Functionalized Nanomaterials for the Management of Microbial Infection. A Strategy to Address Microbial Drug Resistance. A volume in Micro and Nano Technologies
معرفی کتاب «Functionalized Nanomaterials for the Management of Microbial Infection. A Strategy to Address Microbial Drug Resistance. A volume in Micro and Nano Technologies» نوشتهٔ Rabah Boukherroub, Sabine Szunerits and Djamel Drider (Eds.)، منتشرشده توسط نشر Elsevier Science & Technology Books در سال 2016. این کتاب در فرمت pdf، زبان انگلیسی ارائه شده است.
__Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance__ introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. 3.3.2.2 Nanocarriers can be Designed to Increase Local Antibiotic Delivery -- 3.3.2.3 Nanocarriers Can Shuttle Antibiotics Inside Bacterial Cells -- 3.3.2.4 Responsive Nanoparticles: Antibiotic Release on Demand -- 3.4 Conclusion -- References -- 4 Metal Nanoparticles for Microbial Infection -- 4.1 Introduction -- 4.2 Silver Nanoparticles for Microbial Infection -- 4.2.1 Silver Nanoparticles Against Bacterial Infection -- 4.2.2 Silver Nanoparticles Against Fungal Infection -- 4.2.3 Silver Nanoparticles Against Viral Infection -- 4.2.4 Silver Nanoparticles Against Protozoal Infection -- 4.2.5 Medical Applications of Silver Nanoparticles -- 4.3 Copper Nanoparticles for Microbial Infection -- 4.3.1 Copper Nanoparticles Against Bacterial Infection -- 4.3.2 Copper Nanoparticles Against Fungal Infection -- 4.3.3 Medical Applications of Copper Nanoparticles -- 4.4 Gold Nanoparticles for Microbial Infection -- 4.4.1 Gold Nanoparticles for Therapeutic Intervention -- 4.4.2 Gold Nanoparticles for Antimicrobial Drug Delivery -- 4.4.3 Gold Nanoparticles for Photodynamic Therapy -- 4.4.4 Gold Nanoparticles for Photothermal Treatment -- 4.4.5 Gold Nanoparticles for Diagnostic Applications -- 4.5 Safety Considerations -- 4.6 Conclusion -- References -- 5 Lipid-Based Nanopharmaceuticals in Antimicrobial Therapy -- 5.1 Nanopharmaceuticals -- 5.2 Lipid-Based Nanopharmaceuticals -- 5.2.1 Liposomes -- 5.2.2 Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) -- 5.2.3 Nanostructured Lipid Carriers (NLCs) -- 5.3 Antimicrobial Therapy of Interest -- 5.4 Potential of Nanopharmaceuticals in Treatment of Microbial Infections -- 5.4.1 Fusogenic Liposomes -- 5.4.2 Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) -- 5.5 Potential of Lipid-Based Nanopharmaceuticals for Antimicrobial Therapy Related to Route of Administration 5.5.1 Systemic Infections (Parenteral Route) -- 5.5.2 Systemic Infections (Oral Route) -- 5.5.3 Skin Infections -- 5.5.4 Vaginal Infections -- 5.5.4.1 Bacterial and Fungal Infections -- Liposomes -- Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs) -- 5.5.4.2 Treatment of Viral Infections -- Liposomes -- 5.5.4.3 Prophylaxis of Viral Infections -- Liposomes -- Solid Lipid Nanoparticles (SLNs) -- 5.5.5 Lung/Pulmonary Infections -- 5.5.6 Local Therapy of Eye Infections -- 5.5.7 Periodontal Infections -- 5.6 Toxicity -- 5.7 Current Limitations -- 5.8 Perspectives -- 5.9 Conclusions -- References -- 6 Organic Polymeric Nanomaterials as Advanced Tools in the Fight Against Antibiotic-Resistant Infections -- 6.1 Introduction: Antibiotic Resistance-A Global Threat to Public Health -- 6.2 Nanoantibiotics-A New Paradigm to Fight Against Antibiotic Resistance Bacteria -- 6.3 Polymeric Architectures Relevant to Drug Delivery Applications -- 6.4 Types, Structures, and Supramolecular Morphologies of Polymeric Nanocarriers -- 6.5 Methods for Preparation of Drug-Loaded Polymeric Nanoparticles -- 6.5.1 Preparation of Polymeric Nanoparticles Starting With Monomers -- 6.5.1.1 Conventional Emulsion Polymerization -- 6.5.1.2 Mini-Emulsion Polymerization -- 6.5.1.3 Micro-Emulsion Polymerization -- 6.5.1.4 Interfacial Polymerization -- 6.5.2 Synthesis of Polymeric Nanoparticles From Preformed Polymers -- 6.5.2.1 Nanoprecipitation Method -- 6.5.2.2 Emulsion-Solvent Diffusion Method -- 6.5.2.3 Emulsion-Solvent Evaporation Method -- 6.5.2.4 Salting-Out Method -- 6.5.2.5 Dialysis Method -- 6.5.2.6 Methods Based on the Application of an Electric Field -- Fabrication of Polymer Nanofibers Through Electrospinning -- Fabrication of Polymer Nanoparticles Through Electrospraying -- 6.6 Polymer-Based Nanomaterials for Antiinfectious Therapy 6.6.1 Antimicrobial Polymers -- 6.6.1.1 Linear Polymers Based on Diallylammonium Monomers -- 6.6.1.2 Linear Polymers Based on Acrylic and Methacrylic Monomers -- 6.6.1.3 Linear Polycarbonates -- 6.6.1.4 Linear Polymers Containing Aromatic Heterocyclic Structures -- 6.6.1.5 Amphiphilic Polynorbornene and Polyoxanorbornene Derivatives -- 6.6.1.6 Ionenes -- 6.6.1.7 Block Copolymers -- 6.6.1.8 Antimicrobial Dendrimers -- 6.6.1.9 Polymers Mimicking Natural Cationic Host Defense Peptides -- 6.6.1.10 Polysaccharides -- 6.6.2 Polymer-Antibiotic Conjugates -- 6.6.2.1 Synthesis of Antibiotic-Polymer Conjugates From Preformed Polymers -- 6.6.2.2 Synthesis of Antibiotic-Polymer Conjugates From Monomer Prodrugs -- 6.6.3 Smart Supramolecular Nanovehicles for Antibiotic Delivery Based on Organic Polymers and Enhancement of Antimicrobial ... -- 6.6.3.1 pH-Responsive Antibiotic Delivery -- 6.6.3.2 Enzyme-Sensitive Antibiotic Delivery -- 6.6.3.3 Improving the Antimicrobial Activity of Currently Used Antibiotics Through Nanoencapsulation -- 6.6.4 Dendrimers -- 6.7 Concluding Remarks and Future Perspectives -- References -- 7 Bacteriocins and Nanotechnology -- 7.1 Introduction -- 7.2 Stability of Bacteriocins -- 7.3 Immune response to bacteriocins -- 7.4 Preclinical Trials Conducted on Bacteriocins -- 7.5 Delivery Systems -- 7.6 Conclusions -- References -- 8 Graphene-Microbial Interactions -- 8.1 Introduction -- 8.2 Graphene, Graphene Oxide (GO) and Reduced Graphene Oxide (rGO): Production and Characterization -- 8.3 Inhibition of Bacterial Attachment and Antibacterial Activity of Graphene-Coated Surfaces -- 8.4 Interaction of GO and rGO With Bacteria in Suspension -- 8.5 Antibacterial Activity of Nanoparticle Decorated GO and rGO -- 8.6 Conclusion and Perspectives -- Acknowledgments -- References -- Index -- Back Cover Front Cover -- Functionalized Nanomaterials for the Management of Microbial Infection -- Copyright Page -- Contents -- List of Contributors -- Preface -- 1 Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon -- 1.1 Resistance to Antibiotics -- 1.2 Resistance to Bacteriocins Produced by Gram-Positive Bacteria (GPB) -- 1.3 Conclusion and Prospects -- Acknowledgments -- References -- 2 The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR) -- 2.1 Introduction -- 2.2 AMR in Foodborne Pathogenic Bacteria -- 2.3 AMR in Food-Related Beneficial Microbes -- 2.4 Routes of Transmission of AMR Throughout the Food Chain -- 2.4.1 Foods of Animal Origin -- 2.4.2 Foods of Nonanimal Origin -- 2.4.3 Primary Production and Food Processing Environments and Food Processing Technologies -- 2.4.3.1 Role of Biocides in AMR Acquisition and Spread -- 2.4.3.2 Food Processing Technologies and AMR -- 2.5 Conclusions -- References -- 3 Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment -- 3.1 Introduction -- 3.1.1 Antimicrobial Treatment: In Desperate Need of a Wind of Change -- 3.1.2 The Biofilm Lifestyle -- 3.2 How Biofilms Pose a Challenge to the Diffusion of Antibiotics -- 3.2.1 Mass Transport Phenomena in Biofilms -- 3.2.2 Dense Cell Clusters -- 3.2.3 Binding Interactions Between Antibiotics and Matrix Constituents -- 3.2.3.1 Physicochemical Binding to Matrix Polymers -- 3.2.3.2 Inactivation of Antibiotics by Enzymes Present in the Biofilm Matrix -- 3.3 How to Improve Antibiotic Delivery to Biofilm Cells? -- 3.3.1 Interference With the Biofilm Structure -- 3.3.2 Nanocarriers for Improved Delivery of Antibiotics in Biofilms -- 3.3.2.1 Nanocarriers Protect Antibiotics From Interactions With Biofilm Components
دانلود کتاب Functionalized Nanomaterials for the Management of Microbial Infection. A Strategy to Address Microbial Drug Resistance. A volume in Micro and Nano Technologies
Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens.
The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle.
- Provides the information users need to integrate antibacterial nanoparticles into future treatments
- Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges
- Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection