Gamete and Embryo-fetal Origins of Adult Diseases [recurso electrónico] $c

The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians. Editor He-Feng Huang, M.D., is Professor and President of Women’s Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph.D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China. The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians. Editor He-Feng Huang, M.D., is Professor and President of Women's Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph. D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China Front Matter....Pages i-ix Physiology of Gametogenesis....Pages 1-38 Physiology of Embryonic Development....Pages 39-59 Adverse Intrauterine Environment and Gamete/Embryo-Fetal Origins of Diseases....Pages 61-78 Gamete/Embryo-Fetal Origins of Diabetes....Pages 79-93 Gamete/Embryo-Fetal Origins of Cardiovascular Diseases....Pages 95-108 Gamete/Embryo-Fetal Origins of Tumours....Pages 109-136 Gamete/Embryo-Fetal Origins of Obesity....Pages 137-156 Gamete/Embryo-Fetal Origins of Mental Disorders....Pages 157-171 Gamete/Embryo-Fetal Origins of Infertility....Pages 173-196 Assisted Reproductive Technology and Gamete/Embryo-Fetal Origins of Diseases....Pages 197-219 Erratum....Pages E1-E1 Back Matter....Pages 221-222