingly warrant further study. This book systematically reviews the latest advances in our understanding of pharmacology and clinical applications of Ganoderma, and offers researchers and graduate students valuable new insights into the pharmacology and clinical applications of Ganoderma and related products. Front Matter ....Pages i-viii Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism (Xin Wang, Zhibin Lin)....Pages 1-37 Antitumor Effect of Ganoderma (Lingzhi) Mediated by Immunological Mechanism and Its Clinical Application (Zhibin Lin, Lixin Sun)....Pages 39-77 Cellular and Molecular Mechanism of Ganoderma (Lingzhi) Against Tumor (Yu Sun, Lixin Sun)....Pages 79-118 Protective Effect of Ganoderma (Lingzhi) on Radiation and Chemotherapy (Lihua Chen, Abudumijiti Abulizi, Min Li)....Pages 119-142 Neuropharmacological Effect and Clinical Applications of Ganoderma (Lingzhi) (Xiangyu Cui, Yonghe Zhang)....Pages 143-157 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Brain Injury (Yazhu Quan, Ang Ma, Baoxue Yang)....Pages 159-180 Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System (Jia Meng, Baoxue Yang)....Pages 181-199 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Diabetes (Qian Liu, Lu Tie)....Pages 201-215 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury (Zhiwei Qiu, Dandan Zhong, Baoxue Yang)....Pages 217-242 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Renal Diseases and Clinical Applications (Xiaoqiang Geng, Dandan Zhong, Limin Su, Baoxue Yang)....Pages 243-262 Anti-osteoporosis Effect of Ganoderma (Lingzhi) by Inhibition of Osteoclastogenesis (Yajun Yang, Baoxue Yang)....Pages 263-269 Antioxidative and Free Radical Scavenging Activity of Ganoderma (Lingzhi) (Zhibin Lin, Aoyi Deng)....Pages 271-297 Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness (Yan Pan, Zhibin Lin)....Pages 299-309 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Skin Diseases and Care (Zhuming Yin, Baoxue Yang, Huiwen Ren)....Pages 311-321