Fundamentals of Biochemical Pharmacology : Pergamon International Library of Science, Technology, Engineering and Social Studies

Fundamentals of Biochemical Pharmacology explains the molecular aspects of drugs and the changes in bio-chemical systems. The cellular movements that result from such changes are also evaluated. Biochemical lesion is extensively defined in the book. A discussion on electromagnetic radiation is also provided. A chapter of the book is devoted to the principles of electronic and nuclear magnetic resonance. The principles and applications of mass spectrometry and combined gas chromatography are then discussed. The scientific advances made with the use of immunological methods are the focus of a section of the book. Another section provides an introduction to the kinetic properties of reactions made by enzymes. The process called homogenization is clearly explained along with a discussion on the use of electron microscopy. Autoradiography shows the distribution of compounds at the subcellular level. The theoretical background of molecular spectroscopy is presented completely. The book is intended for chemists, biochemists, physicists, micro-biologists, zoologists, and botanists . Content: OTHER TITLES OF INTEREST, Page ii Front Matter, Page iii Copyright, Page iv Preface, Pages ix-xi, Z.M. BACQ List of Authors, Pages xiii-xiv 1 - Introduction to Optical Methods, Pages 3-12, J. RENSON, P. KREMERS 2 - Electronic and Nuclear Magnetic Resonances, Pages 13-19, J. DEPIREUX 3 - Mass Spectrometry, Pages 21-28, C.G. HAMMAR 4 - Isotopic Methods and Activation Analysis, Pages 29-34, L. MANARA 5 - Isolation and Purification Procedures, Pages 35-49, I.M. HAIS 6 - Immunochemistry and Radioimmunochemistry, Pages 51-58, P. FRANCHIMONT 7 - Introduction to Enzyme Kinetics, Pages 59-86, CL. LIéBECQ 8 - Centrifugation of Subcellular Components, Pages 87-96, R. WATTIAUX 9 - Electron Microscopy, Pages 97-100,100a,101, F. CLEMENTI 10 - Histoautoradiography, Pages 103-107,107a,107b,107c, P.G. WASER 11 - Biochemical and Pharmacological Aspects of Histochemistry, Pages 109-110,110a,111-113, B. EHINGER 12 - Animals and Isolated Organs, Pages 115-119, Z.M. BACQ 13 - Electrophysiological Methods, Pages 121-130, R.Y. ILYUTCHENOK, M.A. GILINSKY 14 - Behavioural Techniques, Pages 131-136, M. RICHELLE, M.J. DALLEMAGNE 1 - The Concept of the Biochemical Lesion, Pages 139-142, Z.M. BACQ 2 - Functions of Subcellular Structures 2.1. BACTERIAL WALLS AND MEMBRANES, Pages 143-156,156a,156b,156c,156d,157-184 3 - Transfer of Ions and Molecules Across Cellular Membranes, Pages 185-202, E. SCHOFFENIELS 4 - Pharmacokinetics, Pages 203-219, I. JANKŮ 5 - Synaptic Vesicles, Specific Granules, Autopharmacology 5.1. CHOLINERGIC TRANSMISSIONS, Pages 221-224,224a,225-260,260a,261-344,344a,345-365 6 - Drug-receptor Interactions, Pages 367-410, M. WENKE 7 - Chelating Agents, Pages 411-415, A. CATSCH 8 - Effects of Drugs on Structure, Biosynthesis and Catabolism of Nucleic Acids, Proteins, Carbohydrates and Lipids, Pages 417-570 9 - Biotransformation of Drugs, Pages 571-572,572a,572b,573-609, T.E. GRAM, J.R. GILLETTE 10 - Pharmacogenetics, Pages 611-620, H.W. GOEDDE, K. ALTLAND 11 - Comparative Pharmacology, Pages 621-625, E. FLOREY INDEX, Pages 627-659